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Atherothrombosis refers to the coupling of atherosclerosis and thrombosis, and it is the leading cause of the majority of preventable deaths in the modern world. The medical, economic, social, and societal consequences or atherothrombosis are enormous, which make it a dynamic area for development of new pharmacologic agents. Atherothrombosis in Clinical Practice focuses upon the many clinical manifestations of atherothrombosis and therapies that presently exist, with a focus on evolving therapeutic approaches. First, atherothrombosis is defined and the epidemiology is explored. Then, the specific manifestations of atherothrombosis (coronary artery disease, valvular heart disease, cerebrovascular disease, atrial fibrillation, peripheral artery disease) are concisely covered by distinguished experts in the field. Next, specific medications are discussed, with an emphasis on innovative therapies and investigational agents including experimental lipid-modifying, anti-inflammatory, antiplatelet, and anticoagulant agents. State-of-the-art treatment of hypertension and diabetes is described succinctly. Lifestyle modification, medical therapies, and where appropriate, invasive modalities are discussed. Controversies in areas such as cholesterol management and glycemic control are summarized. Part of the Oxford American Cardiology Library, this handbook provides a practical, evidence-based summary of the condition and the most up-to-date research to equip clinicians in managing this common clinical problem.
Atherothrombosis is a practical, clinically-relevant guide to the many manifestations of atherothrombosis, with an emphasis on evolving therapeutic approaches to the treatment and management of the condition.
Written by the world’s foremost authorities, this volume provides comprehensive coverage of current approaches to the prevention, diagnosis, and management of atherothrombosis and its coronary and noncoronary complications. This edition has been thoroughly updated, sharply focused on clinical information, and trimmed to one manageable volume. Coverage begins with a review of risk factors and prevention, emphasizing lipid abnormalities, hypertension, smoking, diabetes, and obesity. Subsequent sections examine the pathogenesis of atherosclerosis, markers and imaging, acute coronary syndromes, chronic stable angina, and noncoronary atherothrombosis. Clinical presentations, medical management, and the latest interventional strategies are included.
Since publication of the First Edition, advances in the diagnosis and prevention and treatment strategies of the vulnerable plaque have necessitated this greatly expanded second edition. With several new chapters covering mainly diagnostic and treatment options, The Handbook of the Vulnerable Plaque will remain the benchmark text for all interventional cardiologists treating vulnerable patients by providing the physician with comprehensive insight into the world of the vulnerable plaque.
This title will be presented as highly practical information pn pharmaceutical antiplatelet and anticoagulation therapy, written in a quick-access, no-nonsense format. The emphasis will be on a just-the-facts clinical approach, heavy on tabular material, light on dense prose. The involvement of the ISCP will ensure that the best quality contributors will be involved and establish a consistent approach to each topic in the series. Each volume is designed to be between 120 and 250 pages containing practical illustrations and designed to improve understand and practical usage of cardiovascular drugs in specific clinical areas.
Stroke is a major cause of death and the major cause of adult neurological disability in most of the world. Despite its importance on a population basis, research into the genetics of stroke has lagged behind that of many other disorders. However, the situation is now changing. Anincreasing number of single gene disorders causing stroke are being described, and there is growing evidence that polygenic factors are important in the risk of apparently "sporadic" stroke.Stroke Genetics provides an up-to-date review of the area, suitable for clinicians treating stroke patients, and both clinical and non-clinical researchers in the field of cerebrovascular disease. The full range of monogenic stroke disorders causing cerebrovascular disease, including ischaemicstroke, intracerebral haemorrhage, aneurysms and arteriovenous malformations, are covered. For each, clinical features, diagnosis, and genetics are described. Increasing evidence suggest that genetic factors are also important for the much more common multifactorial stroke; this evidence isreviewed along with the results of genetic studies in this area. Optimal and novel strategies for investigating multifactorial stroke, including the use of intermediate phenotypes such as intima-media thickness and MRI detected small vessel disease are reviewed. The book concludes by describing apractical approach to investigating patients with stroke for underlying genetic disorders. Also included is a list of useful websites.
Atherosclerosis is a subject of enormous contention for cardiologists and in general for all medical doctors. With this publication we have given you a concise "state-of-the-art" look at the world of atheroma. Many other elements could be included and so it is only a brief analysis of "today" (the preventive medicine era) and "tomorrow" (transforming the cure medicine era into the care medicine era) but also remembering "yesterday" (the ex-cathedra medicine era). Let's hope our arteries are free from atherosclerotic events: have a good read!
This book reviews current science and applications in fields including thrombosis and hemostasis, signal transduction, and non-thrombotic conditions such as inflammation, allergy and tumor metastasis. It is a detailed, up-to-date, highly referenced text for clinical scientists and physicians, including recent developments in this rapidly expanding field. More than a scientific resource, this is also an authoritative reference and guide to the diagnosis.
Expert guidance from internationally recognized authorities, who provide clear and current updates on all aspects of interventional cardiology. This new edition; Contains a radically expanded chapter contents list presented in four clear sections; coronary interventions, interventional pharmacology, structural heart interventions, and endovascular therapy Includes 46 new chapters, including the latest advances in bioresorbable coronary stents, advanced transcatheter aortic valve replacement, MitraClip, new transcatheter mitral valve interventions, and more Chapters are templated for rapid referral, beginning with pathophysiological background and relevant pathology, moving to mechanisms of treatment, device description, procedural techniques, follow-up care, and ending with risks, contraindications and complications Multiple choice questions at the end of each chapter for self-assessment, a total of more than 400 MCQs in the book Features 19 procedural videos, hosted on a companion website
The authoritative clinical handbook promoting excellence and best practice Cardiovascular Prevention and Rehabilitation in Practice is a comprehensive, practitioner-focused clinical handbook which provides internationally applicable evidence-based standards of good practice. Edited and written by a multidisciplinary team of experts from the British Association for Cardiovascular Prevention and Rehabilitation (BACPR), this book is invaluable for practitioners helping people with heart disease return to health. The text provides an overview of research findings, examines the core components of cardiac rehabilitation, and discusses how to support healthier lifestyles and reduce the risks of recurrence. Now in its second edition, this textbook has been fully revised to incorporate recent clinical evidence and align with current national and international guidelines. Increased emphasis is placed on an integrated approach to cardiac rehabilitation programmes, whilst six specified standards and six core components are presented to promote sustainable health outcomes. Describes how cardiovascular prevention and rehabilitation programmes can be delivered to meet standards of good practice Covers a broad range of topics including: promoting health behaviour change to improve lifestyle risk factors, supporting psycho-social health, managing medical risk factors, and how to develop long-term health strategies Emphasises the importance of early programme commencement with assessment and reassessment of patient goals and outcomes, and gives examples of strategies to achieve these Discusses the role of programme audit and certification of meeting minimum standards of practice Looks to the future and how delivery of cardiovascular prevention and rehabilitation programmes internationally will need to meet common challenges Cardiovascular Prevention and Rehabilitation in Practice is an indispensable resource for all health professionals involved in cardiac rehabilitation and cardiovascular disease prevention.