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Documenting the scope and depth of the major achievements in cardiology during the last 40 years, An Era in Cardiovascular Medicine presents previously unpublished articles as well as papers from the 40th Anniversary Symposium of the American College of Cardiology. Unusually comprehensive and authoritative, this volume highlights some of the trail-blazing advances in cardiovascular knowledge and their application to patient care. The volume also looks to the future and suggests that a new era is in the making - one in which molecular cardiology, the understanding of dynamic patterns of disease made possible through the study of nonlinear systems, and decision-making based on probability theory will in the future exert a substantial influence on clinical practice. More than 60 renowned authorities, many of whom are pioneers in their areas of specialization, have contributed to this volume.
This guide is directed at the multi-disciplinary team dealing with cardiac rehabilitation. It is a practical handbook for everyday professionals on what they should do following cardiac events and return to work. It is adapted to the needs of cardiac rehabilitation centers. · Key publication from the European Association of Preventive Cardiology (EAPC) · Companion handbook to The ESC Handbook of Preventive Cardiology: Putting Prevention into Practice This handbook is directed at cardiologists in training and practice, specialist (cardiac) nurses, technicians, exercise physiologists and other healthcare professionals involved in the multidisciplinary process of cardiac rehabilitation · Practical user-friendly handbook style presentation · Covers the complete spectrum of rehabilitation care · Key team members address key issues - smoking, diet and physical activity · Focus on high risk patients (family approach)
Written, reviewed, and edited in a collaborative effort by cardiology fellows and faculty of one of the most prestigious academic centers in the country, this concise volume gives cardiology fellows the book they have long needed. Keeping coverage of the underlying pathophysiology and mechanism of disease to a minimum, the authors focus on the diagnosis and treatment of cardiac disorders. Practical and easily accessible at the time of decision making, the book relays important concepts through concise and to-the-point pearls and by utilizing algorithm charts and illustrations.
Pediatric cardiology is celebrating in the 1990s the 50th anniversary of the beginnings of the age of therapy. This informal `history' describes how the discipline grew from the era of pathologic anatomy to the dawn of therapy, the beginnings of closed heart surgery between 1939 and 1945. That dawn ushered in a remarkable half century of change and growth, leading from clinicophysiologic correlations through the start of open heart surgery in the 1950s. The text celebrates some of the achievements of this vivid and heroic age, and describes how, in the mid 1970s, new surgical and medical approaches, including prostaglandins and Doppler echocardiography, led to successful cardiac treatment in infancy, the `infant era'. Interventional cardiology and the study of childhood arrhythmias began. Now, in the 1990s, a new era emphasising molecular biology and cardiac development is growing from the tools and concepts of the past. The four eras have focused on pathologic anatomy, clinicophysiologic correlations and surgery, heart problems in infancy, and now the developing heart. In each era there have been advances in the four domains of pediatric cardiology, the heart before birth, the normal heart, heart disease and defects, and preventive cardiology. Growth in knowledge has been both episodic and dramatic, yet not a picture of unalloyed achievement. The later chapters discuss some of the problems beginning to be recognised in the new and current `developmental era'. The pioneers of pediatric cardiology, both men and women, are more than eponyms, for each used in new and original ways the tools and concepts available in their era. The interaction of tools and concepts is a theme in this book. Just as the tool of the stethoscope was vital in delineating the clinical profile of ventricular septal defect and patent ductus, the fluoroscope played a role in developing the concept of the Blalock Taussig shunt. Pioneers also include patients and their families, and the book includes some discussion of what little is known of childhood and of the child with heart disease in the four different eras. This is a brief overview of the growth of knowledge of children's hearts from before William Harvey until our own time, and includes references to histories of cardiac surgery and to collections of classic cardiac papers. By its emphasis on the child as the central historic figure, and on the interaction of tools and concepts in the growth of knowledge, the text provides a celebratory approach to the 50th anniversary of modern pediatric cardiology.
The twentieth-century journey to understand the human heart was a saga on a par with the race to the moon. Physicians have evolved from fearing to even touch a living human heart to rebuilding and transplanting hearts. Today heart attacks can often be sto
3D Printing Applications in Cardiovascular Medicine addresses the rapidly growing field of additive fabrication within the medical field, in particular, focusing on cardiovascular medicine. To date, 3D printing of hearts and vascular systems has been largely reserved to anatomic reconstruction with no additional functionalities. However, 3D printing allows for functional, physiologic and bio-engineering of products to enhance diagnosis and treatment of cardiovascular disease. This book contains the state-of-the-art technologies and studies that demonstrate the utility of 3D printing for these purposes. Addresses the novel technology and cardiac and vascular application of 3D printing Features case studies and tips for applying 3D technology into clinical practice Includes an accompanying website that provides 3D examples from cardiovascular clinicians, imagers, computer science and engineering experts
Prepare yourself for success with this unique cardiology primer which distils the core information you require and presents it in an easily digestible format. Provides cardiologists with a thorough and up-to-date review of cardiology, from pathophysiology to practical, evidence-based management Ably synthesizes pathophysiology fundamentals and evidence based approaches to prepare a physician for a subspecialty career in cardiology Clinical chapters cover coronary artery disease, heart failure, arrhythmias, valvular disorders, pericardial disorders, and peripheral arterial disease Practical chapters address ECG, coronary angiography, catheterization techniques, ecnocardiography, hemodynamics, and electrophysiological testing Includes over 650 figures, key notes boxes, references for further study, and coverage of clinical trials Review questions at the end of each chapter help clarify topics and can be used for Board preparation - over 375 questions in all!
This edited volume is a definitive text on adaptive clinical trial designs from creation and customization to utilization. As this book covers the full spectrum of topics involved in the adaptive designs arena, it will serve as a valuable reference for researchers working in industry, government and academia. The target audience is anyone involved in the planning and execution of clinical trials, in particular, statisticians, clinicians, pharmacometricians, clinical operation specialists, drug supply managers, and infrastructure providers. In spite of the increased efficiency of adaptive trials in saving costs and time, ultimately getting drugs to patients sooner, their adoption in clinical development is still relatively low. One of the chief reasons is the higher complexity of adaptive design trials as compared to traditional trials. Barriers to the use of clinical trials with adaptive features include the concerns about the integrity of study design and conduct, the risk of regulatory non-acceptance, the need for an advanced infrastructure for complex randomization and clinical supply scenarios, change management for process and behavior modifications, extensive resource requirements for the planning and design of adaptive trials and the potential to relegate key decision makings to outside entities. There have been limited publications that address these practical considerations and recommend best practices and solutions. This book fills this publication gap, providing guidance on practical considerations for adaptive trial design and implementation. The book comprises three parts: Part I focuses on practical considerations from a design perspective, whereas Part II delineates practical considerations related to the implementation of adaptive trials. Putting it all together, Part III presents four illustrative case studies ranging from description and discussion of specific adaptive trial design considerations to the logistic and regulatory issues faced in trial implementation. Bringing together the expertise of leading key opinion leaders from pharmaceutical industry, academia, and regulatory agencies, this book provides a balanced and comprehensive coverage of practical considerations for adaptive trial design and implementation.