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This issue will provide a current update on diagnosis, treatment, and management of children with being hematological disorders. Dr. Callaghan has put together a comprehensive issue with clinical reviews written by top experts in the field. Articles are devoted to the following topics: Hemophilia; Sickle cell acute chest; Sickle cell drugs; Sickle cell gene therapy; Sickle cell menses and pain; Pediatric DVT; Atypical HUS; von Willebrand Disease; Female bleeding; Functional platelet disorders; Hemolytic anemia; Advocacy in hematology; ITP; and Acquired aplastic anemia. Readers will come away with the current clinical information they need to improve clinical outcomes.
This issue will provide a current update on diagnosis, treatment, and management of children with benig hematological disorders. Dr. Callaghan has put together a comprehensive issue with clinical reviews written by top experts in the field. Articles are devoted to the following topics: Hemophilia; Sickle cell acute chest; Sickle cell drugs; Sickle cell gene therapy; Sickle cell menses and pain; Pediatric DVT; Atypical HUS; von Willebrand Disease; Female bleeding; Functional platelet disorders; Hemolytic anemia; Advocacy in hematology; ITP; and Acquired aplastic anemia. Readers will come away with the current clinical information they need to improve clinical outcomes.
With collaboration of Dr. Bonita Stanton, Drs. Coppes and Fisher-Owens have created a current issue that looks at oral health in children, with a much needed update in the literature for pediatricians. Top experts have contributed clinical reviews on the following topics: Oral Health and Development; Infant Oral Health and the Influence of Habits; Prevention of tooth decay; Fluoride; Caries; Disparities in Children’s Oral Health (including Oral Health of Native Children); Children with Special Health Care Needs; Orthodontics; Oral Manifestations of Systemic Disease (specific to pediatrics and life course); Soft Tissue; Trauma; The Role of Primary Care Physicians (pediatricians and others) in Prevention Oral Disease; and Oral Health Care/Policies. Pediatricians will come away with the current clinical recommendations they need to improve oral health in children.
Clinical decision making in the emergency department; Recent advances in the recognition, evaluation and management of pediatric sepsis; Evaluation and management of the adult patient presenting to a pediatric ED; Critical care in the pediatric ED; Point of care testing in the ED: Implications, impact and future directions; Child abuse and conditions that mimic them; Indications and interpretation of common investigations/tests in the ED; Recent advances in pediatric concussion and mild traumatic brain injury; Pediatric emergency care: Impact on healthcare and implications for policy; Clinical decision rules in the pediatric ED; Pediatric urgent care: The good, the bad and the ugly; Advances in medical education and implications for the pediatric ED workforce; Quality and safety in pediatric ED; Optimizing resources and impact of lean processes on ED operations; Pediatric readiness and disaster management; Recent advances in technology and its applications to pediatric emergency care
With consultation of Dr. Bonita Stanton, Consulting Editor, Drs. Li and Higgins have secured experts in the field to provide clinical reviews on the latest updates in diagnosing and treating children with rheumatologic disease. The issue contains articles on the following topics: Approach to the Child with Joint Pain; What goes wrong that Leads to Rheumatic Disease; Juvenile Idiopathic Arthritis; Spondyloarthropathies; Systemic Arthritis; Systemic Lupus Erythematosus; Sjogren’s and Mixed CTD in Children and Adolescents; Idiopathic Inflammatory Myopathies in Children; Juvenile Scleroderma; Chronic Non-Infectious Osteomyelitis and Chronic Recurrent Multifocal Osteomyelitis; Non-Inflammatory Musculoskeletal Pain in Children or Pediatric Pain Syndromes; Complications of Immunosuppressive and Biologic Response Modifier Therapy; General Health Concerns and Fitness for the Child with Rheumatic Disease; Transition of Rheumatic Disease Care: Pediatric to Adult Care; and Advocacy for Children with Rheumatic Diseases. Readers will be able to utilize the information in the issue to improve outcomes in patients with rheumatologic disease.
The guest editors have compiled expert authors to provide current updates on the clinical management of inborn errors of metabolism. Authors have contributed clinical review articles on the following topics: Inborn errors of metabolism overview: pathophysiology, manifestations, evaluation, and management; Inborn errors of metabolism with acidosis: organic acidemias and defects of pyruvate and ketone body metabolism; Inborn errors of metabolism with hyperammonemia: urea cycle defects and related disorders; Inborn errors of metabolism with hypoglycemia: glycogen storage diseases and gluconeogenesis defects; Inborn errors of metabolism with myopathy: defects of fatty acid oxidation and carnitine transport; Inborn errors of metabolism with seizures: defects of glycine and serine metabolism and co-factor related disorders; Inborn errors of metabolism with hepatopathy: metabolism defects of galactose, fructose, and tyrosine; Inborn errors of metabolism with cognitive impairment: metabolism defects of phenylalanine, homocysteine and methionine, purine and pyrimidine, and creatine; Inborn errors of metabolism with movement disorders: defects in metal transport and neurotransmitter metabolism; Inborn errors of metabolism involving complex molecules: lysosomal and peroxisomal storage diseases; Inborn errors of metabolism with complex phenotypes: mitochondrial disorders and congenital disorders of glycosylation; and Newborn screening: history, current status, and future directions.
