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This book presents the latest evidence and guidelines supporting the use of anticoagulant therapy for various clinical scenarios. The field of anticoagulation therapy is evolving rapidly, particularly since the arrival and widespread adoption of direct oral anticoagulants. Organized in two parts, this book reviews the pharmacologic properties of various anticoagulants and details the clinical applications of anticoagulant therapy. Drugs such as warfarin and unfractionated heparin, as well as parenteral and direct oral anticoagulants are discussed in terms of their pharmacokinetics, drug-disease interactions, dosing strategies, and risk considerations. Clinical applications of anticoagulant therapy in disorders such as acute coronary syndromes, atrial fibrillation, and thrombophilia and in special populations such as pregnant women, the elderly, and in the patient with cancer are highlighted. Clinical vignettes, algorithms, clinical pearls, and self-assessment questions are integrated throughout the book. Featuring contributions from authorities in the field, Anticoagulation Therapy is an essential resource for cardiologists, vascular medicine specialists, hematologists, internists, and all other healthcare professionals who prescribe anticoagulants.
Although highly effective in preventing thromboembolic events, the safe management of anticoagulant therapy continues to be a major challenge, requiring constant monitoring and coordinated models of patient-centered care. Anticoagulation Therapy: A Clinical Practice Guide, Second Edition, helps take the guesswork out of managing these therapies and provides essential recommendations. This revised and expanded edition includes: Extensive new information on the direct oral anticoagulants (DOACs) Expanded information on anticoagulant reversal and expanded use of prothrombin complex concentrates New chapters on the use of anticoagulants in special patient populations, the use of anticoagulants in patients with mechanical devices, anticoagulation care delivery standards, regulatory issues, and more Four new appendices on the effect of DOACs on chemotherapy, nutritional influences, types of central nervous system hemorrhage, and use of anticoagulation in patients with coagulopathies
Showcasing the expertise of top-tier specialists who contributed to the newly released guidelines for the care of thrombosis in cancer patients, this exciting guide was written and edited by members of the American Society of Clinical Oncology panel, (ASCO), on the prevention and treatment of cancer-associated thrombosis, among others, and provides
The anti-coagulant Coumadin� can be challenging to manage -- slight changes in its blood levels can lead to either ineffectiveness and stroke or bleeding episodes. What's more, a wide range of foods and medications can alter blood levels in conjunction with this medication. In a single, accessible book, author Diana Schneider explains how Coumadin� works, letting readers understand how food and medications alter its effects. She also provides information on how to enjoy a normal, healthy diet while using the drug, manage unusual situations, travel with Coumadin�, and much more.
This book provides a practical guide to the use of novel and conventional anticoagulants for a variety of medical conditions and patients profiled. It reviews data for selecting the most appropriate medication for a given presentation based on a patient’s background while highlighting current best practices. Chapters discuss the choice of agents and optimum duration of therapy while including the relevant literature review and evidence. Specific sections focus on the use of anticoagulants in patients with cardiovascular disease, autoimmune and rheumatologic disorders, antiphospholipid syndrome, cancer, and in the surgical contexts. The book also examines anticoagulation in pregnant and lactating women, pediatric and elderly populations, and patients with extreme weights. Intended for use in daily practice, Precision Anticoagulation Medicine - A Practical Guide is an essential resource for physicians and related professionals, residents, fellows, and graduate students in hematology, cardiology, rheumatology, oncology, surgery, anesthesiology, and intensive care.
