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ANIMAL HOUSE ON ACID is a memoir by Beverly Potter, a neighbor of the “most notorious housing unit on the face of the Earth.” Barrington Hall, a large student-run co-op on the Southside of the University a few blocks off of Telegraph Avenue, was Berkeley’s last outpost of the ‘60s. Barringtonians, as they called themselves, held fast to the culture of sex, drugs, and rock ‘n’ roll long after it had ceased to be fashionable, and clung to the sanctity of individual expression—even to the point of covering up not only illegal but genuinely harmful acts with a cloak of silence, know as “Onngh Yonngh”, which stated: Those who know, don't tell' those who tell, don't know. Inside Barrington Hall, youth rebellion never grew old, because each year it was replenished with a new crop of eighteen-year-olds, sorry to have missed the ‘60s and glad to find a small chunk of it still alive just down the street from People’s Park on Dwight Way. Barrington became a victim of its own mythology: with a house culture dedicated to outrage, it eventually outraged all, even its natural allies. Established as a co-op in the 1930s, by 1980 Barrington had become a continuing disaster for the USCA [University Students Coop Association]. Known internationally for live punk rock, LSD parties called “wine dinners” featuring acid-spiked wine punch, open drug use, heroin use and over-doses, crashers and haven for under-age run-aways, activism and anarchy, raucous parties, kids going off the four-story roof, along with disputes with neighbors and investigations by the City Council. Barrington sapped the patience of everyone involved. Finally after a neighbor group took Barrington to arbitration, and three City investigations, and PACT - Parents and Children Together attempts to control the raucous behavior, Potter filed a lawsuit. Then the death threats rained down upon her. Barrington Hall was boarded up in March 1990 -- 24 years ago. Yet, it’s spirit and romance lives on. Today, in July 2014, there is a large memorial poster in the window of Rasputin Music on Telegraph Avenue honoring Barrington Hall, calling it a “petri dish of early San Francisco Bay Area Punk Rock.” [https://www.flickr.com/photos/wallyg/9583462218/] Dead Kennedys, Green Day, Primus and other popular Punk groups played regularly at Barrington. There are several chat sites developed to Barrington along with annual reunions. Les Claypool of the Punk group, Primus, wrote one of the many songs about Barrington. [https://www.youtube.com/watch?v=fNrTKhGbqi4] Barrington was known for its floor to ceiling murals through-out the building -- all four floors. [https://www.youtube.com/watch?v=YqMVyNq189o] Barringtonians routinely painted graffiti messages to and about Potter on the outside of the building, including "Beverly gives good head" which was listed in her lawsuit as a cause of action. ANIMAL HOUSE ON ACID is packed with side stories. One is about the dope book publishers suing the dope den. Sebastian Orfali and Beverly Potter, publishers of Ronin Publishing, which arose the ashes of the 1970’s break-through And/Or Press, were neighbors -- literally under the windows of Barrington. When the media learned that Ronin (and And/Or before it) published marijuana and psychedelics subjects, a KCBS commentator remarked about Orfali, “Isn’t that the pot calling the kettle black?” The 1989 photo featured in the Barrington Hall Wikipedia is 30 feet from Potter's house. [http://en.wikipedia.org/wiki/Barrington_Hall_(Berkeley,_California)] In 1990, Barrington Hall was to be closed for good. 18 students - "the holdovers" - refused to leave and were being evicted. March 3, 1990, a poetry reading escalated into a full blown riot -- with Berkeley Riot Squad trucks sweeping the streets and riot police swinging clubs. There was a 20 foot bonfire in front of the Haste Street entrance - and Potter's house. ANIMAL HOUSE ON ACID is Potter's memoir of a truly long, strange trip, which she tells in a scrapbook-like format, composed of local newspaper stories, City reports, incident notes, posters, photographs, stitched together with Potter's retelling of wild tales -- even by Berkeley standards.
Following the leader of the notorious "Merry Pranksters" from his birth in Colorado to his literary success and the cross-country journey that inspired the "Electric Kool-Aid Acid Test," this candid biography chronicles the life and times of 1960s cultural icon Ken Kesey. Presenting an incisive analysis of the author who described himself as "too young to be a beatnik, and too old to be a hippie,” this account conducts a mesmerizing journey from author Mark Christensen's point of view, who grew up in Southern California and migrated to Oregon to be part of the Kesey "flock." From interviews with family members and those within his inner circle, this exploration reveals the bestselling author of One Flew Over the Cuckoo's Nest in his many forms, placing him within the framework of his time, his generation, and the zeitgeist of the psychedelic era.
