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This book breaks with three common scholarly barriers of periodization, discipline and geography in its exploration of the related themes of heresy, magic and witchcraft. It sets aside constructed chronological boundaries, and in doing so aims to achieve a clearer picture of what ‘went before’, as well as what ‘came after’. Thus the volume demonstrates continuity as well as change in the concepts and understandings of magic, heresy and witchcraft. In addition, the geographical pattern of similarities and diversities suggests a comparative approach, transcending confessional as well as national borders. Throughout the medieval and early modern period, the orthodoxy of the Christian Church was continuously contested. The challenge of heterodoxy, especially as expressed in various kinds of heresy, magic and witchcraft, was constantly present during the period 1200-1650. Neither contesters nor followers of orthodoxy were homogeneous groups or fractions. They themselves and their ideas changed from one century to the next, from region to region, even from city to city, but within a common framework of interpretation. This collection of essays focuses on this complex.
Anagram Solver is the essential guide to cracking all types of quiz and crossword featuring anagrams. Containing over 200,000 words and phrases, Anagram Solver includes plural noun forms, palindromes, idioms, first names and all parts of speech. Anagrams are grouped by the number of letters they contain with the letters set out in alphabetical order so that once the letters of an anagram are arranged alphabetically, finding the solution is as easy as locating the word in a dictionary.
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Alphaherpesviruses are a fascinating group of DNA viruses that includes important human pathogens such as herpes simplex virus type 1 (HSV-1), HSV-2, and varicella-zoster virus (VZV): the causative agents of cold sores, genital ulcerous disease, and chickenpox/shingles, respectively. A key attribute of these viruses is their ability to establish lifelong latent infection in the peripheral nervous system of the host. Such persistence requires subversion of the host's immune system and intrinsic antiviral defense mechanisms. Understanding the mechanisms of the immune evasion and what triggers viral reactivation is a major challenge for today's researchers. This has prompted enormous research efforts into understanding the molecular and cellular biology of these viruses. This up-to-date and comprehensive volume aims to distill the most important research in this area providing a timely overview of the field. Topics covered include: transcriptional regulation, DNA replication, translational control, virus entry and capsid assembly, the role of microRNAs in infection and oncolytic vectors for cancer therapy. In addition there is coverage of virus-host interactions, including apoptosis, subversion of host protein quality control and DNA damage response pathways, autophagy, establishment and reactivation from latency, interferon responses, immunity and vaccine development. Essential reading for everyone working with alphaherpesviruses and of interest to all virologists working on latent infections.
An easy-to-use dictionary of over 80,000 rhyming words.