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This is a pioneering textbook on the comprehensive description of AeroMACS technology. It also presents the process of developing a new technology based on an established standard, in this case IEEE802.16 standards suite. The text introduces readers to the field of airport surface communications systems and provides them with comprehensive coverage of one the key components of the Next Generation Air Transportation System (NextGen); i.e., AeroMACS. It begins with a critical review of the legacy aeronautical communications system and a discussion of the impetus behind its replacement with network-centric digital technologies. It then describes wireless mobile channel characteristics in general, and focuses on the airport surface channel over the 5GHz band. This is followed by an extensive coverage of major features of IEEE 802.16-2009 Physical Layer (PHY)and Medium Access Control (MAC) Sublayer. The text then provides a comprehensive coverage of the AeroMACS standardization process, from technology selection to network deployment. AeroMACS is then explored as a short-range high-data-throughput broadband wireless communications system, with concentration on the AeroMACS PHY layer and MAC sublayer main features, followed by making a strong case in favor of the IEEE 802.16j Amendment as the foundational standard for AeroMACS networks. AeroMACS: An IEEE 802.16 Standard-Based Technology for the Next Generation of Air Transportation Systems covers topics such as Orthogonal Frequency Division Multiple Access (OFDMA), coded OFDMA, scalable OFDMA, Adaptive Modulation-Coding (AMC), Multiple-Input Multiple-Output (MIMO) systems, Error Control Coding (ECC) and Automatic Repeat Request (ARQ) techniques, Time Division Duplexing (TDD), Inter-Application Interference (IAI), and so on. It also looks at future trends and developments of AeroMACS networks as they are deployed across the world, focusing on concepts that may be applied to improve the future capacity. In addition, this text: Discusses the challenges posed by complexities of airport radio channels as well as those pertaining to broadband transmissions Examines physical layer (PHY) and Media Access Control (MAC) sublayer protocols and signal processing techniques of AeroMACS inherited from IEEE 802.16 standard and WiMAX networks Compares AeroMACS and how it relates to IEEE 802.16 Standard-Based WiMAX AeroMACS: An IEEE 802.16 Standard-Based Technology for the Next Generation of Air Transportation Systems will appeal to engineers and technical professionals involved in the research and development of AeroMACS, technical staffers of government agencies in aviation sectors, and graduate students interested in standard-based wireless networking analysis, design, and development.
The first edition of Comprehensive Medicinal Chemistry was published in 1990 and was very well received. Comprehensive Medicinal Chemistry II is much more than a simple updating of the contents of the first edition. Completely revised and expanded, this new edition has been refocused to reflect the significant developments and changes over the past decade in genomics, proteomics, bioinformatics, combinatorial chemistry, high-throughput screening and pharmacology, and more. The content comprises the most up-to-date, authoritative and comprehensive reference text on contemporary medicinal chemistry and drug research, covering major therapeutic classes and targets, research strategy and organisation, high-throughput technologies, computer-assisted design, ADME and selected case histories. It is this coverage of the strategy, technologies, principles and applications of medicinal chemistry in a single work that will make Comprehensive Medicinal Chemistry II a unique work of reference and a single point of entry to the literature for pharmaceutical and biotechnology scientists of all disciplines and for many industry executives as well. Also available online via ScienceDirect (2006) - featuring extensive browsing, searching, and internal cross-referencing between articles in the work, plus dynamic linking to journal articles and abstract databases, making navigation flexible and easy. For more information, pricing options and availability visit www.info.sciencedirect.com. Comprehensively reviews - the strategies, technologies, principles and applications of modern medicinal chemistry Provides a global and current perspective of today's drug discovery process and discusses the major therapeutic classes and targets Includes a unique collection of case studies and personal assays reviewing the discovery and development of key drugs