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Megastructure proposals by the Japanese Metabolism group are commonly identified with the concept of utopia. Beyond this partial understanding, Agnes Nyilas suggests that rather than being merely utopian, the Megastructure of Metabolism represents a uniquely amalgam genre: the myth camouflaged as utopia. Although its Megastructure seemingly describes a desirable future condition as utopia does, it also comprises certain cultural images rooted in the collective (un)conscious of Japanese people, in accordance with the general interpretation of myth. The primary narrative of Beyond Utopia thus follows the gradual unfolding of the myth-like characteristics of its Megastructure. Myth is dealt here as an interdisciplinary subject in line with contemporary myth theories. After expounding the mechanism underlying the growing demand for a new myth in architecture (the origin of the myth), Part I discovers the formal characteristics of the Megastructure of Metabolism to give a hint of the real intention behind it. Based on this, Part II is a reexamination of their design methods, which aims to clarify the function of the myth and to suggest the meaning behind it. Finally, Part III deals with the subject matter of the myth by disclosing the meaning unfolding in the story, and suggests a new reading of Metabolism urban theory: as an attempt to reconsider the traditional Japanese space concept.
Metabolic Ecology Most of ecology is about metabolism, the ways that organisms use energy and materials. The energy requirements of individuals (their metabolic rates) vary predictably with their body size and temperature. Ecological interactions are exchanges of energy and materials between organisms and their environments. Therefore, metabolic rate affects ecological processes at all levels: individuals, populations, communities and ecosystems. Each chapter focuses on a different process, level of organization, or kind of organism. It lays a conceptual foundation and presents empirical examples. Together, the chapters provide an integrated framework that holds the promise for a unified theory of ecology. The book is intended to be accessible to upper-level undergraduates and graduate students, but also of interest to senior scientists. Its easy-to-read chapters and clear illustrations can be used in lecture and seminar courses. This is an authoritative treatment that will inspire future generations to study metabolic ecology.
The popular narrative of "globesity" posits that the adoption of Western diets is intensifying obesity and diabetes in the Global South and that disordered metabolisms are the embodied consequence of globalization and excess. In Metabolic Living Harris Solomon recasts these narratives by examining how people in Mumbai, India, experience the porosity between food, fat, the body, and the city. Solomon contends that obesity and diabetes pose a problem of absorption between body and environment. Drawing on ethnographic fieldwork carried out in Mumbai's home kitchens, metabolic disorder clinics, food companies, markets, and social services, he details the absorption of everything from snack foods and mangoes to insulin, stress, and pollutants. As these substances pass between the city and the body and blur the two domains, the onset and treatment of metabolic illness raise questions about who has the power to decide what goes into bodies and when food means life. Evoking metabolism as a condition of contemporary urban life and a vital political analytic, Solomon illuminates the lived predicaments of obesity and diabetes, and reorients our understanding of chronic illness in India and beyond.
A multidisciplinary analysis of the role of nutrition in generating hierarchical societies and cultivating a global epidemic of chronic diseases.
This book acts as a kind of "prequel" to Beyond Metabolism. In Understanding Metabolism Scott Abel discusses the truth about metabolic damage, the truth about calorie counting and calorie math, and what will and what won't lead to a healthy, robust metabolism and a fast metabolism. Learn about: * What realistic protein needs are if you're weight training. * Why diets fail when they don't take metabolism into account. * What causes metabolic damage, and the reality of repairing metabolic damage or healing a broken metabolism. * The truth about cardio, and why more cardio can make you fat. * How less exercise can lead to a faster metabolism. * Why the current "calorie-burning" focus of exercise is flawed and ineffective for optimal metabolic function and weight loss. * What kinds of exercises and training is best for an optimized metabolism. * Is caffeine okay? What about artificial sweeteners? Should I be aware of gluten? The book also has in-depth discussions of current trends like Paleo Dieting, the DNA Diet, and more. Learn the proper diet for a fast metabolism and health, longterm metabolic function. Learn what you need to know to lose weight... and KEEP it off! Get Understanding Metabolism now!
