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This book provides the latest information on fish lectins from the perspective of inflammation and presents new ideas on the complicated mechanisms of lectin biochemistry and associated interactions. Key features include discussion of mechanisms recently identified to be involving lectin family types, presentation of the latest evidence regarding the molecular approaches in fish lectins, and thorough explanation of the concept of antimicrobial and immunological roles and current understanding of the significance of its disease resistance related studies. Gene expression studies is another important element of the book, and it is proposed that gene editing technology provides gaining attention in the biological role of fish lectin research. Examples of the many lastest molecular approaches, applications and future perspectives in fish lectin specific topics covered in this book include the information right from the basics to the advancements in this area. The book will be a valuable update and resource for both experienced and younger researchers working in the field of lectins and immunology.
Glycans (carbohydrate chains) of marine creatures are rich and diverse in polysaccharides, glycoproteins, and glycolipids. The chains that are metabolized by glycan-related enzymes (glycosyltransferases and glycosidases) are recognized by glycan-binding proteins (lectins) which regulate cellular processes such as growth, differentiation, and death. Marine glycomics that involves the genome and transcriptome accelerates our understanding of the evolution of glycans, glycan-related enzymes, and lectins. From 2017 to 2019, the Special Issue “Marine Glycobiology, Glycomics and Lectins” of the journal Marine Drugs published scientific articles and reviews, on the background of “glycobiology”—that is, glycan-based biosciences. The aim was to promote the discovery of novel biomolecules that contribute to drug development and clinical studies. This has great potential for establishing connections between the fields of both human health and marine life sciences. This book contains 11 scientific papers representing current topics in comprehensive glycosciences related to therapeutic agents from marine natural products, as outlined.
The books described marine glycoconjugates. Two articles concern microalgal metabolites such as steroid and sphingoid glycoconjugates, and a glycoprotein from a sea cucumber with interesting biological activities, respectively. One article discusses the fatty acid composition and thermotropic behavior of glycolipids and other membrane lipids of green macrophyte Ulva lactuca. Three articles cover lectin subjects. One review article analyzes perspectives of marine and freshwater lectins’ application in experimental oncology and the therapy of oncological diseases; another article describes the use of a sponge lectin in the construction of a recombinant virus. The third article concerns the function of the immunity of a lectin in producing this compound crinoid. Two articles concern steroid glycosides from starfish, and two others concern triterpene glycosides from sea cucumbers. One article describes the effect of a glycosaminoglycan from the sea cucumber Apostichopus japonicus on hyperglycemia in the liver of insulin-resistant mice. One article concerns the isolation of 10 new triterpene glycosides from a fungus associated with a sea cucumber. The article by Dworaczek et al. characterizes the O-specific polysaccharide (O-antigen) of a bacterial pathogen of common carp by chemical and immunochemical methods. In total, the Special Issue comprises14 articles, including the editorial and two reviews.
Food proteins and bioactive peptides play a vital role in thegrowth and development of the body’s structural integrity andregulation, as well as having a variety of other functionalproperties. Land animal-derived food proteins such as collagen andgelatine carry risks of contamination (such as BSE). Marine-derivedproteins, which can provide equivalents to collagen and gelatinwithout the associated risks, are becoming more popular amongconsumers because of their numerous health beneficial effects. Mostmarine-derived bioactive peptides are currently underutilized.While fish and shellfish are perhaps the most obvious sources ofsuch proteins and peptides, there is also the potential for furtherdevelopment of proteins and peptides from sources like algae, seacucumber and molluscs. Marine-derived proteins and peptides alsohave potential uses in novel products, with the possibility of widecommercialization in the food, beverage, pharmaceutical andcosmetic industries, as well as in other fields such asphotography, textiles, leather, electronics, medicine andbiotechnology. Marine Proteins and Peptides: Biological Activities andApplications presents an overview of the current status,future industrial perspectives and commercial trends of bioactivemarine-derived proteins and peptides. Many of the industrialperspectives are drawn from the food industry, but the book alsorefers to the pharmaceutical and cosmetics industries. There haverecently been significant advances in isolating functionalingredients from marine bio-resources and seafood by-products foruse in these industries, but little has been published, creating aknowledge gap, particularly with regard to the isolation andpurification processes. This book is the first to fill thatgap. Marine Proteins and Peptides: Biological Activities andApplications is a valuable resource for researchers inmarine biochemistry field as well as food industry managersinterested in exploring novel techniques and knowledge onalternative food protein sources. It will become a standardreference book for researchers involved in developing marinebio-resources and seafood by-products for novel nutraceutical,cosmetics, and pharmaceutical applications. It will also appeal tomanagers and product developers in the food, pharmaceutical andcosmetics industries, particularly those looking to usemarine-derived proteins and peptides as substitutes or replacementsfor unfashionable or outdated food components.
