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“This is a “must need” for any cytology laboratory performing touch preparations as part of their service or those wanting to offer this to their physicians as an alternative approach to the standard FNA or frozen section... and [it] would be a great addition to your reference library.”---The ASC Bulletin This is the first atlas dedicated to touch preparation cytopathology. Written by established pathologists who are at the cutting edge of this minimally-invasive practice, the Atlas of Touch Preparation Cytopathology presents a comprehensive overview and visual reference guide to the diagnostic applications of touch preparations. This visually-stunning book reviews touch preparations corresponding to all major body systems and includes chapters on specimen handling and processing, intraoperative use during frozen sections, as well as on ancillary testing using touch preps. While most cytopathology atlases have images of smears and fluids, they have very little discussion of touch preparations making this volume a one-of-a-kind resource. The authors, using many picturesque examples in the text, not only include detailed visual and textual discussion of touch preparations but also provide comparative presentations to facilitate correlation with histopathology, FNA smears and ancillary test results. This total coverage illuminates key findings and important considerations of this technique that pathologists can learn from. Written with the practicing pathologist in mind, the Atlas of Touch Preparation Cytopathology is an invaluable book in today‚Äôs pathology practice where there is increasing utilization of small biopsies that can benefit from intraprocedural evaluation and assessment to maximize diagnostic yield. Key Features: Covers various methods of touch preparation and addresses measures to avoid pitfalls. Includes techniques that can serve as helpful tricks during intraprocedural evaluation of small biopsies and at the time of frozen section. Comprehensive coverage of different body systems that are typically sampled with small biopsies and amenable to touch preparations. Contains over 400 touch preparation images and includes corresponding histopathologic figures and ancillary studies.
The aim of this atlas is to guide pathologists and radiologists in the accurate triage and diagnosis of deep seated mass lesions biopsied under ultrasound, CT Scan or fluoroscopic guidance. Fine needle aspiration cytology has become the foremost diagnostic modality in recent years for the diagnosis of mass lesions, including primary and recurrent neoplasms and masses of non-neoplastic and infectious etiology. An essential requirement in the accurate diagnosis of these masses is the correlation of cytomorphology with the radiological findings and adequate triage of acquired material during the biopsy procedure. The cytologic appearance (fine needle aspiration smears, touch preparations, cell blocks and core biopsy), gross surgical resected specimen (where available on follow-up) and imaging findings will be illustrated to provide a complete pathologic-radiologic correlation of the entities discussed. Collection methods and correlation with ancillary studies such as flow cytometry, microbiologic cultures, cytogenetics and immunohistochemistry will be described. The importance of specimen type and cytologic and radiologic techniques will be emphasized.
In the practice of cytopathology, cytologists frequently encounter a spectrum of benign, normal cells in samples. In fact, these normal cells frequently comprise the greatest proportion of material present on a cytology slide. This is frequently the case in Pap smears of the uterine cervix , urine samples, and lung samples such as bronchial brushings. Normal cytology can often mimic pathology leading to misdiagnoses, especially in cases with reactive and metaplastic changes. Moreover, cytopathology findings of certain neoplasms can also mimic normal cytology. Today, cytology laboratories are no longer confined to dealing with just exfoliative specimens and superficial aspirations. With interventional radiology as well as endobronchial and endoscopic ultrasound-guided fine needle aspirations (FNA), we increasingly encounter visceral samples. Hence, cytologists are even likely to encounter normal elements from deep-seated organs. Sometimes, unexpected normal elements may be found within cytology specimens because a FNA procedure has contamination or inadvertently sampled a nearby organ or normal anatomical structure. A typical example is the finding of ganglion cells when a FNA is performed targeting a celiac node for cancer staging (Elgarby EA et al. Frequency and characterization of celiac ganglia diagnosed on fine-needle aspiration. Cytojournal. 2015; 12:4). Despite the importance of knowing the spectrum of normal cytology, there are limited reference materials available on this topic for cytologists. Most cytopathology texts deal with abnormal cytology. Often, the chapters in these books only devote a few sentences about normal cytology (euplasia). Our proposed book intends to fulfil this need. The book will contain a mixture of text and images (atlas). Important aspects related to cytology practice will be highlighted such as clinical relevance, differential diagnoses, mimics and pitfalls. The images will include a variety of cytology specimen preparations (e.g. direct smears, liquid based samples, touch preparations, cell blocks) and stains (e.g. Diff Quik/MGG, Papanicolaou, H&E). In selected cases, the expected immunoprofile of normal cells will be addressed. Each chapter will also include a modest list of helpful and contemporary references.
In the era of precision medicine, physicians are increasingly in need of more definitive diagnostic, prognostic, and predictive information derived from small biopsy specimens such as cytology samples in order to guide effective patient care. Cytopathology is well poised to meet this challenge. Whilst the traditional cytomorphologic component of cytology practice is still valid, enormous advances have been made in the field of cytopathology thanks to transformative technology and innovative individuals that have augmented the cytologists' ability to meet the demands of modern medicine. The purpose of this book is to describe, illustrate, and review many of the most recent developments regarding modern techniques employed in cytopathology. This latest monograph is intended for all cytologists including cytopathologists, cytotechnologists, cytology lab assistants, trainees, research scientists, and anyone who is interested in the field of cytopathology. We have invited pioneering experts in their respective fields to author these chapters. This book is not only the culmination of their groundbreaking work and effort but also presents a critical review of the current literature. We have attempted to provide readers with an informative and comprehensive aid so that they may better appreciate how emerging technology has been applied to cytology. Each chapter in this book presents a stand-alone contemporary review of emerging topics in cytopathology. We hope that you will find this monograph thought-provoking and a valuable reference for your practice.