The topics in this issue represent the most current research areas of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Collaborative Pediatric Critical Care Research Network (CPCCRN). The CPCCRN is a national pediatric critical care research network that is charged with investigating the efficacy of treatment and management strategies to care for critically ill and injured children, as well as to better understand the pathophysiological basis of critical illness and injury in childhood. The proposed authors are past and present principal and co-investigators affiliated with the CPCCRN; the proposed topics represent the individual author’s area of clinical and research expertise. Each review article is an up-to-date review of the topic relevant to practicing clinicians and trainees in critical care medicine, with incorporation of the most recently published research findings pertinent to the topic, some of which may be the author’s own. The specific articles are devoted to the following topics: Cardiopulmonary resuscitation in pediatric and cardiac ICU; Approach to the critically ill pediatric trauma patient; Transfusion Decision Making in Pediatric Critical Illness; Pathophysiology and management of ARDS in children; Ventilator associate pneumonias in critically ill children; Mechanical ventilation and decision support in pediatric intensive care; Inflammation, pathobiology, phenotypes and sepsis: From meningococcemia to H1N1-MRSA, to Ebola; Immune paralysis in pediatric critical care; Molecular biology of critical illness; Sedation in pediatric critical illness; Delirium in pediatric critical illness; Challenges of drug development in pediatric intensive care; Potential of All Steroid Hormone Subclasses as Adjunctive Treatment for Sepsis; Morbidity: Changing the outcome paradigm; and End-of-Life and Bereavement Care in Pediatric Intensive Care Units.
Dr. Aranda is an top expert in the area of pharmacology in the pediatric population. His issue has knowledgeable authors presenting clinical reviews on a wide variety of topics, from "hot areas " of drug therapy to drug abuse in children as well as current areas of debate in neonatal drug therapy. Articles are devoted to the following topics: New and Current Drug Therapies For Asthma In Children; Psychopharmacology Of Bipolar Disorders in Children and Adolescents; Designer Drug Abuse in School Children; Dietary Supplements in Children; Anticoagulant Therapies in Children; New Antimicrobials for Gram-Positive Infections in Children; Probiotics in Newborns And Children; Anticonvulsant Therapies in Newborns and Children; Immunomodulator Drug Therapies in Inflammatory Bowel Diseases in Children; Non-Steroidal Anti-Inflammatory Drugs in Newborns and Children; Metformin Use in Pre-Diabetic Children and Adolescents; Problems in Drug Dosing of Obese Children; Inhaled Drugs and Systemic Steroids for Bronchopulmonary Dysplasia; Antifungal Drugs in Newborns and Children; Antiviral Drugs In Newborns and Children; and Development of Drug Therapies for Newborns and Children. Readers will come away with the latest clinical information to help inform them when diagnosing and prescribing for children.
Blood transfusions are an important part of hematologic care. This issue of Hematology/Oncology Clinics will focus on transfusion medicine and will include articles on: RBC Transfusions: Conclusions from Clinical Trials and the Establishment of Evidence-based Guidelines for Adults, Platelet Transfusions: Conclusions from Clinical Trials and the Establishment of Evidence- and/or Experience-based Guidelines for Adults, Use and Overuse of Plasma Products: Establishment of Evidence- and/or Experience-based Guidelines for Plasma Transfusion in Adults, Stem Cell Mobilization/Collection: Coordination Between Hem/Onc, Transplant, and Transfusion Services, Management of Patients with Sickle Cell Disease Using Transfusion Therapy: Guidelines and Complications, and many more exciting articles.
Like many other medical and health-related professions, the speech-language pathology and audiology professions have been responding to the changes in the ways in which healthcare is delivered. These changes are occurring at the federal and state levels due to changes in legislative and regulatory policies. To this end and as a result of reports from the World Health Organization (2010, 2011, 2013) and the Institute of Medicine (2000, 2001, 2015), healthcare professionals are now addressing healthcare service delivery within an interprofessional, collaborative practice and patient outcomes context. This volume of Pediatric Clinics will present articles that address clinical care to a variety of pediatric speech and language clinical populations. While it will be the intent of each piece to address interprofessional perspectives of care, the opening and closing pieces, respectively, will introduce and then synthesize, all of the articles into a cogent volume. Articles are devoted to the following topics: The Journey to Interprofessional Practice: Are We There Yet; Late Talkers: Why the ‘Wait and See’ Approach is Outdated; A Pediatrician’s Guide to Cleft Palate Speech and Non-Cleft Causes of Velopharyngeal Insufficiency (VPi); Supporting Children with Autism and Their Families: A Model for Interprofessional Practice; Feeding Problems in Infants and Children: Assessment and Etiology; A Multidisciplinary Team Approach to the Differential Diagnosis of Children with Communication Disorders; Open Up and Let Us In: An Interdisciplinary Approach to Oral Health; Otitis Media: Beyond the Examining Room; Clinical Perspectives on Pre-Literacy Development in Young Children; Using the ICF Framework to Achieve Interprofessional Functional Outcomes for Young Children: A Speech-Language Pathology Perspective; Developmental Care of the Pre-Term Infant: From NICU Through High-Risk Infant Follow Up; Interprofessional Collaborative Practice: What That Means for Early Intervention Service Delivery; The Role of the Speech-Language Pathologist in Creating a Model for Interprofessional Practice in an Ambulatory Care Clinic; and Identification of Speech and Language Delays in Young Children: An Important Collaborative Role for the Pediatrician.