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Harry F.W. Buchholtz married Margaret Copley July 16, 1912 at Manhattan, Kansas. Includes families of Burrow, Sibbett, Truby, DeWolf, Brewster, Fricke, Hookway, Billington, Kimber.
The Genealogy Annual is a comprehensive bibliography of the year's genealogies, handbooks, and source materials. It is divided into three main sections. FAMILY HISTORIES-cites American and international single and multifamily genealogies, listed alphabetically by major surnames included in each book. GUIDES AND HANDBOOKS-includes reference and how-to books for doing research on specific record groups or areas of the U.S. or the world. GENEALOGICAL SOURCES BY STATE-consists of entries for genealogical data, organized alphabetically by state and then by city or county. The Genealogy Annual, the core reference book of published local histories and genealogies, makes finding the latest information easy. Because the information is compiled annually, it is always up to date. No other book offers as many citations as The Genealogy Annual; all works are included. You can be assured that fees were not required to be listed.
The newsmagazine of the New England Historic Genealogic Society.
A state-of-the-art primer on the role of pharmacological sciences in regenerative medicine, for advanced students, postdoctoral fellows, and researchers.
Animal life, now and over the past half billion years, is incredibly diverse. Describing and understanding the evolution of this diversity of body plans - from vertebrates such as humans and fish to the numerous invertebrate groups including sponges, insects, molluscs, and the many groups of worms - is a major goal of evolutionary biology. In this book, a group of leading researchers adopt a modern, integrated approach to describe how current molecular genetic techniques and disciplines as diverse as palaeontology, embryology, and genomics have been combined, resulting in a dramatic renaissance in the study of animal evolution. The last decade has seen growing interest in evolutionary biology fuelled by a wealth of data from molecular biology. Modern phylogenies integrating evidence from molecules, embryological data, and morphology of living and fossil taxa provide a wide consensus of the major branching patterns of the tree of life; moreover, the links between phenotype and genotype are increasingly well understood. This has resulted in a reliable tree of relationships that has been widely accepted and has spawned numerous new and exciting questions that require a reassessment of the origins and radiation of animal life. The focus of this volume is at the level of major animal groups, the morphological innovations that define them, and the mechanisms of change to their embryology that have resulted in their evolution. Current research themes and future prospects are highlighted including phylogeny reconstruction, comparative developmental biology, the value of different sources of data and the importance of fossils, homology assessment, character evolution, phylogeny of major groups of animals, and genome evolution. These topics are integrated in the light of a 'new animal phylogeny', to provide fresh insights into the patterns and processes of animal evolution. Animal Evolution provides a timely and comprehensive statement of progress in the field for academic researchers requiring an authoritative, balanced and up-to-date overview of the topic. It is also intended for both upper level undergraduate and graduate students taking courses in animal evolution, molecular phylogenetics, evo-devo, comparative genomics and associated disciplines.
This volume provides the reader with an overview of the diverse functions of the RUNX family of genes. As highlighted in the introduction and several of the 29 chapters, humans and other mammals have three RUNX genes that are known to play specific roles in blood, bone and neuronal development. However, their evolutionary history has recently been traced back to unicellular organisms and their involvement in many well-known signaling pathways (Wnt, TGFb, Notch, Hippo) is indicative of a more general function in cell biology. Their documented roles in cell fate decisions include control of proliferation, differentiation, survival, senescence and autophagy. The pleiotropic effects of RUNX in development are mirrored in cancer, where RUNX genes can function as oncogenes that collaborate strongly with Myc family oncogenes or as tumour suppressor genes. In the latter role, they display hallmarks of both ‘gatekeepers’ that modulate p53 responses and ‘caretakers’ that protect the genome from DNA damage. Several chapters focus on the importance of these genes in leukemia research, where RUNX1 and CBFB are frequently affected by chromosomal translocations that generate fusion oncoproteins, while recent studies suggest wider roles for RUNX modulation in solid cancers. Moreover, RUNX genes are intimately involved in the development and regulation of the immune system, while emerging evidence suggests a role in innate immunity to infectious agents, including HIV. At the biochemical level, the RUNX family can serve as activators or repressors of transcription and as stable mediators of epigenetic memory through mitosis. Not surprisingly, RUNX activity is controlled at multiple levels, this includes miRNAs and a plethora of post-translational modifications. Several chapters highlight the interplay between the three mammalian RUNX genes, where cross-talk and partial functional redundancies are evident. Finally, structural analysis of the RUNX/CBFB interaction has led to the development of small molecule inhibitors that provide exciting new tools to decipher the roles of RUNX in development and as targets for therapy. This volume provides a compendium and reference source that will be of broad interest to cancer researchers, developmental biologists and immunologists.
This book introduces Planctomycetes bacteria and deals in detail with their unusual structure, physiology, genomics and evolutionary significance. It is a definitive summary of recent knowledge of this important distinctive group of bacteria, microorganisms which challenge our very concept of the bacterium. Planctomycetes, and their relatives within the PVC superphylum of domain Bacteria, including verrucomicrobia and chlamydia, challenge our classical concept of the bacterium and its modes of life and provide new experimental models for exploring evolutionary cell biology and the full diversity of how living cells can be organized internally. Unique among bacteria, they include species possessing cells with intracellular membrane-bounded compartments and a peptidoglycan-less cell wall, and bacteria such as the anammox organisms performing unique anaerobic ammonium oxidation significant for global nitrogen cycle.