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Molecular Genetic Pathology, Second Edition presents up-to-date material containing fundamental information relevant to the clinical practice of molecular genetic pathology. Fully updated in each area and expanded to include identification of new infectious agents (H1N1), new diagnostic biomarkers and biomarkers for targeted cancer therapy. This edition is also expanded to include the many new technologies that have become available in the past few years such as microarray (AmpliChip) and high throughput deep sequencing, which will certainly change the clinical practice of molecular genetic pathology. Part I examines the clinical aspects of molecular biology and technology, genomics. Poharmacogenomics and proteomics, while Part II covers the clinically relevant information of medical genetics, hematology, transfusion medicine, oncology, and forensic pathology. Supplemented with many useful figures and presented in a helpful bullet-point format, Molecular Genetic Pathology, Second Edition provides a unique reference for practicing pathologists, oncologists, internists, and medical genetisists. Furthermore, a book with concise overview of the field and highlights of clinical applications will certainly help those trainees, including pathology residents, genetics residents, molecular pathology fellows, internists, hematology/oncology fellows, and medical technologists in preparing for their board examination/certification.
Provide outstanding healthcare while keeping within budget with this comprehensive, engagingly written guide Understanding Value-Based Healthcare is a succinct, interestingly written primer on the core issues involved in maximizing the efficacy and outcomes of medical care when cost is a factor in the decision-making process. Written by internationally recognized experts on cost- and value-based healthcare, this timely book delivers practical and clinically focused guidance on one of the most debated topics in medicine and medicine administration today. Understanding Value-Based Healthcare is divided into three sections: Section 1 Introduction to Value in Healthcare lays the groundwork for understanding this complex topic. Coverage includes the current state of healthcare costs and waste in the USA, the challenges of understanding healthcare pricing, ethics of cost-conscious care, and more. Section 2 Causes of Waste covers important issues such as variation in resource utilization, the role of technology diffusion, lost opportunities to deliver value, and barriers to providing high-value care. Section 3 Solutions and Tools discusses teaching cost awareness and evidence-based medicine, the role of patients, high-value medication prescribing, screening and prevention, incentives, and implementing value-based initiatives. The authors include valuable case studies within each chapter to demonstrate how the material relates to real-world situations faced by clinicians on a daily basis. .
Equine Clinical Pathology is the first complete resource for hematology and clinical chemistry in horses. Encompassing the basic principles and advanced interpretation, the book’s single-species approach to pathology allows for focused coverage of the unique disease characteristics of equids. Equine Clinical Pathology is equally useful for anyone using clinical pathology as a diagnostic tool, from beginning student to experienced specialist. The heart of the book is organized by body system, making it easy to find and apply information. Chapters cover general laboratory medicine, including instruments and techniques, hematology, and proteins as well as specific organs, such as the kidney and liver. Equine Clinical Pathology is a useful bench-side reference for anyone involved in laboratory medicine for the horse.
Clinical Pathology for the Veterinary Team is a concise, reliable resource for technical team members performing clinical diagnostic evaluation. Focusing on sample handling, machinery calibration, normal physiology and anatomy, clinical diagnostics, and disease processes, this essential bench-side reference for in-house laboratories helps technical team members to consistently achieve high-quality results in small animal lab work. With chapters on blood counts, chemistry, urinalysis and electrolytes, advanced diagnostics, and cytology, Clinical Pathology for the Veterinary Team offers key technical information for consistently obtaining and evaluating samples. The book is a practical resource for anyone performing lab work, including veterinary technicians, technician and veterinary students, and veterinarians.
This book provides in-depth information about common clinical laboratory assays that are used to evaluate domestic mammals, including what assays measure, sample or assay conditions that affect results, and what results indicate about the physiologic or pathologic state of a patient. Whenever possible, diseases and conditions are grouped by common mechanisms or processes to promote a conceptual understanding of laboratory data that can be generally applied across many species. New to the second edition are additional disorders, diagnostic tests, illustrations, images, references, and pathophysiologic explanations. This text has proven valuable to students and veterinarians wanting a fundamental understanding of veterinary clinical pathology.
