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This book presents the state of the art in atrophic rhinitis and analyses its specific characteristics in non-allergic rhinitis. Little has been written on this condition, which represents a topical issue in modern clinical practice, and as such many clinicians tend to underestimate its impact on patients’ quality of life. This book covers the definition, aetiology, clinical presentation, diagnosis and management, providing specialists with a better understanding of this condition and of the treatment options. It describes in detail the latest diagnostic tools, such as the innovative computational fluid-dynamics studies, nasal cytology, trigeminal stimulation tests, olfactometry, subjective questionnaires, with a focus on the psychological aspects, which have not yet been systematically investigated. Further, it discusses therapeutic strategies, both medical and surgical, reviewing the literature, from the first historical procedures to recent conservative techniques, such as lateral nasal wall reconstruction with various materials, and septal perforation repair. Illustrating all the options currently available, the book is an invaluable resource, not only for otolaryngologists, but also for plastic surgeons, clinical allergists and rheumatologists.
Polymicrobial diseases, those involving more than one etiologic agent, are more common than is generally realized and include respiratory diseases, gastroenteritis, conjunctivitis, keratitis, hepatitis, periodontal diseases, multiple sclerosis, genital infections, intra -- abdominal infections, and pertussis.
Revised and updated, this highly acclaimed volume is a complete, current, and practical guide to the diagnosis and treatment of allergic disorders. This comprehensive yet concise reference will remain the first choice for residents and practitioners who need guidance to identify an allergy, confirm a diagnosis, or find effective therapies.
The prevalence of allergic diseases has increased dramatically over recent decades, both in terms of the number of sufferers and the number of allergies. This is a trend that has frequently been referred to as 'the epidemic of the 21st century'. As described in ancient texts, allergies have been known for over 2,000 years, but the term 'allergy' was only coined at the beginning of the 20th century when doctors began to understand their pathophysiological basis. This book presents a detailed and varied historical overview of the field of allergology. Beginning with insights on allergy from antiquity to the 20th century and the development of the associated terminology, it compiles historical reflections on the understanding of the most common allergic diseases. Important milestones in the discovery of mechanisms of allergy are described, followed by historical accounts of the detection of allergens such as pollen, dust mites, peanuts and latex, and of environmental influences such as pollution and the relationship between farmers and their environment. Several chapters illustrate the progress made in allergy management to date. Particular highlights of this book are the personal reflections of and interviews with a number of pioneers of allergy, including F. Austen, J. Bienenstock, K. Blaser, A. de Weck, A.W. Frankland, K. Ishizaka, and many more. Concluding with portrayals of allergy societies and collections, as well as being supplemented by two films, this book represents a veritable treasure trove of fascinating and richly illustrated information. Not only researchers, physicians and medical historians, but also students and even non-scientists will find History of Allergy a scientific adventure well worth reading.
Diseases of the Sinuses: A Comprehensive Textbook of Diagnosis and Treatment, 2nd Edition, offers the definitive source of information about the basic science of the sinuses and the clinical approach to sinusitis. Since the widely praised publication of the first edition, understanding of sinus disease has changed dramatically, mainly as a result of recent developments and new discoveries in the field of immunology. This updated and expanded edition is divided into sections addressing, separately, the pathogenesis, clinical presentation, medical and surgical management of acute and chronic rhinosinusitis. Special entities such as autoimmune-related sinusitis, allergy and sinusitis, and aspirin-exacerbated respiratory disease are discussed in separate chapters. The role of immunodeficiency is also addressed. The management section has been fully updated to incorporate new medical modalities and surgical procedures. Developed by a distinguished group of international experts who share their expertise and insights from years of collective experience in treating sinus diseases, the book will appeal to anyone who has an interest in sinus disease, including both physicians and allied health professionals. Internists, pediatricians, allergists, otolaryngologists and infectious disease specialists will find the book to be an invaluable, comprehensive reference. Physician assistants and nurse practitioners who work with specialists who treat sinus disease will also benefit from the book.
