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This book offers a structured overview and a comprehensive guide to the emerging field of Autonomous Intelligent Cyber Defense Agents (AICA). The book discusses the current technical issues in autonomous cyber defense and offers information on practical design approaches. The material is presented in a way that is accessible to non-specialists, with tutorial information provided in the initial chapters and as needed throughout the book. The reader is provided with clear and comprehensive background and reference material for each aspect of AICA. Today’s cyber defense tools are mostly watchers. They are not active doers. They do little to plan and execute responses to attacks, and they don’t plan and execute recovery activities. Response and recovery – core elements of cyber resilience – are left to human cyber analysts, incident responders and system administrators. This is about to change. The authors advocate this vision, provide detailed guide to how such a vision can be realized in practice, and its current state of the art. This book also covers key topics relevant to the field, including functional requirements and alternative architectures of AICA, how it perceives and understands threats and the overall situation, how it plans and executes response and recovery, how it survives threats, and how human operators deploy and control AICA. Additionally, this book covers issues of testing, risk, and policy pertinent to AICA, and provides a roadmap towards future R&D in this field. This book targets researchers and advanced students in the field of cyber defense and resilience. Professionals working in this field as well as developers of practical products for cyber autonomy will also want to purchase this book.
Fully revised and updated, the Handbook serves as a practical guide to endovascular methods and as a concise reference for neurovascular anatomy and published data about cerebrovascular disease from a neurointerventionalist’s perspective. Divided into three parts, the book covers: Fundamentals of neurovascular anatomy and basic angiographic techniques; Interventional Techniques and endovascular methods, along with useful device information and tips and tricks for daily practice; Specific Disease States, with essential clinical information about commonly encountered conditions. New features in the 2nd Edition include: Global Gems that illuminate aspects of the field outside the United States; Angio-anatomic and angio-pathologic image correlates; Newly released clinical study results influencing neurointerventional practice; Information on emerging technologies in this rapidly advancing field. The Handbook is a vital resource for all clinicians involved in neurointerventional practice, including radiologists, neurosurgeons, neurologists, cardiologists, and vascular surgeons.
We are now entering the third decade of the 21st Century, and, especially in the last years, the achievements made by scientists have been exceptional, leading to major advancements in the fast-growing field of Adolescent and Young Adult Psychiatry. Frontiers has organized a series of Research Topics to highlight the latest advancements in research across the field of Adolescent and Young Adult Psychiatry, with articles from the Associate Members of our accomplished Editorial Boards. This editorial initiative of particular relevance, led by Professor Cohen, Specialty Chief Editor of the Adolescent and Young Adult Psychiatry section, is focused on new insights, novel developments, current challenges, latest discoveries, recent advances, and future perspectives in the field of Adolescent and Young Adult Psychiatry
Considerable impetus was given to the study and understanding of cere brovascular anatomy by Thomas Willis and his contemporaries in the seventeenth century, yet almost two hundred years were to pass before further significant advances were made in this field. Then, from the mid nineteenth century onwards, the dark ages of cerebrovascular research gradually lifted through the efforts of such workers as Luschka, Heubner, and Windle, whose pioneering anatomical studies formed the basis of the present-day understanding of the morphology of the cerebral circulation. The turn of the century saw an increasing influence of the early neurolo gists in describing anatomy of cerebral vessels in relation to their areas of distribution and to the production of focal deficits through specific vascu lar lesions and anomalies. Later still, Padget and others made important observations concerning phylogenetic and developmental aspects of the cerebral circulation. These anatomical and clinical studies were remarkable enough but the real breakthrough in investigating cerebral pathophysiology and in devis ing appropriate corrective neurosurgical procedures had to await the re markable advances in technology of the past fifty years. These began with the advent of cerebral angiography with all its subsequent refinements and progress has been accelerated through establishing noninvasive Doppler and high resolution ultrasound imaging techniques, methods for the accu rate measurement of cerebral blood flow, CT scanning, PET scanning, and, most recently, imaging and metabolic NMR scanning.
Continued Praise for Clinical Neurophysiology of the Vestibular System.
This book provides a framework for understanding the pathophysiology of diseases involving the vestibular system. The book is divided into four parts: I. Anatomy and physiology of the vestibular system; II. Evaluation of the dizzy patient; III. Diagnosis and management of common neurotologic disorders; and IV. Symptomatic treatment of vertigo. Part I reviews the anatomy and physiology of the vestibular system with emphasis on clinically relevant material. Part II outlines the important features in the patient's history, examination, and laboratory evaluation that determine the probable site of lesion. Part III covers the differential diagnostic points that help the clinician decide on the cause and treatment of the patient's problem. Part IV describes the commonly used antivertiginous and antiemetic drugs and the rationale for vestibular exercises. The recent breakthroughs in the vestibular sciences are reviewed. This book will helpful to all physicians who study and treat patients complaining of dizziness.
Chromatographic & Electrophoretic Techniques, Fourth Edition, Volume I: Paper and Thin Layer Chromatography presents the methods of paper and thin layer chromatography. This book discusses the practical approach in the application of paper and thin layer chromatography techniques in the biological sciences. Organized into 18 chapters, this edition begins with an overview of the clinical aspects related to the detection of those metabolic diseases that can result in serious illness presenting in infancy and early childhood. This text then discusses the three major types of screening for inherited metabolic disorders in which paper or thin-layer chromatography are being used, including screening the healthy newborn population, screening the sick hospitalized child, and screening mentally retarded patients. Other chapters consider the procedures for thin layer chromatography. This book discusses as well the complexity of amino acid mixtures present in natural products. The final chapter deals with the detection of synthetic basic drugs. This book is a valuable resource for chemists and toxicologists.
The first comprehensive text on the cerebellum and its disorders for many years.
Now in a fully revised and expanded second edition, this book remains the gold standard guide to the surgical treatment of diseases in the cerebellopontine angle (CPA), the fragile area of the skull base that Harvey Cushing famously described as “the bloody angle.” This edition combines current information on the relevant clinical diseases of the CPA with dramatically improved surgical management of its diseases, arranged in five thematic sections. The first section presents the basis and rationale for treatment, including historical perspectives, microsurgical anatomy, relevant radiology and neurology. Part two is composed of chapters on surgical approaches, and parts three and four provide detailed descriptions of surgical management techniques for vestibular schwannomas and non schwannomatous lesions, respectively. The final section provides 21 distinct clinical cases with associated video segments, demonstrating the approaches and techniques in real time. With images courtesy of the renowned Barrow Neurological Institute, Surgery of the Cerebellopontine Angle, Second Edition is a boon resource for expert specialists in neurosurgery, neurotology, neuroradiology, otolaryngology/head and neck surgery, and endovascular surgery.