This book provides a meticulous view on methodological drug discovery and development insights from bench to bedside. The current book threads almost each step encompassing drug the discovery and development of a molecule. The chapters focus on computational modus operandi, pharmacological optimization approaches, modern high-throughput screening methods and in-vitro procedures, role of structural biologists in drug discovery and development, medicinal chemistry approaches for drug design, formulation and drug delivery, in-vivo evaluations of candidate molecules, clinical trial procedures and others. The book also covers specific case studies, regulatory approval proceedings, and industrial view point alongside the aforementioned conceptual layout. And at the same time, the volume integrates medical, biological, medicinal, pharmacological and computational streams, and it is suggested as an ideal guideline to a wide audience including molecular biologists, biochemist, pharmacologists, medicinal chemist, toxicologists, drug discovery and development researchers, and all other students interested in these disciplines.
When a dose of drug is administered, three main phases of drug action may be distingushed. In the "pharmaceutical" phase the dosage form disintegrates, the active substance dissolves and becomes available for absorption. The second phase ("pharmaco kinetic" phase) includes absorption, distribution, metabolism, and excretion. That fraction of the dose which finally reaches the circulation after absorption will be available for biological action in the third, or "pharmacodynamic" phase when the drug reaches the target tissues and a drug-receptor interaction takes place. The objectives in studies of drug metabolism are: (a) to identify the pathways by which drugs are transformed in the body; (b) to ascertain quantitatively the importance of each pathway and intermediate; (c) to identify and quantify endogenous constituents influenced by the drug or its metabolites which may interfere with common metabolic processes. Since metabolites usually differ from their precursors by only a single chemical group, the resulting metabolic pathways generally consist of a series of closely related compounds. Mass spectrometry is uniquely suited for the analysis of drugs and metabolites for several reasons: only a minimal amount of sample preparation is needed, closely related compounds can be analyzed in a single step, structures can often be deduced directly from the mass spectra without the need for pure reference spectra, and constituents can be quantified with relative ease even when present in fractional nanogram quantity.
This book is compilation of research papers presented by scholars of international repute at International Ayurveda conference held at Pune , India on 29th, 30th & 31st January 1993 under pesidentship of Prof.P.H. Kulkarni. 55 papers were presented. Some of them are as follows : Clinical case studies, laboratory experiments, medicinal preparations, medicinal plants in Arunachal Pradesh ,India and Nrw Zealand, Pollution and health for all , Role of media in health area, sports medicine , Tridosha and blood groups , cosmetology in Ayurveda, Mantra vidnyan , Integrated Ayurveda treatment, Langbank / fasting , Kuti praveshik Rasayana etc.
Diabetes mellitus is a chronic metabolic disease characterized by elevated blood glucose levels, which severely affects the quality of life and survival of patients. The latest data from the International Diabetes Federation showed that there are approximately 537 million diabetic patients globally in 2021, and it is expected to reach 783 million by 2045. The treatment regime of diabetic patients mainly refers to the management of blood glucose and its complications. At present, typical hypoglycemic medications include insulin and non-insulin hypoglycemic drugs, which can be subdivided into a-glucosidase inhibitors, metformin, thiazolidinediones, sulfonylureas, glinides, DPP-4i, GLP-1RA, and SGLT-2i. Diabetic patients with poor islet function usually require insulin replacement, but the majority of patients fail to meet ideal therapeutic targets with multiple hypoglycemic drug combinations (including insulin). Furthermore, poor glycemic control is closely associated with an increased risk of diabetes complications, consequently an increased rate of mortality. More recently, promising new drugs and therapies emerged, which have many other important benefits beyond glucose-lowering. In addition, some traditional Chinese medicine have gradually revealed their therapeutic advantages. All of them provide more choices for the treatment of diabetes patients.
The creator of Animal House at last tells the real story of the fraternity that inspired the iconic film -- a story far more outrageous and funny than any movie could ever capture.
Ron and Jill, after six months together, discovered the house of their dreams: a landmark Victorian row house that had belonged to a notorious fraternity in Baltimore. Unfortunately, it was now a condemned, abandoned property. But Jill wanted the house and Ron wanted Jill. Beyond the wall-to-wall graffiti, collapsed fireplaces and banisters, and three dumpsters worth of trash, the couple envisioned this as their future dream home. So Ron bought the 4,500-square-foot ruin, despite the fact that neither Ron nor Jill knew anything about home renovation, and that the project might ruin them both financially and emotionally. A book for lovers, dreamers, and do-it-yourselfers, From Animal House to Our House recounts Ron and Jill’s decade-long adventure in house restoration, offering inspiration, insight, and hilarity as they hammer away at the American dream of home ownership and true love.
This book is compilation of 51 research articles covering many aspects of Liver diseases with view of modern advances and Ayurveda. There are articles related to Homeopathy, Unani medicine, Horoscope and liver health. Clinical and experimental trials on drugs for Cirrhosis, Hepatitis etc.