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Bioinformatics, a field devoted to the interpretation and analysis of biological data using computational techniques, has evolved tremendously in recent years due to the explosive growth of biological information generated by the scientific community. Soft computing is a consortium of methodologies that work synergistically and provides, in one form or another, flexible information processing capabilities for handling real-life ambiguous situations. Several research articles dealing with the application of soft computing tools to bioinformatics have been published in the recent past; however, they are scattered in different journals, conference proceedings and technical reports, thus causing inconvenience to readers, students and researchers. This book, unique in its nature, is aimed at providing a treatise in a unified framework, with both theoretical and experimental results, describing the basic principles of soft computing and demonstrating the various ways in which they can be used for analyzing biological data in an efficient manner. Interesting research articles from eminent scientists around the world are brought together in a systematic way such that the reader will be able to understand the issues and challenges in this domain, the existing ways of tackling them, recent trends, and future directions. This book is the first of its kind to bring together two important research areas, soft computing and bioinformatics, in order to demonstrate how the tools and techniques in the former can be used for efficiently solving several problems in the latter. Sample Chapter(s). Chapter 1: Bioinformatics: Mining the Massive Data from High Throughput Genomics Experiments (160 KB). Contents: Overview: Bioinformatics: Mining the Massive Data from High Throughput Genomics Experiments (H Tang & S Kim); An Introduction to Soft Computing (A Konar & S Das); Biological Sequence and Structure Analysis: Reconstructing Phylogenies with Memetic Algorithms and Branch-and-Bound (J E Gallardo et al.); Classification of RNA Sequences with Support Vector Machines (J T L Wang & X Wu); Beyond String Algorithms: Protein Sequence Analysis Using Wavelet Transforms (A Krishnan & K-B Li); Filtering Protein Surface Motifs Using Negative Instances of Active Sites Candidates (N L Shrestha & T Ohkawa); Distill: A Machine Learning Approach to Ab Initio Protein Structure Prediction (G Pollastri et al.); In Silico Design of Ligands Using Properties of Target Active Sites (S Bandyopadhyay et al.); Gene Expression and Microarray Data Analysis: Inferring Regulations in a Genomic Network from Gene Expression Profiles (N Noman & H Iba); A Reliable Classification of Gene Clusters for Cancer Samples Using a Hybrid Multi-Objective Evolutionary Procedure (K Deb et al.); Feature Selection for Cancer Classification Using Ant Colony Optimization and Support Vector Machines (A Gupta et al.); Sophisticated Methods for Cancer Classification Using Microarray Data (S-B Cho & H-S Park); Multiobjective Evolutionary Approach to Fuzzy Clustering of Microarray Data (A Mukhopadhyay et al.). Readership: Graduate students and researchers in computer science, bioinformatics, computational and molecular biology, artificial intelligence, data mining, machine learning, electrical engineering, system science; researchers in pharmaceutical industries.
This book explains how the biological systems and their functions are driven by genetic information stored in the DNA, and their expression driven by different factors. The soft computing approach recognizes the different patterns in DNA sequence and try to assign the biological relevance with available information.The book also focuses on using the soft-computing approach to predict protein-protein interactions, gene expression and networks. The insights from these studies can be used in metagenomic data analysis and predicting artificial neural networks.
Bioinformatics, a field devoted to the interpretation and analysis of biological data using computational techniques, has evolved tremendously in recent years due to the explosive growth of biological information generated by the scientific community. Soft computing is a consortium of methodologies that work synergistically and provides, in one form or another, flexible information processing capabilities for handling real-life ambiguous situations. Several research articles dealing with the application of soft computing tools to bioinformatics have been published in the recent past; however, they are scattered in different journals, conference proceedings and technical reports, thus causing inconvenience to readers, students and researchers.This book, unique in its nature, is aimed at providing a treatise in a unified framework, with both theoretical and experimental results, describing the basic principles of soft computing and demonstrating the various ways in which they can be used for analyzing biological data in an efficient manner. Interesting research articles from eminent scientists around the world are brought together in a systematic way such that the reader will be able to understand the issues and challenges in this domain, the existing ways of tackling them, recent trends, and future directions. This book is the first of its kind to bring together two important research areas, soft computing and bioinformatics, in order to demonstrate how the tools and techniques in the former can be used for efficiently solving several problems in the latter.
This book presents a set of soft computing approaches and their application in data analytics, classification model, and control. The basics of fuzzy logic implementation for advanced hybrid fuzzy driven optimization methods has been covered in the book. The various soft computing techniques, including Fuzzy Logic, Rough Sets, Neutrosophic Sets, Type-2 Fuzzy logic, Neural Networks, Generative Adversarial Networks, and Evolutionary Computation have been discussed and they are used on variety of applications including data analytics, classification model, and control. The book is divided into two thematic parts. The first thematic section covers the various soft computing approaches for text classification and data analysis, while the second section focuses on the fuzzy driven optimization methods for the control systems. The chapters has been written and edited by active researchers, which cover hypotheses and practical considerations; provide insights into the design of hybrid algorithms for applications in data analytics, classification model, and engineering control.
