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The AIDS epidemic in Sub-Saharan Africa continues to affect all facets of life throughout the subcontinent. Deaths related to AIDS have driven down the life expectancy rate of residents in Zambia, Kenya, and Uganda with far-reaching implications. This book details the current state of the AIDS epidemic in Africa and what is known about the behaviors that contribute to the transmission of the HIV infection. It lays out what research is needed and what is necessary to design more effective prevention programs.
HIV/AIDS is a catastrophe globally but nowhere more so than in sub-Saharan Africa, which in 2008 accounted for 67 percent of cases worldwide and 91 percent of new infections. The Institute of Medicine recommends that the United States and African nations move toward a strategy of shared responsibility such that these nations are empowered to take ownership of their HIV/AIDS problem and work to solve it.
Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.
This is the eBook version of the printed book. This Element is an excerpt from AIDS: Taking a Long-Term View (9780132172592) by the aids2031 Consortium. Available in print and digital formats. What we’ve learned about building prevention programs that can dramatically reduce the worldwide impact of AIDS. If the picture of AIDS is to be substantially more favorable in 2031 than it is today, markedly greater progress is required in preventing new infections. Given the rate at which the pandemic is outpacing programmatic scale-up, incremental improvements won’t suffice. Prevention programs will need to have radically greater impact....
This paper presents findings of the Third Review under the poverty reduction and growth facility arrangement for Kenya. The sharp spending increase budgeted for 2007/08 could exert pressures on domestic prices and compromise project quality, but the authorities are taking steps to mitigate these risks. Authorities are committed to fully implementing the budget only if nonfood inflation remains low and project quality is maintained. Some aspects of governance have improved, but challenges remain. Structural reforms in public financial management need to be broadened and financial sector reforms accelerated.
Globally, women of reproductive age face two overlapping issues that have a significant impact on their health and well-being: unintended pregnancy and sexually transmitted infections (STIs), including HIV. A growing body of research indicates that the majority of women across geographies, ages, racial and ethnic backgrounds would prefer a multipurpose prevention technology (MPT) that combines protection against pregnancy and HIV/STIs versus individual products for contraception and disease prevention. Currently, male and female condoms are the only available MPTs. A wider range of MPT options will help women select methods that they are less apt to discontinue, as well as increase uptake by first-time users. A number of MPT candidates – intravaginal rings (IVRs), oral tablets, vaginal fast dissolving inserts (FDIs), implants, injectables and microarray patches (MAPs) are in various stages of development. The goal of this Research Topic is to invigorate continued development on MPTs by providing the most up-to-date research on specific products in development, identifying research gaps related to the field overall, and prepare for introduction into programs and healthcare systems. Our broad approach will cover formulation science, clinical trials, sociobehavioral research, and implementation science to present the latest thinking in all areas of MPT development from “bench to bedside.”