E. L. Cooper In Volume 23 we considered, in seven chapters, the basic armamentarium of the invertebrate immune system and its cells, as well as an analysis of antigens, setting the stage for the initiation of an immune response. We studied cell products, natural or induced, as revealed by nonspecific and specific responses following antigenic challenge such as the pro phenol oxidase system, the lytic responses, the Ig superfamily, and the place this family offers invertebrates and insect hemolymph proteins as candidates for membership. At this point, these various topics seemed to converge, almost to overlap, in some instances, presenting a challenge as to how to move from one subject to another. Chapter 1, in this volume offers the bridge to Volume 23 and its final Chapter 7. This Volume 24 contains contributions pertaining to cell activities and the environment. Chapters 1-4 refer specifically to interactions between cells and the integration of cell activities. The focus is on a functional immune system, with antigenic challenge as a subtopic. In Chapters 5-7, the environment is considered from several points of view and the main subtopic here is the result of the consequences of connections and missed signals. The internal and external environments are treated, revealing what may happen when normal immune responses are interfered with. All this is integrated by the consideration of the three great regulatory systems, the ever-present network that somehow acts as the monitor or control for all incoming and outgoing signals.
This book provides a comprehensive examination of the role of Bacillus bacteria in aquaculture, particularly focusing on finfish and shellfish. It begins with foundational chapters on the anatomy and physiology of these aquatic species, their immune systems, and the biology of Bacillus bacteria. The book discusses the specific interactions between Bacillus and the gastrointestinal tracts of fish and shellfish, examining the production and effects of Bacillus-derived exoenzymes and bacteriocins and their role in enhancing aquatic animal health and water quality. Additionally, the book covers the role of Bacillus in bioremediation, particularly in improving water quality, which is a significant concern in aquaculture. The latter sections delve into the application of Bacillus as probiotics and paraprobiotics in fish and shellfish culture, their integration in feed biotechnology, and a critical evaluation of their safety. The book concludes with a critical discussion on the safety and regulatory aspects of using Bacillus in aquaculture. This book is intended for professionals and practitioners in the aquaculture industry and researchers, academicians, and students in the fields of microbiology, marine biology, aquaculture, and veterinary medicine.
This book is about relevant recent research topics in understanding aquaculture for practical approaches; aquatic science, engineering, feed and nutrition, immunology and health are reviewed. The book includes information on why certain fish strains differ in disease resistance, all the current data on fish cell populations, the regulation of the response by factors, and the major histocompatibility complex are explained in detail. The book contains the chapters on nutrition, feed and feed additives, ecology, immunology, microbiology, toxicology, biochemistry, nanotechnology, pharmacology, and biotechnology, among other fields of basic and applied research. Over the past era, scientists have recognized the importance of nutrition in maintaining the health of humans and other animal species, including fish. Humans and other terrestrial animals were the focus of previous research on the links between nutrition, immune response, and disease resistance. However, attempts to conduct similar studies using fish have met with limited success in the last two decades due to a lack of understanding of the immune response in fish. In most facilities, the animals are kept at relatively high densities, causing stress and disease problems are the challenges that we face today and this book opens up the exciting new area of research to truly understand the relationship between fish genetics and immune reactivity. The aquatic immune system turns out to be a crucial reference as aquatic products are increasingly used as model systems for vertebrate immune systems. This book provides that the research students and scientists with a useful text on the latest knowledge of the aquatic feed and nutrition, immune system, cutting-edge technologies, draws everyone’s attention to the practice of small-scale aquaculture and provides a guide on how to responsibly use the water ecosystem and the steps needed to develop, test and market fish vaccines. The chapters will serve as introductions to these fields and up-to-date reviews of recent research advances. This book is intended for a wide range of readers, including nutritionists, disease specialists, feed formulators, students, extension specialists, and farmers, as well as university teachers, graduates and doctoral students in zoology, physiology, aquaculture, and biology in general.
Nutrition and diet play a crucial role in sustaining good health throughout human lives. Food provides us with essential nutrients involved in many physiological activities and biological processes in the body including growth and development, metabolism, immune function, and overall well-being. Nutrition and Diet in Health: Principles and Applications reviews and discusses the issues related to the roles of nutrition and diet in human health and diseases. The book contains two sections – one section features principles, the other, covers applications. Part I provides information on sustainable use of nutrition and diets in health and diseases; advanced biotechnological approaches to improve nutritional content of food; trace elements in nutrition; drug and nutrient interactions; functional foods and nutraceuticals in health maintenance; and biomarkers of functional foods and nutraceuticals in health maintenance. Part II discusses the significance of nutrition in selected human diseases, including cardiovascular diseases, cancer, infection, neurodegenerative diseases, and metabolic co-morbidities. It also discusses optimal nutrition for wellness, fitness, pregnancy, mental health, aging, and longevity. Features Molecular and cellular-based research findings on the principles and applications of nutrition and diet in health Roles of nutritional agents in the pathogenesis of human diseases Underlying mechanisms that govern activities and strategies to prevent pathological conditions using nutritional agents Nutrition and Diet in Health: Principles and Applications is suitable for academia and scientists, enhances knowledge of students in healthcare and areas of biological sciences.