The study of biological data is constantly undergoing profound changes. Firstly, the volume of data available has increased considerably due to new high throughput techniques used for experiments. Secondly, the remarkable progress in both computational and statistical analysis methods and infrastructures has made it possible to process these voluminous data. The resulting challenge concerns our ability to integrate these data, i.e. to use their complementary nature effectively in the hope of advancing our knowledge. Therefore, a major challenge in studying biology today is integrating data for the most exhaustive analysis possible. Biological Data Integration deals in a pedagogical way with research work in biological data science, examining both computational approaches to data integration and statistical approaches to the integration of omics data
This volume provides a collection of sixteen articles containing review and new material. In a unified way, they describe the recent development of theories and methodologies in pattern recognition, image processing and vision using fuzzy logic, artificial neural networks, genetic algorithms, rough sets and wavelets with significant real life applications. The book details the theory of granular computing and the role of a rough-neuro approach as a way of computing with words and designing intelligent recognition systems. It also demonstrates applications of the soft computing paradigm to case based reasoning, data mining and bio-informatics with a scope for future research. The contributors from around the world present a balanced mixture of current theory, algorithms and applications, making the book an extremely useful resource for students and researchers alike. Contents: Pattern Recognition: Multiple Classifier Systems; Building Decision Trees from the Fourier Spectrum of a Tree Ensemble; Clustering Large Data Sets; Multi-objective Variable String Genetic Classifier: Application to Remote Sensing Imagery; Image Processing and Vision: Dissimilarity Measures Between Fuzzy Sets or Fuzzy Structures; Early Vision: Concepts and Algorithms; Self-organizing Neural Network for Multi-level Image Segmentation; Geometric Transformation by Moment Method with Wavelet Matrix; New Computationally Efficient Algorithms for Video Coding; Soft Computing for Computational Media Aesthetics: Analyzing Video Content for Meaning; Granular Computing and Case Based Reasoning: Towards Granular Multi-agent Systems; Granular Computing and Pattern Recognition; Case Base Maintenance: A Soft Computing Perspective; Real Life Applications: Autoassociative Neural Network Models for Pattern Recognition Tasks in Speech and Image; Protein Structure Prediction Using Soft Computing; Pattern Classification for Biological Data Mining. Readership: Upper level undergraduates, graduates, researchers, academics and industrialists.
First title to ever present soft computing approaches and their application in data mining, along with the traditional hard-computing approaches Addresses the principles of multimedia data compression techniques (for image, video, text) and their role in data mining Discusses principles and classical algorithms on string matching and their role in data mining
Publisher Description
This book plays a significant role in improvising human life to a great extent. The new applications of soft computing can be regarded as an emerging field in computer science, automatic control engineering, medicine, biology application, natural environmental engineering, and pattern recognition. Now, the exemplar model for soft computing is human brain. The use of various techniques of soft computing is nowadays successfully implemented in many domestic, commercial, and industrial applications due to the low-cost and very high-performance digital processors and also the decline price of the memory chips. This is the main reason behind the wider expansion of soft computing techniques and its application areas. These computing methods also play a significant role in the design and optimization in diverse engineering disciplines. With the influence and the development of the Internet of things (IoT) concept, the need for using soft computing techniques has become more significant than ever. In general, soft computing methods are closely similar to biological processes than traditional techniques, which are mostly based on formal logical systems, such as sentential logic and predicate logic, or rely heavily on computer-aided numerical analysis. Soft computing techniques are anticipated to complement each other. The aim of these techniques is to accept imprecision, uncertainties, and approximations to get a rapid solution. However, recent advancements in representation soft computing algorithms (fuzzy logic,evolutionary computation, machine learning, and probabilistic reasoning) generate a more intelligent and robust system providing a human interpretable, low-cost, approximate solution. Soft computing-based algorithms have demonstrated great performance to a variety of areas including multimedia retrieval, fault tolerance, system modelling, network architecture, Web semantics, big data analytics, time series, biomedical and health informatics, etc. Soft computing approaches such as genetic programming (GP), support vector machine–firefly algorithm (SVM-FFA), artificial neural network (ANN), and support vector machine–wavelet (SVM–Wavelet) have emerged as powerful computational models. These have also shown significant success in dealing with massive data analysis for large number of applications. All the researchers and practitioners will be highly benefited those who are working in field of computer engineering, medicine, biology application, signal processing, and mechanical engineering. This book is a good collection of state-of-the-art approaches for soft computing-based applications to various engineering fields. It is very beneficial for the new researchers and practitioners working in the field to quickly know the best performing methods. They would be able to compare different approaches and can carry forward their research in the most important area of research which has direct impact on betterment of the human life and health. This book is very useful because there is no book in the market which provides a good collection of state-of-the-art methods of soft computing-based models for multimedia retrieval, fault tolerance, system modelling, network architecture, Web semantics, big data analytics, time series, and biomedical and health informatics.
An invaluable tool in Bioinformatics, this unique volume provides both theoretical and experimental results, and describes basic principles of computational intelligence and pattern analysis while deepening the reader's understanding of the ways in which these principles can be used for analyzing biological data in an efficient manner. This book synthesizes current research in the integration of computational intelligence and pattern analysis techniques, either individually or in a hybridized manner. The purpose is to analyze biological data and enable extraction of more meaningful information and insight from it. Biological data for analysis include sequence data, secondary and tertiary structure data, and microarray data. These data types are complex and advanced methods are required, including the use of domain-specific knowledge for reducing search space, dealing with uncertainty, partial truth and imprecision, efficient linear and/or sub-linear scalability, incremental approaches to knowledge discovery, and increased level and intelligence of interactivity with human experts and decision makers Chapters authored by leading researchers in CI in biology informatics. Covers highly relevant topics: rational drug design; analysis of microRNAs and their involvement in human diseases. Supplementary material included: program code and relevant data sets correspond to chapters.