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Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. - Includes the authority and expertise of leading contributors in pharmacology - Presents the latest release in the Advances in Pharmacology series
Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.
Analyzing how tennis turned pro The arrival of the Open era in 1968 was a watershed in the history of tennis--the year that marked its advent as a professionalized sport. Merging wide-angle history with individual stories of players and off-the-court figures, Greg Ruth charts tennis’s evolution into the game we watch today. His vivid account moves from the cloistered world of nineteenth-century lawn tennis through the longtime amateur-professional divide and the battles over commercialization that raged from the 1920s until 1968. From there, Ruth details the post-1968 expansion of the game as it was transformed by bankable superstars, a popular women’s tour, rival governing bodies, and sponsorship money. What emerges is a fascinating history of the economics and politics that made tennis a decisive, if unlikely, force in the creation of modern-day sports entertainment. Comprehensive and engaging, Tennis tells the interlocking stories of the figures and factors that birthed the professional game.