The HEP issue on Metabolic Control provides a state-of the art overview over both classical concepts and emerging areas in metabolism and associated disorders. In this context, metabolic control is highlighted at various levels of complexity ranging from transcriptional mechanisms in metabolic pathway control over metabolic communication routes in physiology and pathophysiology to current treatment modalities and options in metabolic disorders, including type 2 diabetes and obesity. Dedicated chapters by leading experts in their fields provide a concise overview over important areas in metabolic research at a molecular level, including the role of the central nervous system in metabolism, inflammation and metabolism, pancreatic hormone signaling, brown adipose tissue, and therapeutic concepts.
It is increasingly evident that the conventional scientific approach to economic processes and related sustainability issues is seriously flawed. No economist predicted the current planetary crisis even though the world has now undergone five severe recessions primed by dramatic increases in the price of oil. This book presents the results of more than twenty years of work aimed at developing an alternative method of analysis of the economic process and related sustainability issues: it is possible to perform an integrated and comprehensive analysis of the sustainability of socio-economic systems using indicators and variables that have been so far ignored by conventional economists. The book’s innovative approach aims to provide a better framework with which we can face the predicaments of sustainability issues. It begins by presenting practical examples of the shortcomings of conventional economic analysis and examines the systemic problems faced when trying to use quantitative analysis for governance. In providing a critical appraisal of current applications of economic narratives to the issue of sustainability, the book presents several innovative concepts required to generate a post-Newtonian approach to quantitative analysis in the Musiasem approach. An empirical section illustrates the results of an analysis of structural changes in world and EU countries. Finally, the book, using the insight gained in the theoretical and empirical analysis, exposes the dubious quality of many narratives currently used in the sustainability debate. Overall, the performance of modern economies across different hierarchical levels of organization and across different disciplinary knowledge systems is fully analyzed and a more realistic measure of happiness and well-being is devised. The book should be of interest to researchers and students looking at the issue of sustainability within a variety of disciplines.
The inclusion of oncogene-driven reprogramming of energy metabolism within the list of cancer hallmarks (Hanahan and Weinberg, Cell 2000, 2011) has provided major impetus to further investigate the existence of a much wider metabolic rewiring in cancer cells, which not only includes deregulated cellular bioenergetics, but also encompasses multiple links with a more comprehensive network of altered biochemical pathways. This network is currently held responsible for redirecting carbon and phosphorus fluxes through the biosynthesis of nucleotides, amino acids, lipids and phospholipids and for the production of second messengers essential to cancer cells growth, survival and invasiveness in the hostile tumor environment. The capability to develop such a concerted rewiring of biochemical pathways is a versatile tool adopted by cancer cells to counteract the host defense and eventually resist the attack of anticancer treatments. Integrated efforts elucidating key mechanisms underlying this complex cancer metabolic reprogramming have led to the identification of new signatures of malignancy that are providing a strong foundation for improving cancer diagnosis and monitoring tumor response to therapy using appropriate molecular imaging approaches. In particular, the recent evolution of positron emission tomography (PET), magnetic resonance spectroscopy (MRS), spectroscopic imaging (MRSI), functional MR imaging (fMRI) and optical imaging technologies, combined with complementary cellular imaging approaches, have created new ways to explore and monitor the effects of metabolic reprogramming in cancer at clinical and preclinical levels. Thus, the progress of high-tech engineering and molecular imaging technologies, combined with new generation genomic, proteomic and phosphoproteomic methods, can significantly improve the clinical effectiveness of image-based interventions in cancer and provide novel insights to design and validate new targeted therapies. The Frontiers in Oncology Research Topic “Exploring Cancer Metabolic Reprogramming Through Molecular Imaging” focusses on current achievements, challenges and needs in the application of molecular imaging methods to explore cancer metabolic reprogramming, and evaluate its potential impact on clinical decisions and patient outcome. A series of reviews and perspective articles, along with original research contributions on humans and on preclinical models have been concertedly included in the Topic to build an open forum on perspectives, present needs and future challenges of this cutting-edge research area.