Written by one of the world's leading haematologists, and three renowned histopathologists, Bone Marrow Pathology provides a comprehensive guide to the diagnosis of bone marrow disease. Now in its Third Edition, the text has been extensively revised and rewritten to reflect the latest advances in the field. Features: An extremely practical, up-to-the-minute text incorporating the new WHO classification of haematopoietic malignancies A comprehensive text written with great precision and clarity of style Incorporates a new section 'Problems and Pitfalls' - a unique section that will aid the working pathologist faced with a difficult situation An important text for the haematologist, histopathologist and haematopathologist with equal weight given to peripheral blood, aspirate, trephine biology and specialized techniques Extensively illustrated with many of the photographs being of paraffin-embedded sections Combines all the techniques now applied to bone marrow diagnosis, including immunocytochemistry, flow cytometery, immunohistochemistry and the diagnostic role of cytogenetic and molecular genetic analysis
Getting the right diagnosis is a key aspect of health care - it provides an explanation of a patient's health problem and informs subsequent health care decisions. The diagnostic process is a complex, collaborative activity that involves clinical reasoning and information gathering to determine a patient's health problem. According to Improving Diagnosis in Health Care, diagnostic errors-inaccurate or delayed diagnoses-persist throughout all settings of care and continue to harm an unacceptable number of patients. It is likely that most people will experience at least one diagnostic error in their lifetime, sometimes with devastating consequences. Diagnostic errors may cause harm to patients by preventing or delaying appropriate treatment, providing unnecessary or harmful treatment, or resulting in psychological or financial repercussions. The committee concluded that improving the diagnostic process is not only possible, but also represents a moral, professional, and public health imperative. Improving Diagnosis in Health Care, a continuation of the landmark Institute of Medicine reports To Err Is Human (2000) and Crossing the Quality Chasm (2001), finds that diagnosis-and, in particular, the occurrence of diagnostic errorsâ€"has been largely unappreciated in efforts to improve the quality and safety of health care. Without a dedicated focus on improving diagnosis, diagnostic errors will likely worsen as the delivery of health care and the diagnostic process continue to increase in complexity. Just as the diagnostic process is a collaborative activity, improving diagnosis will require collaboration and a widespread commitment to change among health care professionals, health care organizations, patients and their families, researchers, and policy makers. The recommendations of Improving Diagnosis in Health Care contribute to the growing momentum for change in this crucial area of health care quality and safety.
Clinical Guide to Fish Medicine Designed as a practical resource, Clinical Guide to Fish Medicine provides an evidence-based approach to the veterinary care of fish. This guide—written and edited by experts in the field—contains essential information on husbandry, diagnostics, and case management of bony and cartilaginous fish. This important resource: Provides clinically relevant information on topics such as anatomy, water quality, life-support systems, nutrition, behavioral training, clinical examination, clinical pathology, diagnostic imaging, necropsy techniques, anesthesia and analgesia, surgery, medical treatment, and transport Describes common presenting problems of fish, including possible differentials and practical approaches Reviews key information on non-infectious and infectious diseases of fish in a concise format that is easily accessible in a clinical setting Written for veterinarians, biologists, technicians, specialists, and students, Clinical Guide to Fish Medicine offers a comprehensive review of veterinary medicine of fish.
The Second Edition of The Milan System for Reporting Salivary Gland Cytopathology, like the First Edition, represents a collaborative effort by a multidisciplinary group of cytopathologists, surgical pathologists, molecular pathologists, radiologists, and head and neck surgeons. This international group shares the goal of creating a practical and uniform reporting system for salivary gland fine needle aspiration (FNA). This book is organized into six general diagnostic categories: “Non-Diagnostic,” “Non-Neoplastic,” “Atypia of Undetermined Significance (AUS),” “Neoplasm: Benign,” “Neoplasm: Salivary Gland Neoplasm of Uncertain Malignant Potential (SUMP),” “Suspicious for Malignancy,” and “Malignant.” It includes definitions, morphologic criteria, and explanations for each of the diagnostic categories. Specific chapters are dedicated to the application of the latest available ancillary studies, radiologic features of salivary gland lesions, clinical management, and histological considerations including updates from the most recent 5th Edition WHO blue book. The Milan System for Reporting Salivary Gland Cytopathology 2nd Edition represents an essential step towards increasing the overall effectiveness of salivary gland FNA and fostering better communication between clinicians and between institutions to improve overall patient care.
An autopsy is a surgical procedure that consists of a thorough examination of a corpse by dissection to determine the cause, mode, and manner of death or to evaluate any disease or injury that may be present for research or educational purposes. This book is a practical guide to autopsy for trainees in pathology and forensic medicine. The second edition has been fully revised to provide the latest advances and guidelines in the field. Beginning with an introduction to autopsy, its utility and techniques for both external and in situ examination, the following chapters explain autopsy procedures for different organ systems of the body, with an emphasis on dissection methods. The final sections explain autopsies in special situations such as in maternal death and in children, autopsy and the law, design of the autopsy room, biosafety, audit, and embalming. The text is further enhanced by photographs of dissection procedures, diagrams and tables. Key points Practical guide to autopsy techniques for trainees in pathology Fully revised, second edition providing latest advances and guidelines Highly illustrated with photographs, diagrams and tables Previous edition (9789386056160) published in 2017