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On May 4-8, 1987, a NATO Advanced Research Workshop on the Analytical Uses of Immobilized Biological Compounds was held in Florence, Italy. The Director of the Workshop was Professor George G. Guilbault of the University of New Orleans, and the Co-Director was Professor Marco Mascini of the University of Florence It vas the purpose of this meeting to assemble scientists from all NATO Countries with an interest in immobilized biological compounds. to discuss - methods of immobilization - properties of immobilized compounds - enzyme electrodes and biosensors - optical devices utilizing immobilized enzymes - microbial sensors and clinical uses of immobilized enzymes - flow injection analysis using enzymes - immobilized biological compounds in chemical defense detection - pharmaceutical analysis - uses in industrial analysis - enzyme reactors - air pollution detectors - immunosensors - medical uses and applications - solid state and FET sensors Goals to be achieved by the conference were - to permit an exchange of views and experience in all these areas - to review and critically assess the state-of-the-art in these fields - to set guidelines for future research and establish collaborative projects between scientists in NATO laboratories in the above areas. Thirty-seven lectures were given by 36 speakers in all of the above areas.
In Uses of Immobilized Biological Compounds the reader will find a comprehensive survey of the field written by acknowledged experts who met in Brixen, Italy, between May 9 and 14, 1993 for a NATO Advanced Research Workshop devoted to the topic. The resulting volume presents a critical review of the latest results in the area and sets guidelines for future research. The 53 reports presented here cover: (A) General Aspects of Immobilizing Biological Compounds; (B) Medical, Clinical and Pharmaceutical Applications; (C) Electrochemical Biosensors; (E) Defense Applications; (F) Immunosensors and Receptors; (G) Food, Environmental, Clinical and Analytical Applications; and (H) Biotechnology and Marketing. In short, all aspects of the area are presented, in a compact format which will appeal to undergraduates, technicians, and professional scientists in the food, clinical, environmental, pharmaceutical and industrial fields.
Since the publication of the first edition of Chemistry of Protein Conjugation and Cross-Linking in 1991, new cross-linking reagents, notably multifunctional cross-linkers, have been developed and synthesized. The completion of the human genome project has opened a new area for studying nucleic acid and protein interactions using nucleic acid cross
The enzyme acetylcholinesterase (AChE) has drawn the attention of scientist as it has played a striking role in Alzheimer's disease, Cardiac diseases and other diseases. A good discussion and overview document on AChE enzyme and its various aspects was felt lacking since a long time in the field of enzyme biochemistry as well as enzyme biotechnology and this publication fills this gap. Before this publication there was no data available on AChE enzyme inhibition, its kinetics, its peripheral sites, their role in catalytic and noncholinergic function of enzyme, ACh receptors, AChE and BuChE genes etc. All these topics together form a good basis for researchers and post graduate students in this field of interest. This book is a collection of recent advanced reports and data on AChE enzyme.
Presents a synopsis of the theoretical principles and practical experience concerning the interfacial behaviour of bioproducts. The volume offers an interdisciplinary approach to the subject that highlights the importance of interfacial phenomena in bioprocessing systems, and the tools used to study and interpret the phenomena. It contains coverage ranging from fundamentals of bioproduct and solid surface structure to the interactions of multicomponent mixtures in heterogeneous.
This reference text consists of contributed chapters by specialists directly carrying out research and development in this emerging field which joins advanced microelectronics with modern biotechnology. Chapters present novel biotechnology-based microelectronic instruments, such as those used for de
Bioelectrochemistry: Fundamentals, Experimental Techniques and Application, covers the fundamental aspects of the chemistry, physics and biology which underlie this subject area. It describes some of the different experimental techniques that can be used to study bioelectrochemical problems and it describes various applications of biolelectrochemisty including amperometric biosensors, immunoassays, electrochemistry of DNA, biofuel cells, whole cell biosensors, in vivo applications and bioelectrosynthesis. By bringing together these different aspects, this work provides a unique source of information in this area, approaching the subject from a cross-disciplinary viewpoint.
This book provides a concise and comprehensive introduction of polymer membranes' preparation, functionalization and applications in biotechniques including affinity membrane chromatography, membrane-based biosensor and membrane-based bioreactor.Following an introduction to the general concept of membrane separation in Chapter 1, preparation of polymeric membranes is discussed in Chapter 2. The book then describes in Chapter 3 membrane surface activation, which is a key step in ligand immobilizations. Chapter 4 focuses on ligand immobilization techniques and the organic chemistries behind them. Chapter 5 introduces the application of affinity membrane chromatography. Finally, in Chapter 6, membranes used in biosensors and gas sensors, enzymatic membranes used as biosensor, and membrane biosensor for waste water treatment will be discussed.A novel filter medium, i.e. nonwoven nanofiber membrane, and its preparation method, i.e. electrospinning technique, are also introduced in this book./a