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Written by one of the world's best-known and most active ophthalmic pathologists, this text offers state-of-the-art coverage of the pathology of the eye. Superb, high-quality illustrations focus on key lesions and important diagnostic features. Topics include congenital and developmental anomalies, inflammation, pathology of the retina, uveal melanoma and other intraocular tumors in adults, and much more. Serves as an excellent day-to-day reference or learning tool.
Eye Pathology: An Atlas and Text is a basic introduction to eye pathology that can be read and mastered during an ophthalmic pathology rotation. In addition, it will serve as a well-illustrated resource for residents who are studying for the OKAP examinations or Board certification in ophthalmology. Completely written and illustrated by Dr. Eagle, this single-author text is primarily designed for ophthalmology residents and the comprehensive ophthalmologist not looking for a comprehensive text on the subject.
When a specimen representing a tumour or tumour-like lesion of the eye or ocular adnexa is received in most general surgical pathology laboratories, the immediate reaction is one of panic, because these tumours are rarely encountered and often require complex gross dissections based on a knowledge of ocular anatomy that most general surgical pathologists have either never possessed or have long since forgotten. The authors of this volume state that their main objective is to emphasise the important features of these lesions that are of special interest to general and surgical pathologists. In addition to providing complete descriptions of the tumours and tumour-like lesions in the various compartments of the eye and ocular adnexa, the authors correlate the pathologic features with epidemiologic and pathogenetic observations, clinical features, differential diagnosis, and special studies including immunohistochemistry and various molecular approaches. Each anatomic site has a section on normal anatomy and histology and there is a separate chapter on the pathologic examination of ocular specimens so that the general pathologist can approach these uncommonly-encountered specimens with confidence. Because of its scholarly, practical, well illustrated and well-referenced approach, this work will appeal to pathologists and ophthalmologists alike.
Atlas of Histology of the Juvenile Rat should be of interest to toxicologic pathologists, toxicologists, and other biological scientists who are interested in the histomorphology of juvenile rats. For several decades the laboratory rat has been used extensively in nonclinical toxicology studies designed to detect potential human toxicity of drugs, agrochemicals, industrial chemicals, and environmental hazards. These studies traditionally have involved young adult rats that are 8-10 weeks of age as studies are started. It is becoming increasingly apparent that children and young animals may have different responses to drug/chemical exposures, therefore, regulatory agencies are emphasizing toxicology studies in juvenile animals. While the histologic features of organs from young adult and aged laboratory rats are well known, less is known about the histologic features of organs from juvenile rats. Final histologic maturity of many organs is achieved postnatally, thus immature histologic features must be distinguished from chemical- or drug-related effects. While this postnatal organ development is known to exist as a general concept, detailed information regarding postnatal histologic development is not readily available. The Atlas includes organs that are typically sampled in nonclinical toxicology studies and presents the histologic features at weekly intervals, starting at birth and extending through postnatal day 42. - Written and edited by highly experienced, board-certified toxicologic pathologists - Includes more than 700 high-resolution microscopic images from organs that are typically examined in safety assessment toxicology studies - Detailed figure legends and chapter narratives present the salient features of each organ at each time interval - Figures are available for further study via Elsevier's Virtual Microscope, which allows viewing of microscopic images at higher magnification - Valuable resource for toxicologic pathologists who are confronted with interpretation of lesions in juvenile rats in situations where age-matched concurrent controls are not available for comparison, e.g., with unscheduled decedents - Figures are available for further study on ScienceDirect with Virtual Microscope, which allows viewing of microscopic images at higher magnification
1. Introduction -- 2. Phenotyping -- 3. Necropsy and histology -- 4. Mammary Gland -- 5. Skeletal System -- 6. Nose, sinus, pharynx and larynx -- 7. Oral cavity and teeth -- 8. Salivary glands -- 9. Respiratory -- 10. Cardiovascular -- 11. Upper GI -- 12. Lower GI -- 13. Liver and gallbladder -- 14. Pancreas -- 15. Endocrine System -- 16. Urinary System -- 17. Female Reproductive System -- 18. Male Reproductive System -- 19. Hematopoietic and Lymphoid Tissues -- 20. Nervous System -- 21. Special senses, eye -- 22. Special senses, ear -- 23. Skin and adnexa -- Index.
Now available in an easy-to-use CD-ROM, this state-of-the-art electronic atlas contains more than 1,675 color illustrations from Dr. Yannuzzi's THE RETINA ATLAS. This up-to-date atlas is an ideal diagnostic tool, providing access to a comprehensive library of various medical/retinal disorders and their pathologies with just the click of a mouse. * Features full-color clinical photography, fluorescein angiography, and full-color histopathological pictures supported by black-and-white schematics to create a remarkable collection of illustrations depicting all aspects of the retinal disease process. * Includes Indocyanine Green Angiography (ICG) findings, a technique developed by Drs. Guyer and Yannuzzi for diagnosing and treating retina disease. These images serve as an invaluable resource during the initial patient evaluation and screening process. * Utilizes a powerful search engine which allows the user to locate a specific topic by chapter heading, section, or legend. * Allows the user to simultaneously open multiple windows and images, or configure a split screen to view side-by-side images from two different locations on the disk. * Allows the user to create a personalized "slide show." * Permits personalization with notes, highlighting, and electronic bookmarks, making it easier to locate pertinent information.