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The 1969 Proceedings of the Plenary Session of the European Organization for Research on Treatment of Cancer have been divided between two volumes of a com pletely different nature. Volume 29, Aseptic Environments and Cancer Treatment, deals not only with the treatment of all types of cancer but also with aplastic treatment of bone marrow and certain other pathological conditions, such as immunological insufficiency, bums etc. Hence the volume will be of interest not only to carcinologists and haematologists but also to paediatricians, surgical units, intensive-care units, hospital administrators and architects and engineers who specialize in hospital design and equipment. Volume 30, Advances in the Treatment of Acute (Blastic) Leukemias, deals with a particular form of cancer and will have a more restricted readership of carcinologists specializing in leukemia and all haematologists. Paris, April 1970 GEORGES MATHE Contents Introduction. G. MATHE. 1 Five Years Experience of the Clinical Use of a Pathogen-Free Isolation Unit. G. MATHE, M. SCHNEIDER, 1. SCHWARZENBERG, J. 1. AMIEL, A. CATTAN, J. R. SCHLUMBERGER, M. HAYAT, F. DE VASSAL, CL. JASMIN, and CL. ROSEN- FELD. With 3 Figures . 3 Protected Environments and the Use of Antibiotics. H. E. M. KAY, J. BYRNE, B. JAMESON, and J. LYNCH . 14 Protected Environment, Prophylactic Antibiotics and Cancer Chemotherapy.
Image-Guided Cancer Therapy: A Multidisciplinary Approach provides clinicians with in-depth coverage of the growing, dynamic field of interventional oncology. Combining the knowledge of expert editors and authors into one powerhouse reference, this book looks at tumor ablation, HIFU, embolic therapies, emerging technologies, and radiation therapy throughout the body (liver, bone, breast, gynecologic and prostate cancers, to name just a few) , and includes discussion of different imaging modalities. In the words of Peter Mueller, MD, author of the book’s Foreword: “... The senior authors are all world renowned experts in interventional oncology, which is another example of the high quality authorship and experience that is brought to this book. The later chapters discuss therapies that are simply not covered in any other source. Everyone who is doing or wants to do ablation therapies and interventional oncology will face a time when they will be asked to use their expertise in less used and less investigated areas. There is nowhere else where the reader can get information on the prostate, breast, and gynecologic areas, and especially pediatrics....This book is an outstanding contribution to the literature and will become a ‘must read’ for all physicians who are interested in Interventional Oncology.”
The culture of cancer cells is routinely practiced in many academic research centers, biotechnology companies, and hospital laboratories. Cancer Cell Culture: Methods and Protocols describes easy-to-follow methods to guide both novice and more experienced researchers seeking to use new techniques in their laboratories. Our present understanding of the cell and molecular biology of cancer has been derived mainly from the use of cultured cancer cells and we cover a number of the most widely used assays to study function in current use. Part I introduces the basic concept of cancer cell culture and this is followed by a description of the general techniques used in many cell culture facilities. The importance of cell line characterization is now widely recognized and methods to characterize and authenticate cell lines are described in Part II. Part III covers the isolation and development of specific cancer cell types and provides valuable tips for those wishing to derive new cell line models. A wide range of procedures encompassing many of the key functional features of cancer cells are described in Part IV including assays to evaluate clonogenicity, cell proliferation, apoptosis, adhesion, migration, invasion, senescence, angiogenesis, and cell cycle parameters. Methods to modify cancer cells are described in Part V, including protocols for transfection, development of drug-resistance, immortalization, and transfer in vivo. In Part VI methods of coculture of different cell types and contamination of cell lines are covered.
This is a well conceived and executed volume detailing in close to encyclopedic proportions the question of control of air borne contamination in hospital environments. Many different ap plication areas are described and well documented. Alternative solutions are presented in historical perspective with the neces sary scientific background to provide the uninitiated an oppor tunity to learn not only how to solve a particular problem but more critically why one solution is preferable to another. Every clinician concerned for his patients' welfare must consider the quality of the environment within the hospital--for only there is it potentially controllable Airborne dissemination of nosocomial infections are considered generally rare today. This may be the result of improved intrahospital environmental control or better infection control techniques. If one considers airborne contaminatiqn, real or potential, as undesirable within certain areas of a hospital then proper environmental control must be included in the framework of the physical and functional struc ture. Often it is difficult to specify which controls are needed for a specific application. Frequently this is a problem of in adequate knowledge of the application area and not the availability of technology. Too often, in the rush to provide a solution the newest and most sophisticated equipment is chosen, installed, and found to be more than is required for the task. To avoid these types of errors it is necessary to provide a series of alternative solutions for each problem.
First multi-year cumulation covers six years: 1965-70.
Quality Assurance of Aseptic Preparation Services Standards Handbook (also known as the Yellow Guide) provides standards for unlicensed aseptic preparation in the UK, as well as practical information to aid implementation of the standards. The handbook delivers essential standards in a practical way and in a format that will be useful for pharmacy management, staff working in aseptic preparation units and those whose role it is to audit the services. The accompanying support resources help with understanding the complexities of relevant topics including microbiology, radiopharmaceuticals, advanced therapy medicinal products, technical (quality) agreements and capacity planning. All the standards have been revised and updated for this 5th edition. The text is produced on behalf of the Royal Pharmaceutical Society (RPS) and the NHS Pharmaceutical Quality Assurance Committee. New in this edition: Replaces the 4th edition standards and forms the basis for an ongoing audit program in the NHS Many new and revised standards Greater emphasis on Pharmaceutical Quality Systems; the responsibilities of pharmacy management, Chief Pharmacists (or equivalent), has been expanded in line with developments in Good Manufacturing Practice Reformatted into 2 parts: standards and support resources. This is a new collaboration between the RPS and NHS. Since the previous edition the RPS has become the professional body for pharmacists and pharmaceutical scientists. RPS launched these standards as part of a library of professional standards and a programme of work to create standards for all areas of pharmacy. The Handbook is essential for pharmacists, hospital pharmacy management and technical services teams, and auditors of unlicensed NHS hospital pharmacy aseptic preparation services in the UK, pharmacists and regulators. The text is used to inform standards used in several other countries.
The Pros and Cons of Cancer Registration E. Grundmann It may seem strange for somebody to hold a symposium on cancer regis tration and then submit a paper under the heading "The Pros and Cons of Cancer Registration." Indeed, this may be quite amazing to those of my colleagues who have been endeavoring for years or decades to provide a world-wide system of cancer registration. To be quite frank, this is exactly what I intended. Generally speaking, as scientists we are convinced that the work we do is worth while. We are in fact supported in this attitude by pub lic opinion, if one bears in mind that science is future-oriented. It may be said that science is a way for building the future, and that progressive-mindedness is - to use a modern word - "in." Never theless, we may somehow hesitate at this fashionable word. After all, science is not "in" in the way this word is interpreted by the younger generation. Indeed, this younger generation is much too sceptical whenever confronted with anything done by the older generation - and science is pursued primarily by the "establishment." Rather, it is "in" to criticize the system of society and, if possible, to overcome this system, which is responsible not only for many evils, but also for many illnesses.
Recent Results in Cancer Research: Current Problems in the Epidemiology of Cancer and Lymphomas is a collection of papers that tackles the various areas of concerns in cancer research. The text covers the general problems, such as the histopathological definition and classification of tumors. The book also deals with the various types of cancer, such as breast, liver, and prostrate cancers. The selection will be of great use for medical researchers and practitioners, particularly those who are involved in treating and studying cancers.