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In response to the explosion of research in developmental neurobiology, this new edition of the Atlas of the Developing Rat Brain has been expanded to include all of the plates and diagrams of the previous book, PLUS an additional 95 plates and 95 diagrams delineating the entire rat nervous system. Atlas of the Developing Rat Nervous System features large, high-magnification photographs of serial brain sections of the embryonic and neonatal laboratory rat, with opposing fully labeled diagrams. Complementing the classic atlas by Paxinos and Watson, The Rat Brain in Stereotaxic Coordinates, Second Edition (Academic Press, 1986), this new atlas is the standard reference for developmental neuroscientists. Key Features * Provides section-by-section photographs and accompanying labeled diagrams of the embryonic and neonatal rat brain * Shows brain development at Embryonic Days 14 (Whole embryo), 16, 17, and 19, as well as Postnatal Day 0 * Delineates nerves, ganglia, arteries, veins, bones, and foramina of the head on Embryonic Days 14 and 19 * Depicts 912 brain structures or their primordial counterparts * Large size in an easy-to-use, spiral-bound format * Includes a full list of abbreviations, index of structures, and references * 224 photographs alongside meticulously drawn diagrams depict the central and peripheral nervous system and other body organs * Depicts ages E14, E16, and E19 in the customary coronal and sagittal planes and E17 and P0 in the coronal plane
This text provides a description of the cytoarchitecture, chemoarchitecture, and connectivity of the rat nervous system. In addition it offers updated and supplemented information on the peripheral motor, peripheral somatosensor, vascular, central motor, pain, and additional neurotransmitter systems.
Paxinos and Ashwell's Atlas of the Developing Rat Nervous System, Fourth Edition, builds on the many excellent features of previous editions that have made this book the most cited atlas of the developing rat brain. It provides the most comprehensive depiction of not only the structures in the brain and spinal cord, but also of the peripheral nervous system and target organs that are important for developmental neurobiologists, allowing the user to follow neural structures through the developing embryo in both time and space. The nomenclature and identification of structures in this edition have been thoroughly updated to ensure accuracy and compatibility. - Provides detailed and accurate coverage of the developing rat nervous system from Embryonic Day 11 to Day of Birth - Contains 200 photographs and accompanying diagrams of coronal or sagittal sections of rats aged E11 – E19 - Presents new sections on Histology, Neurogenetics, Imaging, MRI Histology and Panneuronal Markers - Delineates brain structures and peripheral nerves, ganglia, arteries, veins, muscles, bones and other important organs - Serves as an essential tool for researchers in the interpretation of findings resulting from the genetic manipulation of brain development - Includes the Expert Consult eBook version, compatible with PC, Mac, and most mobile devices and eReaders, which allows readers to browse, search, and interact with content
Atlas of Histology of the Juvenile Rat should be of interest to toxicologic pathologists, toxicologists, and other biological scientists who are interested in the histomorphology of juvenile rats. For several decades the laboratory rat has been used extensively in nonclinical toxicology studies designed to detect potential human toxicity of drugs, agrochemicals, industrial chemicals, and environmental hazards. These studies traditionally have involved young adult rats that are 8-10 weeks of age as studies are started. It is becoming increasingly apparent that children and young animals may have different responses to drug/chemical exposures, therefore, regulatory agencies are emphasizing toxicology studies in juvenile animals. While the histologic features of organs from young adult and aged laboratory rats are well known, less is known about the histologic features of organs from juvenile rats. Final histologic maturity of many organs is achieved postnatally, thus immature histologic features must be distinguished from chemical- or drug-related effects. While this postnatal organ development is known to exist as a general concept, detailed information regarding postnatal histologic development is not readily available. The Atlas includes organs that are typically sampled in nonclinical toxicology studies and presents the histologic features at weekly intervals, starting at birth and extending through postnatal day 42. - Written and edited by highly experienced, board-certified toxicologic pathologists - Includes more than 700 high-resolution microscopic images from organs that are typically examined in safety assessment toxicology studies - Detailed figure legends and chapter narratives present the salient features of each organ at each time interval - Figures are available for further study via Elsevier's Virtual Microscope, which allows viewing of microscopic images at higher magnification - Valuable resource for toxicologic pathologists who are confronted with interpretation of lesions in juvenile rats in situations where age-matched concurrent controls are not available for comparison, e.g., with unscheduled decedents - Figures are available for further study on ScienceDirect with Virtual Microscope, which allows viewing of microscopic images at higher magnification