4 Stars An excellent teaching and reference atlas that presents a comprehensive, integrated approach to diagnostic thyroid cytopathology. Overall, this atlas is an excellent reference with beautiful images and multidisciplinary correlates that provides comprehensive coverage of thyroid malignancies as well as benign, borderline, and non-neoplastic thyroid pathology. The Atlas of Thyroid Cytopathology is a generously illustrated and user-friendly volume that serves as a desk reference and a practical guide in the diagnostically challenging area of thyroid cytopathology. The text is comprised of 500 high-resolution color images that thoroughly illustrate the important aspects of the cytopathology of thyroid disease. Complete coverage of thyroid cytopathology is provided in addition to full coverage of non-neoplastic lesions, benign and borderline neoplasms and papillary thyroid carcinoma, chapters include normal cytology, uncommon primary neoplasms, follicular neoplasms, H?rthle cell neoplasms, medullary thyroid carcinomas, and metastatic and secondary cancers. Selected images of the histopathologic characteristics of the lesions are also included for morphologic correlation, making this text attractive to both cytopathologists and surgical pathologists. Nationally recognized experts in thyroid cytopathology and histopathology provide authoritative analysis of every aspect of thyroid cytopathologic analysis. "
This book provides guidance regarding the approach to common scenarios encountered in the frozen section laboratory while underscoring diagnostic pitfalls and providing the proper level of diagnostic information to ensure clear communication. Given the use of frozen section in molecular and research pathology, the text also serves as a guide for morphologic examination. Written by experts in the field, the book is organized according to organ system with additional chapters discussing the roles of digital pathology and molecular assays. Each chapter is extensively illustrated to highlight key points that facilitate interpretation and highlight areas for potential error. The goal of this book is to help trainees understand the need for mastery of this unique diagnostic tool, and to aid pathologists who cover frozen section convert practical information provided into diagnostic improvements. Frozen Section Pathology is a comprehensive and state-of-the-art review and serves as a valuable resource for the general surgical pathologist with frozen section responsibilities as well as surgeons who regularly utilize frozen section.
Cytology is a unique subspecialty in anatomic pathology, and plays a critical role in the diagnosis of a variety of benign and malignant lesions by using minimally invasive procedures, such as fine needle aspiration, brushing, washing and lavage. Cytology not only provides an accurate diagnosis of the lesion based on the cytomorphological evaluation at cellular level, but also provides material for molecular characterization of a tumor for targeted therapy. In the era of personalized medicine, cytology has continued to grow and evolve as an important diagnostic tool. For example, some types of procedures are routinely used, diagnostic criteria have become more refined, and certain terminology has been changed based on current WHO classifications. Therefore, it is necessary to update our knowledge and terminology in cytology. In this volume, we have retained the quality and the clarity of the series, and like the other volumes, this volume aims to be concise and comprehensive yet clinically relevant to daily practice. Although this volume is written by multiple authors, all chapters follow a similar format: brief introduction of the specific organ/system (including types of specimens and techniques to obtain samples), description of normal findings, and a practice approach to diagnose benign and malignant lesions. In each chapter, the key cytomorphological feature and main differential diagnoses of the lesion are summarized in a concise table. Images in each chapter are instructive and clearly represent findings. Where necessary, we have also illustrated the important ancillary tests, such as flow cytometry, immunohistochemistry and molecular analysis, which are crucial for an accurate diagnosis and targeted therapy. The updated knowledge, including key cytomorphological features, current terminology and molecular diagnostic tests, is the highlight of this volume.
Silverberg's Principles and Practice of Surgical Pathology and Cytopathology is one of the most durable reference texts in pathology. Thoroughly revised and updated, this state-of-the-art new edition encompasses the entire fields of surgical pathology and cytopathology in a single source. Its practice-oriented format uniquely integrates these disciplines to present all the relevant features of a particular lesion, side by side. Over 4000 color images depict clinical features, morphological attributes, histochemical and immunohistochemical findings, and molecular characteristics of all lesions included. This edition features new highly experienced and academically accomplished editors, while chapters are written by the leading experts in the field (several new to this edition, bringing a fresh approach). Dr Steven Silverberg's practical approach to problem solving has been carefully preserved. The print book is packaged with access to a secure, electronic copy of the book, providing quick and easy access to its wealth of text and images.
This book introduces basic ROSE techniques and resources required to set up ROSE service. It reviews the cytomorphologic features that are recognizable during ROSE, including those important for sample adequacy, specimen triage, preliminary interpretation, and potential diagnostic pitfalls. Economic and regulatory aspects are discussed as well as the pros and cons of telecytology. The book is formatted for clinical settings, simulating the ROSE process that occurs in the ultrasound room, CT room, bronchoscopy suite, and endoscopy suite. Each chapter focuses on the cytomorphologic clues and pitfalls of the entities specific to that clinical setting. Rapid On-Site Evaluation: A Practical Guide will be a valuable resource for pathologists, cytotechnologists, physicians who perform biopsies and/or ROSE evaluation, and trainees for utilizing ROSE and improving diagnostic performance of biopsies.
This timeless pocket atlas is the ideal visual companion to histology and cytology textbooks. First published in 1950 and translated into eight languages, Kuehnel's Pocket Atlas of Cytology, Histology and Microscopic Anatomy is a proven classic. The fully revised and updated fourth edition contains 745 full-color illustrations - almost 200 more than were included in the third edition. Superb, high-quality microphotographs and pathologic stains are accompanied by legends, informative texts, and numerous cross-references. Key features of the updated fourth edition: More than 700 high-quality illustrations using advanced techniques in histology and electron microscopy Practical, information Concise and focused text Key concepts and ideas illustrated in less than 550 pages Ideal for exam preparation, this world-class book is an indispensable visual study tool for medical, dental and biology students. It can also serve as an outstanding review and refresher text.