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This book is for readers who do not specialize in biochemistry but who require a strong grasp of biochemical principles. The goal of this book is to enrich the coverage of chemistry while better highlighting the biological context. Once concepts and problem-solving skills have been mastered, readers are prepared to tackle the complexities of science, modern life, and their chosen professions.
Biochemistry: The Molecular Basis of Life is the ideal text for students who do not specialize in biochemistry but who require a strong grasp of biochemical principles. The goal of this edition has been to enrich the coverage of chemistry while better highlighting the biological context. Once concepts and problem-solving skills have been mastered, students are prepared to tackle the complexities of science, modern life, and their chosen professions. NEW! Online Homework System from Sapling Learning. Oxford University Press has partnered with Sapling Learning to produce an online homework and instructional solution for the McKee and McKee Biochemistry: The Molecular Basis of Life textbook. The text that presents the coverage you need with the relevance your students want is now available with the most powerful online homework system in the industry. The relationship between Oxford University Press and Sapling Learning is based on: * Creating the highest-quality content * Providing unparalleled customer service to you and your students * Offering the McKee/Sapling Learning package at the most affordable price Visit a href="http://www.saplinglearning.com/partners/partner_page_oxford.php"http://www.saplinglearning.com/partners/partner_page_oxford.php/a to learn more about Sapling Learning and how pairing this incredible system with McKee and McKee's Biochemistry: The Molecular Basis of Life will help improve your instruction and your students' learning.
Biochemistry: The Molecular Basis of Life is the ideal text for students who do not specialize in biochemistry but who require a strong grasp of biochemical principles. The goal of this edition has been to enrich the coverage of chemistry while better highlighting the biological context. Once concepts and problem-solving skills have been mastered, students are prepared to tackle the complexities of science, modern life, and their chosen professions. NEW! Online Homework System from Sapling Learning. Oxford University Press has partnered with Sapling Learning to produce an online homework and instructional solution for the McKee & McKee Biochemistry: The Molecular Basis of Life textbook. The text that presents the coverage you need with the relevance your students want is now available with the most powerful online homework system in the industry. The relationship between Oxford University Press and Sapling Learning is based on: *Creating the highest-quality content *Providing unparalleled customer service to you and your students *Offering the McKee/Sapling Learning package at the most affordable price Visit http://www.saplinglearning.com/partners/partner_page_oxford.php to learn more about Sapling Learning and how pairing this incredible system with McKee & McKee's Biochemistry: The Molecular Basis of Life will help improve your instruction and your students' learning. Distinctive Features *A Review of Basic Principles. To ensure that all students are sufficiently prepared for acquiring a meaningful understanding of biochemistry, the first four chapters - now streamlined for easier coverage and self-study assignment - review the principles of relevant topics such as organic functional groups, noncovalent bonding, thermodynamics, and cell structure. *Chemical and Biological Principles in Balance. Comprehensive coverage offers the flexibility for each instructor to decide how much chemistry or biology to present. Chemical mechanisms are always presented within the physiological context of the organism. *Real-World Relevance. Because students who take the survey of biochemistry course come from a range of backgrounds and have diverse career goals, the fifth edition consistently demonstrates the fascinating connections between biochemical principles and the fields of medicine, nutrition, agriculture, bioengineering, and forensics. *The most robust Problem-Solving Program available. In-chapter "Worked Problems" illustrate how quantitative problems are solved, and dozens of "Questions" interspersed throughout the chapters provide students with opportunities to put their knowledge into action right when new concepts and high-interest topics are introduced. Chapter overviews, end-of-chapter "Review Questions" and "Thought Questions," and key-word lists help students grasp the big picture in each chapter. *Simple, Clear Illustrations. Biochemical concepts often require a high degree of visualization, and the McKee & McKee art program brings complex processes to life. Over 700 full-color figures, many newly enhanced for a more vivid presentation in three dimensions and consistent scale and color for chemical structures. *Currency. The fifth edition has been extensively updated with recent developments in the field, while remaining focused on the "big-picture" principles that are the focus of the one-term biochemistry course. New to this Edition *Chapter-opening Vignettes, an all-new feature of the fifth edition, give biological motivation. These 19 essays include the nature and diversity of life, the ocean's dark secret life, spider silk, humans and enzymes, sweet and bitter taste in diet, metabolism and jet engines, evolution as chance and necessity, oxygen's molecular paradox, global warming and renewable energy, the Gulf dead zone, Parkinson's disease and Alzheimer's, hypertension and uric acid, what makes us human, the medical mystery of DNA and chimeras, and the superbug MRSA *New "Biochemistry in Perspective" boxes (9 new in all) on cell regulation and metabolism, protein folding and human disease, quantum tunneling and catalysis, wine production, turbo design dangers, myocardial infarct, the hormone cascade system, and trapped ribosomes *New "Biochemistry in the Lab" boxes on protein sequence analysis and glycomics *Beefed-up chemical coverage with increased emphasis on mechanisms *Enhanced coverage of cutting-edge topics including RNAi, epigenetics and the epigenome, macromolecular crowding, GLUT transporters, systems biology, and the contribution of dietary fructose to the current epidemics of obesity and type II diabetes *"Key Concept" icons, plus additional icons for biomedical applications with new labels identifying the application. Other icons point to JMOL visualization software. *20% more end-of-chapter review and thought questions that were already doubled in number and expanded in range of difficulty in the fourth edition *Updated coverage of coenzymes, viruses, and biotechnology *Extended coverage of amino acids, proteins, enzymes, carbohydrates, nucleic acids, and genetic information--the basic building blocks--and trimmed down coverage of metabolism (especially nitrogen metabolism) *The entire text is now tied to NEW Sapling Learning online homework system! Oxford University Press has partnered with Sapling Learning to produce an online homework and instructional solution for Biochemistry: The Molecular Basis of Life textbook. The text that presents the coverage you need with the relevance your students want is now available with the most powerful online homework system in the industry.