The previous two editions of the Human Nervous System have been the standard reference for the anatomy of the central and peripheral nervous system of the human. The work has attracted nearly 2,000 citations, demonstrating that it has a major influence in the field of neuroscience. The 3e is a complete and updated revision, with new chapters covering genes and anatomy, gene expression studies, and glia cells. The book continues to be an excellent companion to the Atlas of the Human Brain, and a common nomenclature throughout the book is enforced. Physiological data, functional concepts, and correlates to the neuroanatomy of the major model systems (rat and mouse) as well as brain function round out the new edition. - Adopts standard nomenclature following the new scheme by Paxinos, Watson, and Puelles and aligned with the Mai et al. Atlas of the Human Brain (new edition in 2007) - Full color throughout with many new and significantly enhanced illustrations - Provides essential reference information for users in conjunction with brain atlases for the identification of brain structures, the connectivity between different areas, and to evaluate data collected in anatomical, physiological, pharmacological, behavioral, and imaging studies
This atlas provides an accurate and detailed depiction of all brain structures at fetal stage E17.5, Day of birth, and Day 6 postnatal. In addition to brain structures, the atlas delineates peripheral nerves, ganglia, arteries, veins, muscles bones and other organs. It is an indispensable guide for the interpretation of nervous system changes in gene knockout and transgenic mice. Contains: 43 photographs and drawings of Nissl-stained coronal sections of the brain of a fetal mouse at E17.5 days, 65 photographs and drawings of Nissl-stained coronal sections of the brain of a mouse on the day of birth, and 73 photographs and drawings of Nissl-stained coronal sections of the brain of a mouse aged 6 days postnatal. The drawings are based on the study of sections stained with Nissl and a range of neuroactive substances. In addition to brain structures, the atlas delineates peripheral nerves, ganglia, arteries, veins, muscles bones and other organs.
This set can be used for producing and publishing rat brain illustrations.
This book is a companion to the atlas of the adult rat brain (Brain Maps: Structure of the Rat Brain, Elsevier, 1992), using a consistent approach to nomenclature and graphical representation. The two goals of the approach used for the book, are to clarify the basic structural plan of the mammalian brain, and to generate computer graphics maps for summarizing related information, using the rat as a particular model. Included is also a discussion of how similar the development of rat and mouse brains may be, and thus how useful the maps may be as a guide to mouse brain development. The heart of the book is, of course, the atlases of the brain at progressive stages of embryogenesis. Nine representative ages are used, from the simple neural plate stage, to a time just before birth. At each stage, enough levels are presented to illustrate the major known structural features, with additional supporting planes and photomicrographs. The second component of the book discusses the classical approach to interpreting the gross structure of the developing brain, while a third component is more theoretical, and deals with methods to produce flattened maps or footprints of the central nervous system. Finally problems associated with identifying specific structures in the embryonic brain, and the many inconsistencies found in nomenclature associated with the developing and adult rat brain are presented.
Pathology of the Developing Mouse provides, in so far as feasible, one complete reference on the design, analysis, and interpretation of abnormal findings that may be detected in developing mice before and shortly after birth. In particular, this book is designed specifically to be not only a "how to do" manual for developmental pathology expe
This completely revised edition of The Rat Brain in Stereotaxic Coordinates, the second most cited book in science, represents a dramatic update from the previous edition. Based on a single rat brain, this edition features an entirely new coronal set of tissue cut in regular 120 micron intervals with accompanying photographs and drawings of coronal, horizontal and sagittal sections of this new set. The use of the single brain allows for greater consistency between sections, while advances in histochemistry techniques provides increased refinement in the definition of brain areas, making this the most accurate and detailed stereotaxic rat atlas produced to date. The atlas will also include a CD-ROM featuring all of the graphics and text. Every lab working with the rat as an experimental animal model will want to use this book as their atlas of choice.This book is also available in a softcover spiral binding at the same price. - Includes twice as many coronal sections, nissl plates, and sagittal plates as the previous edition - Uses a single rat brain allowing for better consistency and better delineations in the line drawings of structures - Provides improved stereotaxic coordinates at a higher level of detail - Accompanying CD-ROM features graphics and text - Now available as hardcover version and softcover version with a spiral binding at the same price