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First English edition of a rare gem in the neurological sciences A milestone in neuroscience research, this high-profile Atlas depicts the cellular structure of practically every area of the human cortex with direct applications to current research in brain function. The entirety of the 112 original microphotographic plates, brilliant achievements in scientific microphotography and representing the 107 cytoarchitectonic areas of the human cerebral cortex, are reproduced in full size - large enough to be used for teaching purposes. An extensive introduction places the cytoarchitectonic studies of von Economo and Koskinas in a historical as well as a modern perspective, summarizing the essence of their findings and providing Brodmann area correlations. Biographies of von Economo and Koskinas and complete listings of their hard-to-find works are included in the Appendix. Originally published in German in 1925, it was considered a 'royal gift to science'. Revising Brodmann's nomenclature of 1909, the Nobel prize nominee von Economo and his colleague Koskinas took cytoarchitectonics to a new zenith, filling in gaps left by Brodmann on normal cortical structure, and documenting detailed findings in the frontal, parietal, temporal and occipital lobes, the insula, hippocampus, and superior limbic region. Far from being of purely academic or historical interest, this essential guide for all research on the cerebral cortex is of fundamental value to investigators in the brain and behavioral sciences, including basic, cognitive and evolutionary neuroscience, neuroanatomy, neurophysiology, neuroimaging, neuropsychology and neurolinguistics, as well as to physicians in the clinical fields of neurology, neuropathology, neurosurgery and psychiatry.
Originally published in German and French, the work is considered to be unsurpassed in both its scientific eloquence and accurate photographic documentation. Revising Brodmann's cortical parcellation system, von Economo took cytoarchitectonics to a new zenith.>The revised edition contains newly compiled tables with extensive quantitative data on the 107 cytoarchitectonic areas of Economo and Koskinas, plus all the 'transition' areas and full reproductions of the original microphotographs. It also contains the concluding chapter that appeared only in the 1929 English edition, with Economo's later views on cytoarchitectonic neuropathology and evolutionary neuroscience, enriched with material and figures from his later studies. Last but not least a newly discovered manuscript by Georg N. Koskinas, appears in English for the first time. In it, Economo's collaborator presents an insightful analysis of the 'General Part' of their larger textbook of cytoarchitectonics.
This is the third edition of the translation, by Laurence Garey, of "Vergleichende Lokalisationslehre der Grosshirnrinde" by Korbinian Brodmann, originally published by Barth-Verlag in Leipzig in 1909. It is one of the major "classics" of the neurological world. Even today it forms the basis for so-called "localisation" of function in the cerebral cortex. Brodmann's "areas" are still used to designate functional regions in the cortex, the part of the brain that brings the world that surrounds us into consciousness, and which governs our responses to the world. For example, we use "area 4" for the "motor" cortex, with which we control our muscles, "area 17" for "visual" cortex, with which we see, and so on. This nomenclature is used by neurologists and neurosurgeons in the human context, as well as by experimentalists in various animals. Indeed, Brodmann's famous "maps" of the cerebral cortex of humans, monkeys and other mammals must be among the most commonly reproduced figures in neurobiological publishing. The most famous of all is that of the human brain. There can be few textbooks of neurology, neurophysiology or neuroanatomy in which Brodmann is not cited, and his concepts pervade most research publications on systematic neurobiology. In spite of this, few people have ever seen a copy of the 1909 monograph, and even fewer have actually read it! There had never been a complete English translation available until the first edition of the present translation of 1994, and the original book had been almost unavailable for 50 years or more, the few antiquarian copies still around commanding high prices. As Laurence Garey, too, used Brodmann’s findings and maps in his neurobiological work, and had the good fortune to have access to a copy of the book, he decided to read the complete text and soon discovered that this was much more than just a report of laboratory findings of a turn-of-the-twentieth-century neurologist. It was an account of neurobiological thinking at that time, covering aspects of comparative neuroanatomy, neurophysiology and neuropathology, as well as giving a fascinating insight into the complex relationships between European neurologists during the momentous times when the neuron theory was still new.
The number of scientists and laboratories involved with brain mapping is increasing exponentially; and the second edition of this comprehensive reference has also grown much larger than the first (published in 1996), including, for example, five chapters on structural and functional MRI where the fi
Unraveling the functional properties of structural elements in the brain is one of the fundamental goals of neuroscientific research. In the cerebral cortex this is no mean feat, since cortical areas are defined microstructurally in post-mortem brains but functionally in living brains with electrophysiological or neuroimaging techniques – and cortical areas vary in their topographical properties across individual brains. Being able to map both microstructure and function in the same brains noninvasively in vivo would represent a huge leap forward. In recent years, high-field magnetic resonance imaging (MRI) technologies with spatial resolution below 0.5 mm have set the stage for this by detecting structural differences within the human cerebral cortex, beyond the Stria of Gennari. This provides the basis for an in vivo microanatomical brain map, with the enormous potential to make direct correlations between microstructure and function in living human brains. This book starts with Brodmann’s post-mortem map published in the early 20th century, moves on to the almost forgotten microstructural maps of von Economo and Koskinas and the Vogt-Vogt school, sheds some light on more recent approaches that aim at mapping cortical areas noninvasively in living human brains, and culminates with the concept of “in vivo Brodmann mapping” using high-field MRI, which was introduced in the early 21st century.
