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Contents: Keynote PapersBiomechanicsConstitutive ModellingFracture, Fatigue and DamageGeo-Mechanics and MiningImpact and DynamicsMeasurement and Case StudiesMachining and SurfacingMetal FormingParticle MaterialsSmart Structures, Structure Repair and MonitoringStress, Deformation and CompositesStructural Mechanics and OptimisationTribology, Manufacturing and MachineryVibration and Time-Dependent Deformation Readership: Graduate students, academics, researchers and practitioners in engineering mechanics, aerospace engineering and materials engineering. Keywords:
This book deals with a group of architectured materials. These are hybrid materials in which the constituents (even strongly dissimilar ones) are combined in a given topology and geometry to provide otherwise conflicting properties. The hybridization presented in the book occurs at various levels - from the molecular to the macroscopic (say, sub-centimeter) ones. This monograph represents a collection of programmatic chapters, defining archimats and summarizing the results obtained by using the geometry-inspired materials design. The area of architectured or geometry-inspired materials has reached a certain level of maturity and visibility for a comprehensive presentation in book form. It is written by a group of authors who are active researchers working on various aspects of architectured materials. Through its 14 chapters, the book provides definitions and descriptions of the archetypes of architectured materials and addresses the various techniques in which they can be designed, optimized, and manufactured. It covers a broad realm of archimats, from the ones occurring in nature to those that have been engineered, and discusses a range of their possible applications. The book provides inspiring and scientifically profound, yet entertaining, reading for the materials science community and beyond.
A guide to the important chemical engineering concepts for the development of new drugs, revised second edition The revised and updated second edition of Chemical Engineering in the Pharmaceutical Industry offers a guide to the experimental and computational methods related to drug product design and development. The second edition has been greatly expanded and covers a range of topics related to formulation design and process development of drug products. The authors review basic analytics for quantitation of drug product quality attributes, such as potency, purity, content uniformity, and dissolution, that are addressed with consideration of the applied statistics, process analytical technology, and process control. The 2nd Edition is divided into two separate books: 1) Active Pharmaceutical Ingredients (API’s) and 2) Drug Product Design, Development and Modeling. The contributors explore technology transfer and scale-up of batch processes that are exemplified experimentally and computationally. Written for engineers working in the field, the book examines in-silico process modeling tools that streamline experimental screening approaches. In addition, the authors discuss the emerging field of continuous drug product manufacturing. This revised second edition: Contains 21 new or revised chapters, including chapters on quality by design, computational approaches for drug product modeling, process design with PAT and process control, engineering challenges and solutions Covers chemistry and engineering activities related to dosage form design, and process development, and scale-up Offers analytical methods and applied statistics that highlight drug product quality attributes as design features Presents updated and new example calculations and associated solutions Includes contributions from leading experts in the field Written for pharmaceutical engineers, chemical engineers, undergraduate and graduation students, and professionals in the field of pharmaceutical sciences and manufacturing, Chemical Engineering in the Pharmaceutical Industry, Second Edition contains information designed to be of use from the engineer's perspective and spans information from solid to semi-solid to lyophilized drug products.
IC-SEC 2002 serves as a forum for engineers and scientists who are involved in the use of high performance computers, advanced numerical strategies, computational methods and simulation in various scientific and engineering disciplines. The conference creates a platform for presenting and discussing the latest trends and findings about the state of the art in their particular field(s) of interest. IC-SEC also provides a forum for the interdisciplinary blending of computational efforts in various diversified areas of science, such as biology, chemistry, physics and materials science, as well as all branches of engineering. The proceedings cover a broad range of topics and an application area which involves modelling and simulation work using high performance computers.
Selected, peer reviewed papers from the Second International Conference on Smart Diagnostics of Structures, November 14-16, 2011, Cracow, Poland