Anticoagulants can be dangerous drugs. Developed to save lives by preventing and treating thrombosis, these widely used medications are linked to unacceptable levels of morbidity and mortality. According to a study by the Institute for Safe Medication Practices, 8.2% of hospitalized patients on warfarin and 13.6% exposed to heparin experience an adverse drug event. To prevent these events from occurring, clinicians monitor anticoagulation therapy closely. But there are still questions. What is the risk of stroke in a patient who has specified CHADS2 risk factors? What is the recommended perioperative treatment? Find life-saving solutions quickly to these challenges and more with Anticoagulation Therapy: A Point-of-Care Guide, edited by William Dager, Michael Gulseth, and Edith Nutescu. This concise reference is designed with the busy clinician and resident in mind. It provides a quick way to access necessary clinical and therapeutic information that has the potential to improve the lives when many risk factors are at play and time is of the essence. Inside you’ll find: Quick reference elements such as tables figures to easily access key information Clinical pearls and bullets to highlight real life application Selected guideline statements from leading organizations 19 chapters covering a broad range of topics The second book in the Point-of-Care series, Anticoagulation Therapy is led by a team of editors with more than 77 combined years of clinical experience, including insight from 19 contributors. The book is divided into three sections, including: Anticoagulation Medication Management, Conditions Requiring Anticoagulation Therapy, and Practical Monitoring and Coagulation Laboratory Insights.
The value of echocardiography in the diagnostic work-up of patients with suspected acute pulmonary embolism.- New developments in the thrombolytic therapy of venous thrombosis.- Mechanism of blood coagulation. Newer aspects of anticoagulant and antithrombotic therapy.MR-angiography in the diagnosis of pulmonary embolism.Scintigraphy-ventilation/perfusion scanning and imaging of the embolus.- Clinical course and prognosis of acute pulmonary embolism.- The molecular mechanisms of inherited thombophilia.
This supplemented manual provides health care professionals with a comprehensive and continuously current reference source pertaining to the management of patients receiving anticoagulants. It provides a hands-on tool for establishing anticoagulation clinics as well as an excellent resource for already established clinics. This manual is a valuable resource for health care providers managing patients on anticoagulation therapy outside the clinic setting. It contains a wide range of educational materials including: standard text, algorithms, critical pathways, case studies, sample forms, policies and procedures in current use, and teaching aids for patients. It addresses issues of manpower needs for clinic development, reimbursement methodologies, and has a section on legal ramifications of oral anticoagulation therapy. It also addresses the role of anticoagulation clinics in the era of managed care.
The available parenteral and oral anticoagulants have a large clinical use. Understanding biochemistry of anticoagulants may help to improve therapeutic strategies. Resistance to vitamin K antagonist drugs might be a problem for rodent populations. Patients who have thrombogenic risk factors should be anticoagulated. The need for cardiac implantable electronic devices is increasing, and there is a substantial number of patients who are on oral anticoagulant therapy. Prothrombin complex concentrate and other plasma concentrates are useful to deal with over-coagulated situations. The efficacy and safety of non-vitamin K antagonist oral anticoagulants have been proven in large phase III trials. The real-world data suggest even better outcomes with these agents compared to vitamin K antagonists.
A STEP-BY-STEP GUIDE TO IMPLEMENTING ADVANCED PHARMACY SERVICES IN COMMUNITY AND CLINIC SETTINGS Community and Clinical Pharmacy Services teaches pharmacy students and practicing pharmacists how to provide advanced levels of pharmacy services in community and clinic settings designed to help patients achieve specific health goals and treat common disease states. This unique text provides practical--rather than merely ideological--ways for pharmacists to utilize their extensive clinical knowledge and fill a major gap in American health care. It discusses barriers, necessary skills, required knowledge, and issues related to preparation, interventions, patient outcomes, economic aspects, and marketing considerations for therapeutic areas commonly addressed in the outpatient setting. The beginning of the book delves into the general management skills necessary to provide and implement advanced patient care services, including documentation, patient interviewing, and medication therapy management. Important chapters discuss disease states that would most likely be amenable to development of pharmacy services, including: Asthma Smoking Cessation Diabetes Hypertension Osteoporosis Obesity Also covered are immunizations, anticoagulation, and cardiometabolic services. The disease state chapters include learning aids such as summary points, first-hand accounts from experienced pharmacists who have implemented pharmacy services for that particular condition, a simulated patient case, and multiple-choice questions.