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This comprehensive review on neem is an excellent collation of observations and research efforts by botanists, taxonomists and medical practitioners and will be of interest to everyone with an interest involved in medicinal and aromatic plant research.
The most comprehensive and best illustrated treatment of the fascinating tropical neem tree (Azadirachta indica) and its unique substances. The extracts from the neem tree have an enormously broad range of applications. The main substance azadirachtin, a tetranortriterpenoid, influences the hormone system of insects, exerting thereby a pesticidal effect. Feeding activity, reproduction and flying ability of insects are also affected. It is biologically degradable and can be easily extracted from the seeds of the tree. Other important uses of neem tree products are: - antifertility and population control - cure of human diseases - manure and nitrification inhibitors - feeds for domestic animals - soap production With its exhaustive treatment of the neem tree and closely related plants, this book provides us with an impressive example of the varied uses of renewable resources.
Because of increasing antibiotic resistance, stronger antibiotics are reserved for serious active infection, paving the way for a greater use of herbal antibiotics. This book helps dentists in implementing safe and effective natural medicine therapies to complement the current practice guidelines. Oral diseases continue to be a major health problem world-wide. Oral health is integral to general well-being and relates to the quality-of-life that extends beyond the functions of the craniofacial complex. The standard Western medicine has had only limited success in the prevention of periodontal disease and in the treatment of a variety of oral diseases. The dentist needs to be more informed regarding the use, safety and effectiveness of the various traditional medicines and over-the-counter products. Herbal extracts have been used in dentistry for reducing inflammation, as antimicrobial plaque agents, for preventing release of histamine and as antiseptics, antioxidants, antimicrobials, antifungals, antibacterials, antivirals and analgesics. They also aid in healing and are effective in controlling microbial plaque in gingivitis and periodontitis and thereby improving immunity. The 26 chapters in this unique book explore all the measures to utilize the natural oral care obtained from plants, animals and mineral drugs for dental care.
The chemicals from plant sources, generally termed as phytochemicals, play an important role in acceptance or rejection of the plant by the pests as they could be distasteful or toxic on one hand or on the other hand specialist herbivores have the capability to feed on many such chemicals, as they are able to process these natural products in a manner that is beneficial to them. In the wake of increasing environmental degradation due to burgeoning synthetic chemicals, there has been a process going on to rediscover the usefulness of plants and herbs and a continued effort for more than 2 decades has been to study the green products for cures for several ailments and pest management. In fact, according to Indian Medicinal Plants: A Sectoral Study, the global trade for medicinal plants amounts to about US $ 60 billion and the world demand continues to grow at the rate of 7 per cent per annum. Although many such plants are known in literature, neem has been one of trees with mani-fold virtues. Indian neem tree, Azadirachta indica A. Juss, which is a large evergreen tree, is an outstanding example among plants that has been subject matter of numerous scientific studies concerning its utilization in medicine, industry and agriculture. So far neem preparations have been evaluated against more than 500 species of insects and more than 400 hundred are reported to be susceptible at different concentrations.
Covers the structurally diverse secondary metabolites of medicinal plants, including their ethnopharmacological properties, biological activity, and production strategies Secondary metabolites of plants are a treasure trove of novel compounds with potential pharmaceutical applications. Consequently, the nature of these metabolites as well as strategies for the targeted expression and/or purification is of high interest. Regarding their biological and pharmacological activity and ethnopharmacological properties, this book offers a comprehensive treatment of 100 plant species, including Abutilon, Aloe, Cannabis, Capsicum, Jasminum, Malva, Phyllanthus, Stellaria, Thymus, Vitis, Zingiber, and more. It also discusses the cell culture conditions and various strategies used for enhancing the production of targeted metabolites in plant cell cultures. Secondary Metabolites of Medicinal Plants: Ethnopharmacological Properties, Biological Activity and Production Strategies is presented in four parts. Part I provides a complete introduction to the subject. Part II looks at the ethnomedicinal and pharmacological properties, chemical structures, and culture conditions of secondary metabolites. The third part examines the many strategies of secondary metabolites production, including: biotransformation; culture conditions; feeding of precursors; genetic transformation; immobilization; and oxygenation. The last section concludes with an overview of everything learned. -Provides information on cell culture conditions and targeted extraction of secondary metabolites confirmed by relevant literature -Presents the structures of secondary metabolites of 100 plant species together with their biological and pharmacological activity -Discusses plant species regarding their distribution, habitat, and ethnopharmacalogical properties -Presents strategies of secondary metabolites production, such as organ culture, pH, elicitation, hairy root cultures, light, and mutagenesis Secondary Metabolites of Medicinal Plants is an important book for students, professionals, and biotechnologists interested in the biological and pharmacological activity and ethnopharmacological properties of plants.
This book describes the sequencing efforts for Neem (Azadirachta indica A. Juss), one of the most versatile tropical evergreen tree species. The neem tree is a source of various natural products, including the potent biopesticide azadirachtin and limonoids, which have a broad spectrum of activity against insect pests and microbial pathogens. To identify genes and pathways in neem, three neem genomes and several transcriptomes are studied using next-generation sequencing technologies. Neem has been extensively used in Ayurveda, Unani and homoeopathic medicine and is often referred to as the ‘village pharmacy’ by natives due to its wealth of medicinal properties. Besides the description of the genome, this book discusses the neem microbiome and its role in the production of neem metabolites like salanin, nimbin and exopy-azadirachtin under in vitro conditions. It also highlights cell and tissue culture using various neem explants including the leaf, root, shoot, cambium, etc.
The role of Bioactive Dietary Factors and Plant Extracts in Preventive Dermatology provides current and concise scientific appraisal of the efficacy of foods, nutrients, herbs, and dietary supplements in preventing dermal damage and cancer as well as improving skin health. This important new volume reviews and presents new hypotheses and conclusions on the effects of different bioactive foods and their components derived particularly from vegetables, fruits, and herbs. Primary emphasis is on treatment and prevention of dermal damage focusing on skin cancers with significant health care costs and mortality. Bioactive Dietary Factors and Plant Extracts in Preventive Dermatology brings together expert clinicians and researchers working on the different aspects of supplementation, foods, and plant extracts and nutrition and skin health. Their expertise provides the most current knowledge in the field and will serve as the foundation for advancing future research.
This book will cover both the evidence for biofilms in many chronic bacterial infections as well as the problems facing these infections such as diagnostics and treatment regimes. A still increasing interest and emphasis on the sessile bacterial lifestyle biofilms has been seen since it was realized that that less than 0.1% of the total microbial biomass lives in the planktonic mode of growth. The term was coined in 1978 by Costerton et al. who defined the term biofilm for the first time.In 1993 the American Society for Microbiology (ASM) recognised that the biofilmmode of growth was relevant to microbiology. Lately many articles have been published on the clinical implications of bacterial biofilms. Both original articles and reviews concerning the biofilm problem are available.
This book is designed to provide pharmacologists and researchers of natural products a comprehensive review of 200 medicinal plants, their vernacular names in various languages and their medicinal uses around the world, and in some cases, a historical perspective. Chemical constituents of each plant with the putative active constituent, and available up to date pharmacological studies (until 2017 on PubMed) with each medical activity explored and its relationship with traditional uses, are described for each plant. Any variations in chemical constituents and their effects on pharmacological studies outcome have been highlighted. All clinical trials conducted, with sufficient details, have been included. Nationalities and racial identities of participants of clinical trials are identified to impress upon the social, cultural and dietary influences on the clinical outcomes. Toxicity studies and potential interactions with prescribed drugs, and full spectrum of references are included.