Growth, as we conceive it, is the study of change in an organism not yet mature. Differential growth creates form: external form through growth rates which vary from one part of the body to another and one tissue to another; and internal form through the series of time-entrained events which build up in each cell the special ized complexity of its particular function. We make no distinction, then, between growth and development, and if we have not included accounts of differentiation it is simply because we had to draw a quite arbitrary line somewhere. It is only rather recently that those involved in pediatrics and child health have come to realize that growth is the basic science peculiar to their art. It is a science which uses and incorporates the traditional disciplines of anatomy, physiology, biophysics, biochemistry, and biology. It is indeed a part of biology, and the study of human growth is a part of the curriculum of the rejuvenated science of Human Biology. What growth is not is a series of charts of height and weight. Growth standards are useful and necessary, and their construction is by no means void of intellectual challenge. They are a basic instrument in pediatric epidemiology. But they do not appear in this book, any more than clinical accounts of growth disorders. This appears to be the first large handbook-in three volumes-devoted to Human Growth.
Broca's region has been in the news ever since scientists realized that particular cognitive functions could be localized to parts of the cerebral cortex. Its discoverer, Paul Broca, was one of the first researchers to argue for a direct connection between a concrete behavior--in this case, the use of language--and a specific cortical region. Today, Broca's region is perhaps the most famous part of the human brain, and for over a century, has persisted as the focus of intense research and numerous debates. The name has even penetrated mainstream culture through popular science and the theater. Broca's region is famous for a good reason: As language is one of the most distinctive human traits, the cognitive mechanisms that support it and the tissues in which these mechanisms are housed are also quite complex, and so have the potential to reveal a lot not only about how words, phrases, sentences, and grammatical rules are instantiated in neural tissue, but also, and more broadly, about how brain function relates to behavior. Paul Broca's discoveries were an important, driving force behind the more general effort to relate complex behavior to particular parts of the cerebral cortex, which, significantly, produced the first brain maps.These early studies also, however, suffered from the use of crude techniques, definitions, and distinctions, as well as from ill founded and misdirected assumptions. Although much has been discovered since Broca's work, even today, these problems have not been completely solved. Nonetheless, particularly as a result of important advances made in neuroimaging during the past two decades, Broca's region and all language areas are currently being investigated from every angle. Indeed, as the volume of research into the relations between brain and language has created several communities, each with its own concepts, methods, and considerations, it seemed that it was time to stop, get together, and reflect on the state of the art.This book is the result of that collective reflection, which took place primarily at the Broca's Region Workshop, held in Julich and Aachen, Germany, in June 2004. In it, Yosef Grodzinsky and Katrin Amunts tried to accomplish a nearly impossible task: to mix intellectual traditions and cultures, and juxtapose rather disparate bodies of knowledge, styles of reasoning, and forms of argumentation. Participants were scientists with diverse backgrounds; each invited to contribute his/her particular take, with the hope that a coherent, perhaps even novel, picture would emerge. All of the participants have a special interest in Broca's Region, and represent the myriad angles from which we currently approach it: neuroanatomy, physiology, evolutionary biology, cognitive psychology, clinical neurology, functional imaging, speech and language research, computational biology, and psycho-, neuro-, and theoretical linguistics. The book's main chapters are the contributions of the Workshop's participants and their research teams. Parts of the discussion during the Workshop are included to underscore the richness of viewpoints, and to give readers an idea of the level of interaction that took place. As Broca's region is such a historically significant concept and rich area, this book contains a collection of classic and recent-yet-classic papers. Along with cutting-edge science, Grodzinsky and Amunts want to remind readers of the celebrated past from which much can be learned. The historical chapters include the first two papers written by Paul Broca, as well some work by two of the most important neurologists of the nineteenth century, Ludwig Lichtheim and John Hughlings-Jackson. Also included are parts of twentieth century papers by Korbinian Brodmann, Roman Jakobson, Norman Geschwind, Harold Goodglass, and Jay Mohr. Because this book both reflects the state of the art in Broca's-region research and contains a tribute to its celebrated past, it will be a valuable resource for student and professional researchers. It will also stimulate further interdisciplinary research, which is a significant contribution, as the project called "Broca's region," encompassing the study of brain/language relations, is far from finished.
A unique review of the essential topographical anatomy of the brain from an MRI perspective, correlating high-quality anatomical plates with high-resolution MRI images. The book includes a historical review of brain mapping and an analysis of the essential reference planes used. It provides a detailed review of the sulcal and the gyral anatomy of the human cortex, guiding readers through an interpretation of the individual brain atlas provided by high-resolution MRI. The relationship between brain structure and function is approached in a topographical fashion with an analysis of the necessary imaging methodology and displayed anatomy. An extensive coronal atlas rounds off the book.
Since Descartes famously proclaimed, "I think, therefore I am," science has often overlooked emotions as the source of a person’s true being. Even modern neuroscience has tended, until recently, to concentrate on the cognitive aspects of brain function, disregarding emotions. This attitude began to change with the publication of Descartes’ Error in 1995. Antonio Damasio—"one of the world’s leading neurologists" (The New York Times)—challenged traditional ideas about the connection between emotions and rationality. In this wondrously engaging book, Damasio takes the reader on a journey of scientific discovery through a series of case studies, demonstrating what many of us have long suspected: emotions are not a luxury, they are essential to rational thinking and to normal social behavior.