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National Bestseller "Gives you all the context you need to understand the science of immunity. ... An Elegant Defense left me with [a] sense of awe.” —Bill Gates, Gates Notes Summer Reading List The Pulitzer Prize–winning New York Times journalist "explicates for the lay reader the intricate biology of our immune system" (Jerome Groopman, MD, New York Review of Books) From New York Times science journalist Matt Richtel, An Elegant Defense is an acclaimed and definitive exploration of the immune system and the secrets of health. Interweaving cutting-edge science with the intimate stories of four individual patients, this epic, first-of-its-kind book “give[s] lay readers a means of understanding what’s known so far about the intricate biology of our immune systems” (The Week). The immune system is our body’s essential defense network, a guardian vigilantly fighting illness, healing wounds, maintaining order and balance, and keeping us alive. It has been honed by evolution over millennia to face an almost infinite array of threats. For all its astonishing complexity, however, the immune system can be easily compromised by fatigue, stress, toxins, advanced age, and poor nutrition—hallmarks of modern life—and even by excessive hygiene. Paradoxically, it is a fragile wonder weapon that can turn on our own bodies with startling results, leading today to epidemic levels of autoimmune disorders. An Elegant Defense effortlessly guides readers on a scientific detective tale winding from the Black Plague to twentieth-century breakthroughs in vaccination and antibiotics, to today’s laboratories that are revolutionizing immunology—perhaps the most extraordinary and consequential medical story of our time. Drawing on extensive new interviews with dozens of world-renowned scientists, Richtel has produced a landmark book, equally an investigation into the deepest riddles of survival and a profoundly human tale that is movingly brought to life through the eyes of his four main characters, each of whom illuminates an essential facet of our “elegant defense.”
"Deserves a spot next to Fast Food Nation and To Kill a Mockingbird in America’s high school curriculums. To say it may save lives is self-evident.” —New York Times Book Review (Editor's Choice) NEW YORK TIMES BESTSELLER • A BEST BOOK OF THE YEAR: San Francisco Chronicle, Chrisitian Science Monitor, Kirkus, Winnipeg Free Press One of the decade's most original and masterfully reported books, A Deadly Wandering by Pulitzer Prize–winning New York Times journalist Matt Richtel interweaves the cutting-edge science of attention with the tensely plotted story of a mysterious car accident and its aftermath to answer some of the defining questions of our time: What is technology doing to us? Can our minds keep up with the pace of change? How can we find balance? On the last day of summer, an ordinary Utah college student named Reggie Shaw fatally struck two rocket scientists while texting and driving along a majestic stretch of highway bordering the Rocky Mountains. A Deadly Wandering follows Reggie from the moment of the tragedy, through the police investigation, the state's groundbreaking prosecution, and ultimately, Reggie's wrenching admission of responsibility. Richtel parallels Reggie's journey with leading-edge scientific findings on the impact technology has on our brains, showing how these devices play to our deepest social instincts. A propulsive read filled with surprising scientific detail, riveting narrative tension, and rare emotional depth, A Deadly Wandering is a book that can change—and save—lives.
This sweeping study examines the law of intellectual property in Chinese civilization from imperial days to the present. It uses materials drawn from law, the arts and other fields as well as extensive interviews with Chinese and foreign officials, business people, lawyers, and perpetrators and victims of "piracy."
Ultimately, Katz argues, the law, as well as our conscience, is surprisingly uninterested in final outcomes and astonishingly sensitive to how we get there, which is why sins of commission are so much more weighty than sins of omission.
"Remarkable. This profound volume informs and inspires." —PW, STARRED review From the Pulitzer Prize–winning New York Times science reporter acclaimed for “bring[ing] scientific concepts to life” (Bill Gates), a pathbreaking new investigation into the mysteries of human creativity How does creativity work? Where does inspiration come from? What are the secrets of our most revered creators? How can we maximize our creative potential? THIS IS THE STORY OF HOW WE CREATE. Creativity defines the human experience. It sparks achievement and innovation in art, science, technology, business, sports, and virtually every activity. It has fueled human progress on a global level, but it equally is the source of profound personal satisfaction for individual creators. And yet the origins of creative inspiration and the methods by which great creators tap into it have long been a source of mystery, spoken of in esoteric terms, our rational understanding shrouded in complex jargon. Until now. Inspired is a book about the science of creativity, distilling an explosion of exciting new research from across the world. Through narrative storytelling, Richtel marries these findings with timeless insight from some of the world’s great creators as he deconstructs the authentic nature of creativity, its biological and evolutionary origins, its deep connection to religion and spirituality, the way it bubbles in each of us, urgent and essential, waiting to be tapped. Many of the questions Richtel addresses are practical: What are the traits of successful creators? Under which conditions does creativity thrive? How can we move past creative blocks? The ultimate message of Inspired is that creativity is more accessible than many might imagine, as necessary, beautiful, and fulfilling as any essential part of human nature.