Vital Forces tells the history of the 'biochemical revolution', a period of unprecedentedly rapid advance in human knowledge that profoundly affected our view of life and laid the foundation for modern medicine and biotechnology. The story is told in a clear, engaging, and absorbing manner. This delightful work relates the fascinating and staggering advances in concepts and theories over the last 200 years and introduces the major figures of the times. Vital Forces also describes the discovery of the molecular basis of life through the stories of the scientists involved, including such towering figures as Louis Pasteur, Gregor Mendel, Linus Pauling, and Francis Crick. Combining science and biography into a seamless chronological narrative, the author brings to life the successes and failures, collaborations and feuds, and errors and insights that produced the revolution in biology. * Vividly describes dramatic scientific discoveries, personalities, feuds and rivalries * Answers a general readers quest to understand the nature of life, and the relevance of biochemistry/molecular biology to modern medicine, industry and agriculture.
Successfully fighting cancer starts with understanding how it begins. This thoroughly revised 3rd Edition explores the scientific basis for our current understanding of malignant transformation and the pathogenesis and treatment of cancer. A team of leading experts thoroughly explain the molecular biologic principles that underlie the diagnostic tests and therapeutic interventions now being used in clinical trials and practice. Incorporating cutting-edge advances and the newest research, the book provides thorough descriptions of everything from molecular abnormalities in common cancers to new approaches for cancer therapy. Features sweeping updates throughout, including molecular targets for the development of anti-cancer drugs, gene therapy, and vaccines...keeping you on the cutting edge of your specialty. Offers a new, more user-friendly full-color format so the information that you need is easier to find. Presents abundant figures-all redrawn in full color-illustrating major concepts for easier comprehension. Features numerous descriptions of the latest clinical strategies-helping you to understand and take advantage of today’s state-of-the-art biotechnology advances.
The book describes how the balance between pro- and anti-inflammatory molecules is related to health and disease. It is suggested that many diseases are initiated and their progress is influenced by inflammatory molecules and a decrease in the production and/or action of anti-inflammatory molecules and this imbalance between pro- and anti-inflammatory molecules seems to have been initiated in the perinatal period. This implies that strategies to prevent and manage various adult diseases should start in the perinatal period. An alteration in the metaolism of essential fatty acids and their anti-inflammatory molecules such as lipoxins, resolvins, protecitns, maresins and nitrolipids seems to play a major role in the pathobiology of several adult diseases. Based on these concepts, novel therapeutic approaches in the management of insulin resistance, obesity, type 2 diabetes mellitus, metabolic syndrome, cancer, lupus, rheumatoid arthritis and other auto-immune diseases are presented. Based on all these evidences, a unified concept that several adult diseases are due to an alteration in the balance between pro- and anti-inflammatory molecules is discussed and novel methods of their management are presented.
Biochemical and Molecular Basis of Pediatric Disease, Fifth Edition has been a well-respected reference in the field for decades. This revision continues the strong focus on understanding the pathogenesis of pediatric disease, emphasizing not only the important role of the clinical laboratory in defining parameters that change with the disease process, but also the molecular basis of many pediatric diseases. - Provides a fully-updated resource with more color illustrations - Focuses on the biochemical and molecular basis of disease as well as the analytical techniques - Defines important differences in the pathophysiology of diseases, comparing childhood with adult
Molecular Nature is a richly illustrated guide to the extraordinary diversity of molecules that are responsible for life. David Goodsell, author of the highly-praised book, The Machinery of Life, has synthesized a vast amount of data in a manner that is accessible to the general reader. Molecular Nature examines topics ranging from the shape of cells to the molecules responsible for digestion, immunity, and thought. The author's unique combination of scientific and artistic talents make this a readable, stimulating and highly evocative book. About the Author: David Goodsell is in the Department of Molecular Biology at the Research Institute of Scripps Clinic in La Jolla, California. His research involves computer graphics and X-ray crystallography. He is the author of The Machinery of Life (Springer-Verlag, 1992), and his artwork has been shown at exhibitions on science and art.
**Selected for Doody's Core Titles® 2024 in Biochemistry** Human Biochemistry, Second Edition provides a comprehensive, pragmatic introduction to biochemistry as it relates to human development and disease. Here, Gerald Litwack, award-wining researcher and longtime teacher, discusses the biochemical aspects of organ systems and tissue, cells, proteins, enzymes, insulins and sugars, lipids, nucleic acids, amino acids, polypeptides, steroids, and vitamins and nutrition, among other topics. Fully updated to address recent advances, the new edition features fresh discussions on hypothalamic releasing hormones, DNA editing with CRISPR, new functions of cellular prions, plant-based diet and nutrition, and much more. Grounded in problem-driven learning, this new edition features clinical case studies, applications, chapter summaries, and review-based questions that translate basic biochemistry into clinical practice, thus empowering active clinicians, students and researchers. - Presents an update on a past edition winner of the 2018 Most Promising New Textbook (College) Award (Texty) from the Textbook and Academic Authors Association and the PROSE Award of the Association of American Publishers - Provides a fully updated resource on current research in human and medical biochemistry - Includes clinical case studies, applications, chapter summaries and review-based questions - Adopts a practice-based approach, reflecting the needs of both researchers and clinically oriented readers