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This report summarizes the work done at the Williams Laboratory of the University of Minnesota during the period from August 1975 through 1976. The major part of this report describes recent results and work in progress in the nuclear physics research program. Work involving beams of light ions and light element targets is followed by work using heavier targets and then the experiments using beams of oxygen and fluorine ions. This heavy ion work occupies a larger portion of our program than in previous reports. The investigation of L-subshell ionization cross sections for heavy element targets and the studies of hyperfine splitting and isotope shifts are briefly described. The improved operation of the tandem Van de Graaff resulting from the installation of a new set of acceleration tubes and other modifications is discussed. The current state of the testing of an on-line mass spectrometer and the installation of a source producing a beam of tritons is described. The final sections of this report list personnel, degrees granted, and publications of the staff. Separate indexing has been prepared for 10 sections of this report for appearance in ERA.