Incidence of invasive fungal sinusitis has been increasing over the years. The understanding of its pathophysiology has improved with newer serological tests and diagnostic methods helping in earlier diagnosis and reducing patient morbidity. It was believed earlier that invasive fungal sinusitis is seen only in immune compromised patients but clinical reports suggest otherwise. More anti-fungal drugs are being added to improve incidence of patient survival. This book aims to compile all practical information about invasive fungal sinusitis into a single volume. Therefore, busy clinicians would not have to perform exhaustive literature studies to diagnose invasive fungal sinusitis. The book aims to provide an overview of diseases which could be mistaken for invasive fungal sinusitis and discuss how the management is different. Book sections consist of clinical, microbiological, serological, pathological, radiological and pharmacological features of the disease and its management. Each section is important in today’s context as it dynamically alters the management of the patient. Early clinical suspicion and rapid microbiological, pathological and radiological diagnosis with aggressive treatment with surgical debridement and medical therapy leads to favorable outcomes.
The Comprehensive Sourcebook of Bacterial Protein Toxins, Fourth Edition, contains chapters written by internationally known and well-respected specialists. This book contains chapters devoted to individual toxins, as well as chapters that consider the different applications of these toxins. Considerable progress has been made in understanding the structure, function, interaction and trafficking into cells, as well as mechanism of action of toxins. Bacterial toxins are involved in the pathogenesis of many bacteria, some of which are responsible for severe diseases in human and animals, but can also be used as tools in cell biology to dissect cellular processes or used as therapeutic agents. Novel recombinant toxins are already proposed in the treatment of some diseases, as well as new vaccines. Alternatively, certain toxins are also considered as biological weapons or bioterrorism threats. Given the multifaceted aspects of toxin research and the multidisciplinary approaches adopted, toxins are of great interest in many scientific areas from microbiology, virology, cell biology to biochemistry and protein structure. This new edition is written with a multidisciplinary audience in mind and contains 5 new chapters that reflect the latest research in this area. Other chapters have been combined, deleted and fully revised as necessary to deliver relevant and valuable content. - Descriptions of relevant toxins as well as representative toxins of the main bacterial toxin families to allow for a better comparison between them - Focused chapters on toxin applications and common properties or general features of toxins
The ninth and latest edition of this comprehensive guide to swine diseases and production information features extensively revised and updated chapters on physical examination and diagnosis, various viral and bacterial diseases (including several new disease chapters), other miscellaneous conditions and veterinary practice. Notwithstanding the title, this classic book covers not only infectious diseases of swine, but also includes chapters dealing with therapeutics, surgery and anesthesia, animal welfare, nutrition, and the provision of veterinary services. Diseases of Swine, 9e is divided into 5 sections: Physical Examination and Diagnosis, Viral Diseases, Bacterial Diseases, Miscellaneous Conditions, and Veterinary Practice. The ninth edition reflects changes to our knowledge and management of swine diseases and addresses recent research and progress in the field. More than 100 distinguished and widely recognized contributing authors bring the latest information to this new edition. With liberal use of illustrative materials--275 high quality illustrations and black and white photographs and more than a dozen color images--Diseases of Swine, 9e offers unparalleled coverage and is an indispensable reference for the veterinary practitioner, from the new graduate to the seasoned swine practitioner. This new edition is an indispensable and up-to-date reference text that belongs on the shelf of anyone interested in swine production, health and management.
The aim of this book is to harmonize the field of Otorhinolaryngology, Head and Neck Surgery and its interdisciplinary subjects within the European Community; to present the state of the art in the field and to give standards for diagnostic and therapeutic procedures. The book includes sections titled Head and Neck, Larynx and Trachea, Nose and Paranasal Sinuses, Oral Cavity and Oropharynx, and Otology and Neurotology. It also covers such topics as patient evaluation and treatment, basic surgical procedures, as well as more conservative approaches. The book is authored by renowned experts throughout Europe, and features a layout that facilitates quick and easy retrieval of information.