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Pituitary Adenylate Cyclase-Activating Polypeptide is the first volume to be written on the neuropeptide PACAP. It covers all domains of PACAP from molecular and cellular aspects to physiological activities and promises for new therapeutic strategies. Pituitary Adenylate Cyclase-Activating Polypeptide is the twentieth volume published in the Endocrine Updates book series under the Series Editorship of Shlomo Melmed, MD.
Although, as W.D. Billings notes in his chapter in this book. the development of physiological ecology can be traced back to the very beginnings of the study of ecology it is clear that the modern development of this field in North America is due in the large part to the efforts of Billings alone. The foundation that Billings laid in the late 1950s came from his own studies on deserts and subsequently arctic and alpine plants, and also from his enormous success in instilling enthusiasm for the field in the numerous students attracted to the plant ecology program at Duke University. Billings' own studies provided the model for subsequent work in this field. Physiological techniques. normally confined to the laboratory. were brought into the field to examine processes under natural environmental conditions. These field studies were accompanied by experiments under controlled conditions where the relative impact of various factors could be assessed and further where genetic as opposed to environmental influences could be separated. This blending of field and laboratory approaches promoted the design of experiments which were of direct relevance to understanding the distribution and abundance of plants in nature. Physiological mechanisms were studied and assessed in the context of the functioning of plants under natural conditions rather than as an end in itself.
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Following a description of the physical and biological characterization of the four North American deserts together with the primary adaptations of plants to environmental stress, the authors go on to present case studies of key species. They provide an up-to-date and comprehensive review of the major patterns of adaptation in desert plants, with one chapter devoted to several important exotic plants that have invaded these deserts. The whole is rounded off with a synthesis of the resource requirements of desert plants and how they may respond to global climate change.
This short volume contains papers presented at a special symposium, "The Physiology of Aggression and Defeat," during the MAS meetings in Dallas, Texas, in December, 1968. At a time when we need to understand the basic mechan isms underlying various forms of aggression, these papers report progress toward this goal. Although the many social, psychologic and economic causal mechanisms contributing to aggression have been reasonably well-understood for a number of years, the correlated physiological, biochemical, endocrinological and neurochemical changes taking place in an organism that is either the aggressor or the recipient of aggression have not been studied extensively, and the limited available data in the past have often been in con siderable conflict. These eight papers demonstrate that complex interac tions take place among the psychological, social, physio logical, biochemical, endocrinological and neurochemical factors involved in aggression and defeat. The general indications are that while the aggressor learns to survive and adapts readily to the fighting process, the vanquished, if he does not die, maintains an existence highlighted by severe and extensive changes in all physiologic and psycho logic systems. We cannot make sweeping generalizations to the human organism from the results of non-human animal experimentation. Nevertheless, it is well-known that in all animals, including the human, similar basic biochemi cal systems are involved.
The concept of homeostasis, the maintenance of the internal physiological environment of an organism within tolerable limits, is well established in medicine and physiology. In contrast, allostasis is a relatively new idea of 'viability through change'. With allostatic regulation by cephalic involvement, the body adapts to potentially diverse and dangerous situations through the activation of neural, hormonal, or immunological mechanisms. Allostasis explains how regulatory events maintain organismic viability, or not, in diverse contexts with varying set points of bodily needs and competing motivations. This 2005 book introduces the concept of allostasis and sets it alongside traditional views of homeostasis. It addresses basic regulatory systems and examines the behavior of bodily regulation under duress. The basic concepts of physiological homeostasis are integrated with disorders like depression, stress, anxiety and addiction. It will therefore appeal to graduate students, medical students and researchers working in physiology, epidemiology, endocrinology, neuroendocrinology, neuroscience, and psychology.
This book offers physiology teachers a new approach to teaching their subject that will lead to increased student understanding and retention of the most important ideas. By integrating the core concepts of physiology into individual courses and across the entire curriculum, it provides students with tools that will help them learn more easily and fully understand the physiology content they are asked to learn. The authors present examples of how the core concepts can be used to teach individual topics, design learning resources, assess student understanding, and structure a physiology curriculum.
In the United States, some populations suffer from far greater disparities in health than others. Those disparities are caused not only by fundamental differences in health status across segments of the population, but also because of inequities in factors that impact health status, so-called determinants of health. Only part of an individual's health status depends on his or her behavior and choice; community-wide problems like poverty, unemployment, poor education, inadequate housing, poor public transportation, interpersonal violence, and decaying neighborhoods also contribute to health inequities, as well as the historic and ongoing interplay of structures, policies, and norms that shape lives. When these factors are not optimal in a community, it does not mean they are intractable: such inequities can be mitigated by social policies that can shape health in powerful ways. Communities in Action: Pathways to Health Equity seeks to delineate the causes of and the solutions to health inequities in the United States. This report focuses on what communities can do to promote health equity, what actions are needed by the many and varied stakeholders that are part of communities or support them, as well as the root causes and structural barriers that need to be overcome.