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Presenting the latest research in the biology of aging, this volume addresses important theoretical issues focusing on the basis for why humans live as long as they do. Expert authors combine three general paradigms of aging research: demographic studies, evolutionary studies, and studies of biological mechanisms. Topics explored include: Why does aging occur? Cellular aging Models in aging research Modern approaches to the mechanisms of aging The genetics of behavioral aging
This volume examines the importance of time and place, as applied to aging families. In the first section, chapters focus on the temporal dimension of intergenerational relations using frameworks from human development, sociology, social history, and social psychology. The second section focuses on the social ecology of intergenerational relations in terms of the national contexts within which families are embedded. The contributors demonstrate how the social, cultural, historical, and institutional forces that orient older and younger family members toward each other in both structured and adaptive ways.
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Enormous advances in our knowledge of genetic contributions to aging and disease, and in our understanding of the potential for manipulation of the aging process, have taken place during the past 20 years. This is the first volume in decades to consolidate this research in one place. It provides a broad and current overview of the most promising advances in genetic research on aging, current understanding of genetic contributions to the basic processes of aging, and age-related disease. The Review focuses on the aging process from lower organisms to man, and is organized in ascending order of biological complexity starting with stem cells and progressing through worms, flies, mice, and humans. Where relevant, the Review also includes information about yeasts and non-human primates. The research presented in the Review uses a species-comparative approach that makes finding cross species similarities (gene conservation) and differences (gene differentiation) apparent. This approach reflects the way in which the field is organized, making it highly useful for investigators who want quick access and a concise summary of a particular topic. Key Features: Provides state-of-the-art information about promising advances in genetic research on aging Comprises the first comprehensive volume regarding genetic research about aging in decades Authored by leading scholars in the field Disseminates enormous advances in our understanding of the aging process
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It is increasingly recognized that an individual's experience of old age is fundamentally influenced by their earlier life experiences. This volume of the Annual Review of Gerontology and Geriatrics begins with an overview of the theoretical underpinnings of both the Life Span and the Life Course perspectives on health disparities in aging populations, examining them in the context of a changing structure of society. This volume focuses on morbidities in general as well as specific morbidities such as diabetes, cardiovascular disease and hypertension, giving special attention to life-time influences on cognition and functional abilities. Finally, this new volume addresses broader policy issues with relation to Life Span and Life Course perspectives on aging. Key Features: Addresses an important topic of increasing relevance. Addresses the issue of disparities from genes to geography Presents traditional and emerging scientific perspectives
Developed countries and certain regions of economically emerging nations have displaying a rapidly growing population of the oldest-oldónonagenarians, centenarians, and supercentenarians. As this trend continues, we must redirect some of our research on aging to the experience of advanced old age and discovering individual and community factors that improve the quality of life during this life stage. This state-of-the science, multidisciplinary Annual provides a comprehensive discussion of the factors promoting healthy survival and/or ensuring a good quality of life for the oldest elderly. It features an international representation that includes Denmark, Finland, France, Italy, the Netherlands, the United Kingdom, Sweden, Japan, and North America. The Annual disseminates the most current research regarding this population and notes gaps in our knowledge. The book addresses ongoing demo-epidemiological changes regarding longevity, estimates of oldest-old populations, and prevalence of chronic and degenerative diseases, frailty, and old-age dependency. The meaning of healthy longevity as a theoretical concept is explored. Grounded in the fundamental issue of whether or not the prevalence of poor health or poor quality of life inevitably increases with age, recent research and ongoing studies from a variety of perspectives are presented from several nations. The book clarifies the known and hypothetical factors favoring healthy longevity, from genes to social integration. Additionally, chapters explore gender differences in age trajectories and changes over time. Special attention is given to the social and cognitive dimensions of healthy longevity. Key Features: Disseminates new scholarly research about a rapidly growing segment of the populationóthe oldest old Offers multidisciplinary and international perspectives about the factors that promote healthy survival and improve quality of life Addresses the social and cognitive dimensions of healthy longevity Provides important information regarding health care costs for this population Includes the research of seasoned and emerging scholars
This volume of the Annual Review of Gerontology and Geriatrics helps readers see the local problem and concern of aging as a global epidemic affecting all areas of the health care workplace. It is written for expert administrative leaders and policymakers who can help make a difference at both local and regional levels.
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