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It is estimated that around 15% of the population suffer from atopic dermatitis or eczematous disorders at some point in their lifetime, causing a significant percentage of visits to dermatologists, primary care physicians, and allergists. Despite much current research interest, the pathophysiology of these disorders and their optimum treatment rem
This book presents the state of the art in research into atopic dermatitis, or atopic eczema, and provides numerous effective practical management recommendations that are grounded in the immense clinical experience of the author. A scientific evidence-based approach to the subject is adopted, progressing from clinical symptoms in different disease stages, molecular genetics, and pathophysiology through to treatment and prevention. All aspects of patient management are covered, including diagnostics, avoidance strategies, emollient therapy, and acute treatment of eczema and itch. Diverse special therapeutic approaches are discussed, ranging from glucocorticoids, topical calcineurin inhibitors, and antimicrobial therapy through to UV therapy, allergen-specific immunotherapy, systemic immunosuppressive therapy, and emerging options. Environmental influences are considered, and there is a focus on the whole human being, with attention to psychosocial aspects of the disease and the benefit of educational programs such as “eczema schools”. Atopic Dermatitis will be invaluable for dermatologists, allergists, pediatricians, and general practitioners and informative for other interested persons and sufferers.
State-of-the-art review on atopic eczema, one of the most common skin diseases today. This multi-authored handbook covers all aspects relevant for physicians from various disciplines.
This book focuses on the representation of dermatological diseases in pigmented skin, fills an important gap in the literature, and facilitates better dermatological diagnosis when dealing with patients of various ethnicities. It discusses over 400 diseases and their representations with the help of over 2000 high-quality images and illustrations. This book elaborates on each single disease using easy-to-follow schematics and a focused approach to facilitate reader learning. Pursuing a comprehensive, the book covers not only common skin diseases such as psoriasis, lichen planus, eczema, erythrasma, cutaneous tuberculosis, leprosy, leishmaniasis and oral submucous fibrosis, but also rare tropical diseases such as sporotrichosis, mycetoma, rhinosporodiosis, lobomycosis, mucormycosis and subcutaneous zygomycosis. It also addresses aesthetic concerns by covering hypopigmented and hyperpigmented disorders in pigmented skin such as guttate hypomelanosis, vitiligo, progressive macular hypomelanosis, chemical or physical induced depigmentation, melasma, sebo-melanosis, lichen and macular amyloidosis. Offering comprehensive coverage of dermatological disorders and diseases in pigmented skin, the book is a must-have resource for dermatology trainees and practitioners who treat or care for pigmented skin patients.
A wide-ranging account of the epidemiology of atopic eczema, its prevalence and possible causes.
Atopic dermatitis or atopic eczema is an extremely common skin disease characterized by red patches, dry, scaling or crusting skin, and intense itch. It frequently develops in children during the first year of life and can become severe, with a consequently major impact on health-related quality of life. This text from international experts draws t
Advances in itch research have elucidated differences between itch and pain but have also blurred the distinction between them. There is a long debate about how somatic sensations including touch, pain, itch, and temperature sensitivity are encoded by the nervous system. Research suggests that each sensory modality is processed along a fixed, direct-line communication system from the skin to the brain. Itch: Mechanisms and Treatment presents a timely update on all aspects of itch research and the clinical treatment of itch that accompanies many dermatological conditions including psoriasis, neuropathic itch, cutaneous t-cells lymphomas, and systemic diseases such as kidney and liver disease and cancer. Composed of contributions from distinguished researchers around the world, the book explores topics such as: Neuropathic itch Peripheral neuronal mechanism of itch The role of PAR-2 in neuroimmune communication and itch Mrgprs as itch receptors The role of interleukin-31 and oncostatin M in itch and neuroimmune communication Spinal coding of itch and pain Spinal microcircuits and the regulation of itch Examining new findings on cellular and molecular mechanisms, the book is a compendium of the most current research on itch, its prevalence in society, and the problems associated with treatment.
The prevalence of allergic diseases has increased dramatically over recent decades, both in terms of the number of sufferers and the number of allergies. This is a trend that has frequently been referred to as 'the epidemic of the 21st century'. As described in ancient texts, allergies have been known for over 2,000 years, but the term 'allergy' was only coined at the beginning of the 20th century when doctors began to understand their pathophysiological basis. This book presents a detailed and varied historical overview of the field of allergology. Beginning with insights on allergy from antiquity to the 20th century and the development of the associated terminology, it compiles historical reflections on the understanding of the most common allergic diseases. Important milestones in the discovery of mechanisms of allergy are described, followed by historical accounts of the detection of allergens such as pollen, dust mites, peanuts and latex, and of environmental influences such as pollution and the relationship between farmers and their environment. Several chapters illustrate the progress made in allergy management to date. Particular highlights of this book are the personal reflections of and interviews with a number of pioneers of allergy, including F. Austen, J. Bienenstock, K. Blaser, A. de Weck, A.W. Frankland, K. Ishizaka, and many more. Concluding with portrayals of allergy societies and collections, as well as being supplemented by two films, this book represents a veritable treasure trove of fascinating and richly illustrated information. Not only researchers, physicians and medical historians, but also students and even non-scientists will find History of Allergy a scientific adventure well worth reading.
This book comprehensively reviews the characteristics of the body reflected in the skin due to differences in gender. It investigates the genetic and hormonal differences that can affect skin structure and function, and resulting in variations between women and men. The aging process and exogenous factors that differ according to differences in lifestyle between the sexes are also covered. Gender and Dermatology comprehensively outlines the various aspects of physiological differences between the skin of women and men using practical examples and review of the basic science. It is therefore an important clinically-relevant review for both the trainee and experienced practitioner in dermatology, primary care, geriatrics and immunology, while also being of interest to researchers in genetics and metabolic medicine.
"Many parents today are turning to or seeking information about Complementary and Alternative Medicine (CAM) for their children. Whether you initiate alternative therapies or simply need to respond when asked for information or advice, it's crucial to have the most recent, evidence-based information about alternative therapies and know how to safely and effectively integrate them with conventional treatment. This innovative and reliable reference is the ideal resource to have at hand." "This book includes a wide range of complementary and alternative therapies, focusing on those most often used with children: mind/body approaches, manual therapies, lifestyle approaches, alternative systems, energy medicine, and biological agents. Within these main categories, therapies such as acupuncture, chiropractic, massage, homeopathy, herbs, and magnets are covered." "Fifty-five common pediatric conditions are comprehensively discussed, with diagnostic and evidence-based treatment information, followed by authoritative information on the major CAM therapies available for treatment of the condition. Whenever possible, an integrative approach that combines conventional and alternative approaches is presented."--BOOK JACKET.