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The Routledge International Encyclopedia of Queer Culture covers gay, lesbian, bisexual, transgender and queer (GLBTQ) life and culture post-1945, with a strong international approach to the subject.The scope of the work is extremely comprehensive, with entries falling into the broad categories of Dance, Education, Film, Health, Homophobia, the Int
A full description of the clinical aspect and pathology of the disease, with a discussion of current treatment. This updated edition includes five new chapters: endocrinal brucellosis, difficulties in diagnosis and management, HIV and brucellosis, bioterrorism and brucellae, and spondylitis with neurobrucellosis. The book presents a complete, up-to-date picture of the disorder and will appeal to clinicians, students, researchers and also to veterinarians.
This book equips young immunologists and health professionals with a clear understanding of the fundamental concepts and roles of co-signal molecules and in addition presents the latest information on co-stimulation. The first part of the book is devoted to co-signal molecules and the regulation of T cells. Following an initial overview, subsequent chapters examine each co-signal molecule in turn and discuss the mechanisms by which co-signal molecules regulate the different types of T cell. The second part covers various clinical applications, including in autoimmune disease, neurological disorders, transplantation, graft-versus-host disease, and cancer immunotherapy. To date, co-stimulation blockade and co-inhibition blockade have shown beneficial effects and many additional clinical trials targeting co-signal molecules are ongoing. The mechanisms underlying these successful treatments are explained and the future therapeutic potential in the aforementioned diseases is evaluated. Co-signal Molecules in T Cell Activation will be a valuable reference guide to co-stimulation for basic and clinical researchers in the fields of both immunology and pharmaceutical science.
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As a collection of papers that includes material presented at the 2008 International Congress for Plant Pathology, this text features research right at the leading edge of the field. The latest findings are particularly crucial in their implications for fruit production; an important market sector where in some areas up to 50 per cent of the crop can be lost after harvest. While post-harvest fruit treatments with fungicides are the most effective means to reduce decay, rising concerns about toxicity have led to the development of alternative approaches to disease control, including biological methods, the subject of three chapters of this book. With several new techniques requiring modification of current post-harvest practices, it is more important than ever to stay abreast of the latest information. Other chapters deal with the mechanisms of host fruit and vegetable resistance, fungal pathogenicity factors and their relationship with the host response, and a number of subjects related to disease assessments before harvest as well as their relationship to the postharvest treatment of fruits and vegetables. The book also includes several useful case studies of crops such as kiwifruit and peaches, where different approaches at the pre- and post-harvest levels are combined to good effect. With food production issues gaining an ever higher profile internationally, this text makes an important contribution to the debate.