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A discussion of the chemical compounds produced by organisms living under extreme conditions that may have potential as drugs or leads to novel drugs for human use. This SpringerBrief deals with bioactive materials from terrestrial extremophiles.
The book compiles the latest studies on microorganisms thriving in extreme conditions. Microbes have been found in extremely high and low temperatures, highly acidic to saline conditions, from deserts to the Dead sea, from hot-springs to underwater hydrothermal vents- the diversity is incredible. The various chapters highlight the microbial life and describe the mechanisms of tolerance to these harsh conditions, and show how an understanding of these phenomena can help us exploit the microbes in biotechnology. The theme of the book is highly significant since life in these environments can give vital clues about the origin and evolution of life on earth, as a lot of these conditions simulate the environment present billions of years ago. Additionally, the study of adaptation and survival of organisms in such environments can be important for finding life on other planets. This book shall be useful for students, researchers and course instructors interested in evolution, microbial adaptations and ecology in varied environments.
Volatiles and Metabolites of Microbes compiles the latest research and advancement in the field of volatiles, metabolites synthesized from the microbial strains such as actinomycetes, bacteria, cyanobacteria, and fungal species and their potential applications in the field of healthcare issue and sustainable agriculture. There is an urgent need to explore new and advanced biological methods for health industries and sustainable agriculture and to protect the environment from environmental pollution or contaminates, global warming, and also control the health of human beings from the side effects of various pharmaceuticals products. Focusing all these factors, Volatiles and Metabolites of Microbes explores new aspects of microorganism in terms of volatiles, enzymes, bioactive compounds synthesized from the microbes and their potential applications in the field of sustainable agriculture and health-related issues - Provides a broad aspect about volatiles, bioactive compounds, and secondary metabolites of microbes compiled in one cover - Gives the latest research and advancement in the field of volatiles, secondary metabolites, and bioactive compounds synthesized from the different microbial strains - Responds to new developments in the detection of the complex compound structures of volatiles - Offers insight to a very broad audience in Biotechnology, Applied Microbiology, Agronomy, and Pathology
​This SpringerBrief sheds new light on bioactive materials from extremophiles with the focus on the biosynthesis processes and related genomics. It deals with all aspects of the chemical compounds produced by organisms living under extreme conditions that may have potential as drugs or lead to novel drugs for human use.
Over the last decades, scientists have been intrigued by the fascinating organisms that inhabit extreme environments. These organisms, known as extremophiles, thrive in habitats which for other terrestrial life-forms are intolerably hostile or even lethal. Based on such technological advances, the study of extremophiles has provided, over the last few years, ground-breaking discoveries that challenge the paradigms of modern biology. In the new bioeconomy, fungi in general, play a very important role in addressing major global challenges, being instrumental for improved resource efficiency, making renewable substitutes for products from fossil resources, upgrading waste streams to valuable food and feed ingredients, counteracting life-style diseases and antibiotic resistance through strengthening the gut biota, making crop plants more robust to survive climate change conditions, and functioning as host organisms for production of new biological drugs. This range of new uses of fungi all stand on the shoulders of the efforts of mycologists over generations. The book is organized in five parts: (I) Biodiversity, Ecology, Genetics and Physiology of Extremophilic Fungi, (II) Biosynthesis of Novel Biomolecules and Extremozymes (III) Bioenergy and Biofuel synthesis, and (IV) Wastewater and biosolids treatment, and (V) Bioremediation.
This book focuses on the fungi found in one of the most pristine regions on Earth: Antarctica. It discusses the fungal occurrence in all substrates of the region, including soil, seawater, lake and marine sediments, rocks, ice, and snow. It also addresses the impact of climate changes on these organisms, the genomic techniques developed to study them, and how a number of compounds, such as antibiotics and enzymes, produced by the Antarctic fungi can be used in medicine, agriculture and the chemical industry.
Scientific research on cold-adapted microorganisms (specifically polar microbes) is of great interest, since Arctic and Antarctic regions harbor diverse and active populations of microorganisms. However, these microorganisms are subject to impacts of environmental perturbations. For example, climate change will modulate the distribution and activity of many cyanobacteria and algal species in polar environments that contribute significantly to global carbon fixation and oxygen production. Moreover, many microorganisms that have remained frozen for thousands of years can revive their metabolic activity and re-join the modern microbial community. For survival in freezing environments, polar microorganisms have established specific regulatory mechanisms which are now being challenged by new, rapidly changing environmental conditions. Remarkable progress has been made to uncover microbial adaptation to anthropogenic activities such as high irradiance, nutritional deprivation, UV-B radiation, heat, cold, desiccation, and heavy metals. Studies have enabled a basic understanding of gene regulatory pathways for morphological, physiological, metabolic, and genetic adaptations to various environmental stresses. To further elucidate physiological adaptation mechanisms and molecular diversity in polar regions, this Research Topic is focused on microbes in polar regions, looking at their biodiversity, ecological adaptations, the impact of climate change on their lifestyles, and biotechnological application of microbes for a sustainable future.
Functional and Preservative Properties of Phytochemicals examines the potential of plant-based bioactive compounds as functional food ingredients and preservative agents against food-spoiling microbes and oxidative deterioration. The book provides a unified and systematic accounting of plant-based bioactive compounds by illustrating the connections among the different disciplines, such as food science, nutrition, pharmacology, toxicology, combinatorial chemistry, nanotechnology and biotechnological approaches. Chapters present the varied sources of raw materials, biochemical properties, metabolism, health benefits, preservative efficacy, toxicological aspect, safety and Intellectual Property Right issue of plant-based bioactive compounds. Written by authorities within the field, the individual chapters of the book are organized according to the following practical and easy to consult format: introduction, chapter topics and text, conclusions (take-home lessons), and references cited for further reading. - Provides collective information on recent advancements that increase the potential use of phytochemicals - Fosters an understanding of plant-based dietary bioactive ingredients and their physiological effects on human health at the molecular level - Thoroughly explores biotechnology, omics, and bioinformatics approaches to address the availability, cost, and mode of action of plant-based functional and preservative ingredients
​This SpringerBrief sheds new light on bioactive materials from marine extremophiles. It deals with all aspects of the chemical compounds produced by organisms living under extreme conditions that may have potential as drugs or lead to novel drugs for human use.
The book entitled “Biodiversity of Marine Microbes” aims at highlighting the significance of marine microbes as primary producers, their contribution in complex ecological processes and their roles in biogeochemical cycles and ecosystem functioning. The book includes five research papers covering the diversity and composition of marine microbial communities representing all three domains of life in various marine environments, including coastal eutrophic areas, ice waters, and lagoons. One paper examines the diversity and succession of bacterial and archaeal communities from coastal waters in mesocosm experiments. The combination of classical tools with novel technological advances implemented in the methods of the papers offered an opportunity to answer fundamental questions and shed light on the complex and diverse life of marine microbes.