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In this issue of Clinics in Liver Disease, Guest Editor Paul Kwo brings his considerable expertise to the topic of Alcoholic Hepatitis. Top experts in the field cover key topics such as the Epidemiology of Alcoholic Hepatitis, Nutrition in Those with Alcoholic Hepatitis, Current therapies for alcoholic hepatitis, Selection Criteria for Liver Transplantation for Acute Alcoholic Hepatitis, and more. - Provides in-depth, clinical reviews on Alcoholic Hepatitis, providing actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews. - Contains 11 relevant, practice-oriented topics including Emerging Therapies for alcoholic hepatitis; Diagnosis of Alcoholic Hepatitis; Moderate Alcoholic Hepatitis; Current and Future Biomarkers in Alcoholic Hepatitis, and more.
With collaboration from Consulting Editor, Dr. Norman Gitlin Dr. Goldberg has assembled a state-of-the-art issue devoted to management of liver transplant patients. Expert authors have contributed current clinical reviews that covers the breadth of the pre- and post-surgical journey. Articles are specifically devoted to the following topics: Obesity management of liver transplant waitlist candidates and recipients; Expanding the limits of liver transplantation for hepatocellular carcinoma: Is there a limit; Frailty and sarcopenia in patients pre- and post-liver transplant; Achieving tolerance in liver transplantation: Where are we now and what does the future hold; Expanding role of donation after cardiac death donors; Optimizing selection of patients for simultaneous liver-kidney transplant; Keeping the patient with end-stage liver disease alive while awaiting transplant: Management of complications of portal hypertension; Expanding donor selection and recipient indications for living donor liver transplantation; The changing liver transplant recipient: From hepatitis C to NASH and alcohol; Cardiovascular risk stratification in liver transplant candidates; The role of machine perfusion in liver transplantation: Warm, Cold, or does it not matter; Paradigm shift in utilization of livers from hepatitis C-viremic donors into HCV-negative patients; Transplantation of elderly patients: Is there an upper age cutoff; Transplantation for acute alcoholic hepatitis: Controversies and early successes. Hepatologists will come away with the information they need to improve outcomes in liver transplant patients.
This volume presents a concise yet comprehensive overview on all facets concerning the complications of cirrhosis. Structured in three sections, the book reviews the natural history of cirrhosis, the diagnostic and predictive tools available to assess the disease, complications, and treatment options such as liver assist devices and transplantation. Topical concerns in the management of patients with cirrhosis are also addressed, including issues pertaining to the delivery of quality care in this patient population. Written by experts in their fields, Complications of Cirrhosis: Evaluation and Management serves as a valuable resource for practitioners and physicians-in-training on the subject of cirrhosis.
Chronic liver failure is a frequent condition in clinical practice that encompasses all manifestations of patients with end-stage liver diseases. Chronic liver failure is a multiorgan syndrome that affects the liver, kidneys, brain, heart, lungs, adrenal glands, and vascular, coagulation, and immune systems. Chronic Liver Failure: Mechanisms and Management covers for the first time all aspects of chronic liver failure in a single book, from pathogenesis to current management. Each chapter is written by a worldwide known expert in their area and all provide the latest state-of-the-art knowledge. This volume is specifically designed to provide answers to clinical questions to all doctors dealing with patients with liver diseases, not only clinical gastroenterologists and hepatologists, but also to internists, nephrologists, intensive care physicians, and transplant surgeons.
In collaboration with Consulting Editor, Dr. Norman Gitlin, Guest Editors Drs. Andres Cardenas and Thomas Reiberger have created an up-to-date monograph on the complications of cirrhosis. They have secured top experts to contribute clinical review articles on the following topics: Non-invasive Detection of CSPH in cACLD; Prevention of First Decompensation in ACLD; Treatment of Acute Variceal Bleeding in 2020: When to Use TIPS; Prevention of Variceal Bleeding and Rebleeding by NSBB: A Tailored Approach; The Role of Hepatic Venous Pressure Gradient (HVPG); Measurement in the Management of Cirrhosis; Bacterial Infections in Cirrhosis as a Cause or Consequence of Decompensation; Nutrition in Chronic Liver Disease; Diagnosis and Management of Hepatic Encephalopathy; Discriminating Acute Decompensation from Acute-on-Chronic Liver; Management of Severe and Refractory Ascites; Monitoring Renal Function and Therapy of HRS patients with Cirrhosis; Coagulopathy in Cirrhosis; and Current Concepts of Cirrhotic Cardiomyopathy. Hepatologists will come away with the information they need to manage these patients.