Integrating theory, research, and applications, this book examines the defense mechanisms and their role in both normal development and psychopathology. It describes how children and adults mobilize specific kinds of defenses to maintain their psychological equilibrium and preserve self-esteem, particularly in situations of trauma or stress.
“MICHAEL CRICHTON meets STEPHEN KING at their finest … with the creepiest opening I’ve ever read.” — Lisa Gardner * “Joins the ranks of classic paranoid thrillers about human achievement run amok, with STEPHEN KING’s The Stand and Michael Crichton’s Terminal Man.” — Joseph Finder * “A heart-stopping thriller. … a must-read for MICHAEL CRICHTON fans.” — Dallas Morning News * “Similar in atmosphere and style to MICHAEL CRICHTON and STEPHEN KING. ... A race-against-the-clock thriller.” — Booklist FLIGHT 194 LANDED. SOMETHING LETHAL AWAITS OUTSIDE. THIS IS DEAD ON ARRIVAL. An airplane touches down at a desolate airport in a remote Colorado ski town. Shortly after landing, Dr. Lyle Martin, a world-class infectious disease specialist, is brusquely awakened to shocking news: Everyone not on the plane appears to be dead. The world has gone dark. While they were in the air, a lethal new kind of virus surfaced, threatening mankind's survival, and now Martin—one of the most sought-after virologists on the planet until his career took a precipitous slide—is at the center of the investigation. Moving at lightning pace from the snowbound Rockies to the secret campus of Google X, where unlimited budgets may be producing wonders beyond our capacity to control, Dead on Arrival is a brilliantly imaginative, intricately plotted thriller that draws on Matt Richtel's years of science and technology reporting for the New York Times, and establishes him as one of the premier thriller writers working today.
This book will teach you how to use word power rather than willpower to increase your motivation and overcome your struggles with eating and body care. It explains how self-talk ties thought to action or inaction and how what we say to ourselves is shaped—for better or worse—by our families, culture and personal history. It illustrates how unconscious, unhealthy self-talk leads to poor decision-making around eating, fitness and general self-care and how conscious, healthy self-talk promotes a positive relationship with food, body and mind. Words to Eat By details key elements of constructive, smart self-talk. You’ll learn how to distinguish trash thoughts from treasure thoughts, why external motivators don’t work long-term, and which internal motivators will fast track you to success. It includes hundreds of examples of exactly what to say and not say to yourself in challenging food situations—eating alone, with family, friends, dates and mates, at parties, restaurants and buffets—and how to get and keep your body moving. Reflective questions help you zero in on which self-talk you want to change, while case studies illustrate how other troubled eaters have transformed their self-talk and their lives. Written by a national expert, award-winning, international author and seasoned clinician who is also half-a-lifetime recovered from weight-loss dieting and binge-eating, this book introduces you to the nitty gritty of your eating and self-care problems and teaches you how to speak to yourself with the love, compassion, encouragement and hope needed to jump start or sustain your recovery.
A stirring defense of liberalism against the dogmatisms of our time from an award-winning and New York Times bestselling author. Not since the early twentieth century has liberalism, and liberals, been under such relentless attack, from both right and left. The crisis of democracy in our era has produced a crisis of faith in liberal institutions and, even worse, in liberal thought. A Thousand Small Sanities is a manifesto rooted in the lives of people who invented and extended the liberal tradition. Taking us from Montaigne to Mill, and from Middlemarch to the civil rights movement, Adam Gopnik argues that liberalism is not a form of centrism, nor simply another word for free markets, nor merely a term denoting a set of rights. It is something far more ambitious: the search for radical change by humane measures. Gopnik shows us why liberalism is one of the great moral adventures in human history -- and why, in an age of autocracy, our lives may depend on its continuation.
The National Book Award finalist and debut novel by the bestselling author of The Dinner Party: "A readymade classic of the office-novel genre. . . . A truly affecting novel about work, trust, love, and loneliness." --Seattle Times No one knows us quite the same way as the men and women who sit beside us in department meetings and crowd the office refrigerator with their labeled yogurts. Every office is a family of sorts, and the ad agency Joshua Ferris brilliantly depicts in his debut novel is family at its strangest and best, coping with a business downturn in the time-honored way: through gossip, pranks, and increasingly frequent coffee breaks. With a demon's eye for the details that make life worth noticing, Joshua Ferris tells a true and funny story about survival in life's strangest environment--the one we pretend is normal five days a week.