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An Introduction to Mechanisms in Pharmacology and Therapeutics aims to provide some extra information and background reading on modes of action of drugs, but it is not meant to replace existing pharmacology textbooks. It also attempts to show the connection between cell biology and the practice of clinical medicine. This book is organized into 13 chapters that discuss drug-receptor interactions and the influence of drugs on the nervous, respiratory, circulatory, and alimentary systems. They also explain the concepts of pharmacogenetics, intracellular control mechanisms, chemotherapy, and the different types of drugs. This book will be of interest to preclinical and clinical medical students and those preparing for Bachelor of Science degree in Pharmacology and others interested in understanding how drugs work.
This book covers all the pharmacology you need, from basic science pharmacology and pathophysiology, through to clinical pharmacology to therapeutics, in line with the integrated approach of new medical curricula. The first section covers the basic principles, and the rest is organised by body systems. The book ends with sections on toxicity and prescribing practice. Integrates basic science pharmacology, clinical pharmacology and therapeutics Brief review of pathophysiology of major diseases Case histories and multiple choice questions (and answers) Tabular presentation of all common drugs within each class Section on further reading Kinetics chapter simplified with more practical examples Includes more on genetic issues Drug tables made more concise to make information more accessible Fully updated to reflect current clinical practice
**Selected for Doody's Core Titles® 2024 in Pharmacology**Atkinson's Principles of Clinical Pharmacology, Fourth Edition is the essential reference on the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This well-regarded survey continues to focus on the basics of clinical pharmacology for the development, evaluation and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the fourth edition has been thoroughly updated to provide readers with an ideal reference on the wide range of important topics impacting clinical pharmacology. - Presents the essential knowledge for effective practice of clinical pharmacology - Includes a new chapter and extended discussion on the role of personalized and precision medicine in clinical pharmacology - Offers an extensive regulatory section that addresses US and international issues and guidelines - Provides extended coverage of earlier chapters on transporters, pharmacogenetics and biomarkers, along with further discussion on "Phase 0" studies (microdosing) and PBPK
Basic Pharmacology, Third Edition aims to present accounts of drug actions and their mechanisms in a compact, inexpensive, and updated form, and explain the basis of the therapeutic exploitation of drugs. This book is divided into sections that follow a particular theme and is introduced by the relevant pharmacological general principles. In each section, the major groups of drugs related to the theme are discussed with detailed expositions of the important “type substances. Drugs of lesser importance are placed in proper context. A list of abbreviations that are referenced throughout the book is provided after the introduction. An index is also included at the end. This edition is designed to help students taking pharmacology, including medical students of subjects affiliated to medicine, to appreciate the rationale underlying the uses of drugs in therapeutics.
This best selling book delivers the most current, complete, and authoritative pharmacology information to students and practitioners. All sections are updated with new drug information and references. New! Many new figures and diagrams, along with boxes of highlighted material explaining the "how and why" behind the facts.
Focusing on the essential aspects of pharmacology you need to know, Brody‘s Human Pharmacology, 6th Edition, keeps you fully up to date with all that’s new in the field. Streamlined content, a new organizational approach, and thoroughly updated information ensure your grasp of key concepts and prepare you for exams. Nearly 500 full-color illustrations explain important processes, while color-coded boxes for major drugs, therapeutic overviews, clinical problems, and trade names reinforce your mastery of the information. The 6th Edition of this easy-to-use text is now fully up to date with: NEW chapter devoted entirely to pharmacogenomics and personalized medicine. NEW chapter on cannabinoids and their use for pain and other disorders, in light of recent legalization in many states. NEW chapters on recent developments in the treatment of Alzheimer's disease, ADHD and the latest treatments for HIV. NEW section on pain management. NEW section in each chapter covering "Clinical Relevance for Healthcare Professionals" that provides important information specific to physical therapists, dentists and dental hygienists, and many other medical professionals. Plus these student-friendly features: A new organizational approach, focusing on integration and systems-based learning. Contributions from leading faculty who cover the most important aspects of pharmacology necessary for a basic understanding of the subject, including concepts, clinical applications, and side effects. USMLE-style self-assessment questions at the end of every chapter, answers and rationales in the Appendix. Evolve Instructor Resources, including a downloadable image and test bank, are available to instructors through their Elsevier sales rep or via request at: https://evolve.elsevier.com
Now in its third edition, Principles of Pharmacology presents content in a conceptual framework that maximizes understanding and retention and minimizes rote memorization. It takes students "beyond the disease" and deep into physiologic, biochemical, and pathophysiologic systems where drugs activate or inhibit these systems by interacting with molecular and cellular targets. This unique approach ensures understanding of the mechanisms of drug actions on the body, and ultimately, in treating the human patient. Ideal for introductory pharmacology courses that emphasize critical thinking, molecular understanding, systems-based integration, and clinical preparation, the text: Features chapter-opening clinical cases and questions to establish a context for the discussion and the answers that follow Presents signature drug summary tables, updated and organized by mechanism of action, with information on clinical applications, adverse effects, contraindications, and therapeutic considerations Incorporates NEW full-color illustrations throughout, suiting the needs of visual learners and more effectively presenting concepts covered in the narrative Integrates timely content, including recently approved drugs as well as current research on drug mechanisms of action Delivers course and review material appropriate for students through a uniquely collaborative authorship consisting of medical students, residents, and faculty
Building on the strengths of previous editions, the Sixth Edition of Modern Pharmacology with Clinical Applications continues to provide an up-to-date and comprehensive textbook for students of pharmacology. Focusing on the clinical application of drugs within a context of the major principles of pharmacology, this text supplies both students and faculty with an introduction to modern pharmacotherapeutics.
Standard medicinal chemistry courses and texts are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that allow the reader to extrapolate to many related classes of drug molecules. The Second Edition reflects the significant changes in the drug industry over the past decade, and includes chapter problems and other elements that make the book more useful for course instruction. - New edition includes new chapter problems and exercises to help students learn, plus extensive references and illustrations - Clearly presents an organic chemist's perspective of how drugs are designed and function, incorporating the extensive changes in the drug industry over the past ten years - Well-respected author has published over 200 articles, earned 21 patents, and invented a drug that is under consideration for commercialization