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In this book a distinguished scientist-historian offers a critical account of how biochemistry and molecular biology emerged as major scientific disciplines from the interplay of chemical and biological ideas and practice. Joseph S. Fruton traces the historical development of these disciplines from antiquity to the present time, examines their institutional settings, and discusses their impact on medical, pharmaceutical, and agricultural practice.
An examination of the sources Helmholtz drew upon for his formulation of the conservation of energy and the impact of his work on nineteenth-century physics. In 1847, Herman Helmholtz, arguably the most important German physicist of the nineteenth century, published his formulation of what became known as the conservation of energy--unarguably the most important single development in physics of that century, transforming what had been a conglomeration of separate topics into a coherent field unified by the concept of energy. In Helmholtz and the Conservation of Energy, Kenneth Caneva offers a detailed account of Helmholtz's work on the subject, the sources that he drew upon, the varying responses to his work from scientists of the era, and the impact on physics as a discipline. Caneva describes the set of abiding concerns that prompted Helmholtz's work, including his rejection of the idea of a work-performing vital force, and investigates Helmholtz's relationship to both an older generation of physicists and an emerging community of reformist physiologists. He analyzes Helmholtz's indebtedness to Johannes Müller and Justus Liebig and discusses Helmholtz's tense and ambivalent relationship to the work of Robert Mayer, who had earlier proposed the uncreatability, indestructibility, and transformability of "force." Caneva examines Helmholtz's continued engagement with the subject, his role in the acceptance of the conservation of energy as the central principle of physics, and the eventual incorporation of the principle in textbooks as established science.