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This book is designed as an introductory text in neuroendocrinology; the study of the interaction between the brain and endocrine system and the influence of this on behaviour. The endocrine glands, pituitary gland and hypothalamus and their interactions and hormones are discussed. The action of steroid and thyroid hormone receptors and the regulation of target cell response to hormones is examined. The function of neuropeptides is discussed with respect to the neuroendocrine system and behaviour. The neuroimmune system and lymphokines are described and the interaction between the neuroendocrine and neuroimmune systems discussed. Finally, methods for studying hormonal influences on behaviour are outlined. Each chapter has review and essay questions designed for advanced students and honours or graduate students with a background in neuroscience, respectively.
How does the brain regulate sexual behavior, or control our body weight? How do we cope with stress? Addressing these questions and many more besides, this thoroughly revised new edition reflects the significant advances that have been made in the study of neuroendocrinology over the last twenty years. The text examines the importance of the hypothalamus in regulating hormone secretion from the endocrine glands, describing novel sites of hormone release including bone, heart, skeletal muscle and liver. The role of steroid hormone, neurotransmitter and peptide receptors, and the molecular responses of target tissues, is integrated into the discussion of the neuroendocrine brain, especially through changes in gene expression. Particular attention is attached to neuropeptides, including their profound influence on behavior. Complete with new full-color figures throughout, along with review and essay questions for each chapter, this is an ideal resource for undergraduate and graduate students of neuroscience, psychology, biology and physiology.
A concise and innovative account of clinical neuroendocrine disorders and the key principles underlying their diagnosis and management.
The Third Edition of An Introduction to Behavioral Endocrinology retains all the features of the bestselling prior editions, and provides an updated, integrated presentation of the study of hormone- behaviour interactions.
Neuroendocrinology underpins fundamental physiological, molecular, biological, and genetic principles such as the regulation of gene transcription and translation. This handbook highlights the experimental and technical foundations of each area's major concepts and principles.
Our world and bodies are becoming increasingly polluted with chemicals capable of interfering with our hormones and thus, possibly, our present and future neural and mental health. As authors Heather Patisaul and Scott Belcher outline, there is a large lack of data and evidence in this causal relationship, which begs a need for further study to accelerate progress in the endocrinology and neuroendocrinology fields. Endocrine Disruptors, Brain, and Behavior focuses on if and how these chemicals, known as endocrine disrupting compounds (EDCs), affect the development and function of the brain and might be contributing to neural disorders rapidly rising in prevalence. The book provides an overall synthesis of the EDC field, including its historical roots, major hypotheses, key findings, and research gaps. The authors explain why even the concept of endocrine disruption is controversial in some circles, how differing definitions of endocrine disruption and what constitutes an "adverse" outcome on the brain shape public policy, and where the current capacity by different stakeholders (industry, academia, regulatory agencies) to evaluate chemicals for safety in a regulatory context begins and ends. The book concludes with suggestions for future research needs and a summary of emerging technology which might prove capable of more effectively evaluating existing and emerging chemicals for endocrine disrupting properties. As such, it provides the context for interdisciplinary and innovative input from a broad spectrum of fields, including those well-schooled in neuroscience, evolutionary biology, brain, behavior, sex differences, and neuroendocrinology.
The Routledge International Handbook of Social Neuroendocrinology is an authoritative reference work providing a balanced overview of current scholarship spanning the full breadth of the rapidly developing field of social neuroendocrinology. Considering the relationships between hormones, the brain, and social behavior, this collection brings together groundbreaking research in the field for the first time. Featuring 39 chapters written by leading researchers, the handbook offers impressive breadth of coverage. It begins with an overview of the history of social neuroendocrinology before discussing its methodological foundations and challenges. Other topics covered include state-of-the-art research on dominance and aggression; social affiliation; reproduction and pair bonding (e.g., sexual behavior, sexual orientation, romantic relationships); pregnancy and parenting; stress and emotion; cognition and decision making; social development; and mental and physical health. The handbook adopts a lifespan approach to the study of social neuroendocrinology throughout, covering the role that hormones play during gestation, childhood, adolescence, and adulthood. It also illustrates the evolutionary forces that have shaped hormone-behavior associations across species, including research on humans, non-human primates, birds, and rodents. The handbook will serve as an authoritative reference work for researchers, students, and others intrigued by this topic, while also inspiring new lines of research on interactions among hormones, brain, and behavior in social contexts.
Model Animals in Neuroendocrinology: From Worm to Mouse to Man offers a masterclass on the opportunities that different model animals offer to the basic understanding of neuroendocrine functions and mechanisms of action and the implications of this understanding. The authors review recent advances in the field emanating from studies involving a variety of animal models, molecular genetics, imaging technologies, and behavior assays. These studies helped unravel mechanisms underlying the development and function of neuroendocrine systems. The book highlights how studies in a variety of model animals, including, invertebrates, fish, birds, rodents and mammals has contributed to our understanding of neuroendocrinology. Model Animals in Neuroendocrinology provides students, scientists and practitioners with a contemporary account of what can be learnt about the functions of neuroendocrine systems from studies across animal taxonomy. This is the seventh volume in the Masterclass in Neuroendocrinology Series, a co-publication between Wiley and the INF (International Neuroendocrine Federation) that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology.
Traditionally, endocrinology textbooks have been either short notes or multi-author, multi-volume monster, all of which present clinical material last and often only briefly. Endocrinology is different and used real cases to lead readers into the text and then describes the biochemistry, physiology, and anatomy they need to understand the case. The