In this issue of Clinics in Liver Disease, guest editor Dr. Steven L. Flamm brings his considerable expertise to the topic of Updates in Consultations in Liver Disease. Many disease entities are uncommon and complicated in scope, and liver disease may occur in the setting of other chronic medical conditions and involve other organ systems. In this issue, top experts provide a up-to-date framework for approaching consultation for common liver-related problems for the gastroenterology and hepatology practitioner. - Contains 12 practice-oriented topics including clinical pearls in evaluation and treatment of patients with liver disease; evaluation of patients with markedly elevated liver enzymes; evaluation of liver disease in pregnancy; COVID and implications on the liver; and more. - Provides in-depth clinical reviews on consultations in liver disease, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
In this issue of Clinics in Liver Disease, guest editor Dr. Ashwani K. Singal brings his considerable expertise to the topic of Alcohol-Associated Liver Disease. Portal hypertension is often one of the major complications seen in advanced liver disease. Top experts discuss various aspects of alcohol-associated liver disease (ALD), to provide comprehensive coverage on current status, update recent developments especially during the last decade, and highlight clinical and experimental unmet needs for practicing providers and for researchers in the field of ALD. - Contains 18 relevant, practice-oriented topics including microbiome in ALD; diagnosis of alcoholic use disorder and of ALD; non-invasive tests in assessment of ALD patients; treatment of alcoholic use disorder: behavioral and pharmacological therapies; current medical treatment of ALD: pharmacological and nutrition; liver transplantation in ALD; digital technology and AI in management of ALD; and more. - Provides in-depth clinical reviews on alcohol-associated liver disease, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
In collaboration with Consulting Editor, Dr. Norman Gitlin, Dr. Pierre Gholam has put together topics that provide a current clinical update on the treatment and management of patients with drug-induced liver injury (DILI). Expert authors have contributed clinical review articles on the following topics: Epidemiology, Predisposing Factors and Outcomes; Genetic Predisposition to DILI; Causality Assessment Frequent Offenders and Patterns of Injury; Quantitative Systems Toxicology Approaches to Understand and Predict DILI; Liver Histology: Diagnostic and Prognostic Features; Acute Liver Failure Secondary to DILI; DILI in Persons with Pre-existing Chronic Liver Disease; DILI in the Setting of Statin Use; DILI in the Setting of Analgesic Use; DILI Secondary to Herbals and Dietary Supplements; and DILI Reporting and Resources for the Clinician. Readers will come away with the information they need to improve outcomes in patients with DILI.
Variceal Hemorrhage provides an update of the evidence concerning several aspects of variceal hemorrhage. The book features new information on natural history, diagnosis of esophageal varices, assessment of the risk of bleeding and identification of high risk groups and patients who may benefit or be harmed from different treatments. The volume also presents a critical analysis of the different steps in the management of acute variceal bleeding. Authored by the most prominent world experts in their areas of expertise, Variceal Hemorrhage serves as a very useful reference for gastroenterologists, GI surgeons, residents in internal medicine and physicians dealing with and interested in the different aspects of this severe medical emergency.
In this issue of Clinics in Liver Disease, guest editor Dr. Nikolaos T. Pyrsopoulos brings his considerable expertise to the topic of Acute-on-Chronic Liver Failure. Recent studies indicate that as many as one in four patients with cirrhosis develop acute-on-chronic liver failure (ACLF) and 25% die within one month. This issue, the first devoted to this topic, provides thorough coverage of critical clinical interventions, including diagnosis, treatment, and management. It also focuses on early recognition of ACLF, which is important for the initiation of aggressive management and ultimately, saving lives. - Contains 17 practice-oriented topics including ACLF: mechanisms of disease and multisystemic involvement; the clinical spectrum and manifestations of ACLF; management of ACLF; maximizing the donor potential for patients with ACLF Listed for Liver Transplant; future approaches and therapeutic modalities for ACLF; and more. - Provides in-depth clinical reviews of acute-on-chronic liver failure, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.