Download Free Between Theory And Clinic The Contribution Of Neuroimaging In The Field Of Consciousness Disorders Book in PDF and EPUB Free Download. You can read online Between Theory And Clinic The Contribution Of Neuroimaging In The Field Of Consciousness Disorders and write the review.

The amount of patients surviving severe brain injury has gradually increased over these last decades thanks to the development of intensive care. These patients either recover quickly from coma or go through prolonged disorders of consciousness such as vegetative state/unresponsive wakefulness syndrome (VS/UWS) or minimally conscious state (MCS). While patients in a minimally conscious state are to some extent aware of themselves and the environment, and show fluctuating but reproducible signs of consciousness, patients in a vegetative state/unresponsive wakefulness syndrome are awake but only show reflexive behaviors. These patients are unable to communicate and present vigilance fluctuation, sensory deficits as well as severe motor and language impairments. Even though behavioral assessment currently remains the gold standard for diagnosis, a number of studies highlights the difficulty in making the distinction between conscious and unconscious patients based on clinical examinations and show a misdiagnosis rate as high as 40%. Misdiagnosis can nevertheless have serious consequences on patient’s management, medically but also ethically (i.e., regarding end-of-life decision). The emergence of functional neuroimaging techniques (such as positron emission tomography – PET and functional magnetic resonance imaging – fMRI) opened new opportunities to study brain activity in patients with disorders of consciousness (DOC). Recent neuroimaging tools have brought new understandings on how the brain functions after coma, and how these tools can complement bedside assessment by improving diagnosis and prognosis of DOC patients. Indeed, we know now that most patients in VS/UWS present partial activation of sensory networks and impaired functional connectivity contrary to patients in MCS. The reemergence of thalamo-cortical connections has also been associated with recovery of consciousness; whereas, thalamic atrophy has been associated to chronic DOC. Recent findings have also stressed the interest of neuroimaging in the management and the treatment of these patients. fMRI has been used as brain computer interfaces to detect consciousness in unresponsive patients and to allow basic communication in minimally conscious patients. Neuroimaging techniques are also currently being used to examine the effects of potential therapy such as pharmacological medications (e.g., Amantadine or Zolpidem) and brain stimulations (e.g., transcranial direct current stimulation or repetitive transcranial magnetic stimulation).
The second edition of The Neurology of Consciousness is a comprehensive update of this ground-breaking work on human consciousness, the first book in this area to summarize the neuroanatomical and functional underpinnings of consciousness by emphasizing a lesional approach offered by the study of neurological patients. Since the publication of the first edition in 2009, new methodologies have made consciousness much more accessible scientifically, and, in particular, the study of disorders, disruptions, and disturbances of consciousness has added tremendously to our understanding of the biological basis of human consciousness. The publication of a new edition is both critical and timely for continued understanding of the field of consciousness. In this critical and timely update, revised and new contributions by internationally renowned researchers—edited by the leaders in the field of consciousness research—provide a unique and comprehensive focus on human consciousness. The new edition of The Neurobiology of Consciousness will continue to be an indispensable resource for researchers and students working on the cognitive neuroscience of consciousness and related disorders, as well as for neuroscientists, psychologists, psychiatrists, and neurologists contemplating consciousness as one of the philosophical, ethical, sociological, political, and religious questions of our time. - New chapters on the neuroanatomical basis of consciousness and short-term memory, and expanded coverage of comas and neuroethics, including the ethics of brain death - The first comprehensive, authoritative collection to describe disorders of consciousness and how they are used to study and understand the neural correlates of conscious perception in humans. - Includes both revised and new chapters from the top international researchers in the field, including Christof Koch, Marcus Raichle, Nicholas Schiff, Joseph Fins, and Michael Gazzaniga
The Cambridge Handbook of Consciousness is the first of its kind in the field, and its appearance marks a unique time in the history of intellectual inquiry on the topic. After decades during which consciousness was considered beyond the scope of legitimate scientific investigation, consciousness re-emerged as a popular focus of research towards the end of the last century, and it has remained so for nearly 20 years. There are now so many different lines of investigation on consciousness that the time has come when the field may finally benefit from a book that pulls them together and, by juxtaposing them, provides a comprehensive survey of this exciting field. An authoritative desk reference, which will also be suitable as an advanced textbook.
Plum and Posner's Diagnosis and Treatment of Stupor and Coma, 5th edition provides a comprehensive overview of the theory behind regulation of consciousness in humans, the mechanisms of loss of consciousness clinically, and the examination and diagnosis of the cause of loss of consciousness in patients. New sections provide the latest information on the treatment of comatose patients, brain death, recovery from structural coma, and the ethics of dealing with comatose patients.
This serial is firmly established as an extensive documentation of the advances in contemporary brain research. Each volume presents authoritative reviews and original articles by invited specialists.This volume concentrates on coma and consciousness science. presenting articles from leading figures in the area on the clinical and ethical implications of work in this field. The book provides a thorough review of the various aspects of coma science from a review of the concepts, questioning of recent advances, case studies, through to where research in the field is heading. - Provides the reader with a unique overview of all aspects of new advances in coma science - Broad focus with contributions by the top scientists worldwide in the respective disciplines
Fully updated and revised according to student feedback, the sixth edition of Mayo Clinic Medical Neurosciences: Organized by Neurologic System and Level provides a systematic approach to anatomy, physiology, and pathology of the nervous system inspired by the neurologist's approach to solving clinical problems. This volume has 4 sections: 1) an overview of the neurosciences necessary for understanding anatomical localization and pathophysiologic characterization of neurologic disorders; 2) an approach to localizing lesions in the 7 longitudinal systems of the nervous system; 3) an approach to localizing lesions in the 4 horizontal levels of the nervous system; and 4) a collection of clinical problems. This book provides the neuroscience framework to support the neurologist in a clinical setting and is also a great resource for neurology and psychiatry board certifications. This is the perfect guide for all medical students and neurology, psychiatry, and physical medicine residents at early stages of training. New to This Edition - A chapter devoted to multiple-choice questions for self-assessment - Discussion of emerging concepts in molecular, cellular, and system neurosciences - New chapters on emotion and consciousness systems - Incorporation of new discoveries in neuroimaging and an appendix for tables of medications commonly used to treat neurologic disorders
Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme
An up-to-date, superbly illustrated practical guide to the effective use of neuroimaging in the patient with sleep disorders. The only book to date to provide comprehensive coverage of this topic. A must for all healthcare workers interested in understanding the causes, consequences and treatment of sleep disorders.
Brain dysfunction is a major clinical problem in intensive care, with potentially debilitating long-term consequences for post-ICU patients of any age. The resulting extended length of stay in the ICU and post-discharge cognitive dysfunction are now recognized as major healthcare burdens. This comprehensive clinical text provides intensivists and neurologists with a practical review of the pathophysiology of brain dysfunction and a thorough account of the diagnostic and therapeutic options available. Initial sections review the epidemiology, outcomes, relevant behavioral neurology and biological mechanisms of brain dysfunction. Subsequent sections evaluate the available diagnostic options and preventative and therapeutic interventions, with a final section on clinical encephalopathy syndromes encountered in the ICU. Each chapter is rich in illustrations, with an executive summary and a helpful glossary of terms. Brain Disorders in Critical Illness is a seminal reference for all physicians and neuroscientists interested in the care and outcome of severely ill patients.