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Wound healing and wound care technologies are an ever expanding field with the advancement of materials science, biomedicine and tissue engineering. In the year 2011 the global wound care market generated US$ 6,500 million with an annual growth rate of 7.5%. The global advanced wound care products market share in 2023 is predicted to be approximately US$ 16,300 million.This book discusses the evolution of wound care devices and protocol over the years and different technologies being used in the present day wound care treatment. New strategies involving engineered tissues and drug delivery to mimic the natural wound healing milieu are discussed. The use of cytokine growth factors enhances chronic wound healing particularly for burn wound healing. Prevention of scarring, keloid formation or contractures and a cosmetically acceptable healing is a challenge even now.Skin tissue engineering was the first successfully clinically applied product in regenerative medicine. Bioengineered skin seeded with fibroblast and keratinocyte cells could form a permanent solution that do not require skin grafting or as a temporary cover for burns prior to grafting. Cell attachment, proliferation and tissue formation in a three-dimensional porous scaffold can be engineered for specific application. These cell based skin substitutes had significant wound healing and scar reducing effect on patients.Gene-activated dermal equivalent is another emerging approach for the healing of full thickness incision wounds with good remodelling of the skin. The book also describes similar latest developments on wound healing science and research.The target audiences are wound care professionals, researchers working on wound healing technology and skin tissue engineering; as well as graduate students and industries that need to understand the aspects of wound healing and technological orientation towards successful commercialisation.
The latest research on techniques for effective healing of chronic and difficult to heal wounds The healing of chronic wounds is a global medical concern, specifically for patients suffering from obesity and type II diabetes. Therapeutic Dressing and Wound Healing Applications is an essential text for research labs, industry professionals, and general clinical practitioners that want to make the shift towards advanced therapeutic dressing and groundbreaking wound application for better healing. This book takes a clinical and scientific approach to wound healing, and includes recent case studies to highlight key points and areas of improvement. It is divided into two key sections that include insight into the biochemical basis of wounds, as well as techniques and recent advancements. Chapters include information on: ● Debridement and disinfection properties of wound dressing ● Biofilms, silver nanoparticles, and honey dressings ● Clinical perspectives for treating diabetic wounds ● Treating mixed infections ● Wound healing and tissue regeneration treatments ● Gene based therapy, 3D bioprinting and freeze-dried wafers Anyone looking to update and improve the treatment of chronic wounds for patients will find the latest pertinent information in Therapeutic Dressing and Wound Healing Applications.
Innovations and Emerging Technologies in Wound Care is a pivotal book on the prevention and management of chronic and non-healing wounds. The book clearly presents the research and evidence that should be considered when planning care interventions to improve health related outcomes for patients. New and emerging technologies are discussed and identified, along with tactics on how they can be integrated into clinical practice. This book offers readers a bridge between biomedical engineering and medicine, with an emphasis on technological innovations. It includes contributions from engineers, scientists, clinicians and industry professionals. Users will find this resource to be a complete picture of the latest knowledge on the tolerance of human tissues to sustained mechanical and thermal loads that also provides a deeper understanding of the risk for onset and development of chronic wounds. Describes the state-of-knowledge in wound research, including tissue damage cascades and healing processes Covers all state-of-the-art technology in wound prevention, diagnosis, prognosis and treatment Discusses emerging research directions and future technology trends in the field of wound prevention and care Offers a bench-to-bedside exploration of the key issues that affect the practice of prevention and management of non-healing wounds
The skin is the largest human organ system. Loss of skin integrity due to injury or illness results in a substantial physiologic imbalance and ultimately in severe disability or death. From burn victims to surgical scars and plastic surgery, the therapies resulting from skin tissue engineering and regenerative medicine are important to a broad spectrum of patients. Skin Tissue Engineering and Regenerative Medicine provides a translational link for biomedical researchers across fields to understand the inter-disciplinary approaches which expanded available therapies for patients and additional research collaboration. This work expands on the primary literature on the state of the art of cell therapies and biomaterials to review the most widely used surgical therapies for the specific clinical scenarios. - Explores cellular and molecular processes of wound healing, scar formation, and dermal repair - Includes examples of animal models for wound healing and translation to the clinical world - Presents the current state of, and clinical opportunities for, extracellular matrices, natural biomaterials, synthetic biomaterials, biologic skin substitutes, and adult and fetal stem and skin cells for skin regenerative therapies and wound management - Discusses new innovative approaches for wound healing including skin bioprinting and directed cellular therapies
An important and growing area of the textile industry is the medical sector. The extent of this growth is due to constant improvements in both textile technology and medical procedures. This collection provides a detailed review of how textiles are incorporated into wound care applications, explaining the importance and suitability of using textiles on different wound types.Part one of the book provides an overview of the use of textiles in particular aspects of wound care, providing details of wound management and the importance of laboratory testing in relation to wound care. Further chapters cover minor wounds, moist wound management and bioactive dressings to promote healing. Given their increasing importance, part two describes how advanced textiles, such as smart temperature controlled textiles and composites, can be used for wound care products. The final chapter gives an interesting insight into the use of fibrous scaffolds for tissue engineering.Advanced textiles for wound care is essential reading for any manufacturers, designers, scientists and producers of wound care materials. It is a valuable resource for professionals within the medical sector, as well as those in academia. - Provides a comprehensive introduction to wound care from types of wound and wound healing mechanisms to the importance of testing in relation to wound care - Analyses the application of textiles to wound healing covering minor wounds, burns, ulcers and other deep skin wounds - Reviews the current use of smart textiles for wound care including drug delivery dressings and textile-based scaffolds for tissue engineering as well as future trends
Choose the best possible skin and wound care products to support your patients’ skin health and wound healing, with the invaluable Product Guide to Skin and Wound Care, 8th Edition. Listing 294 products in alphabetical order, this handy product guide for wound care practitioners across all practice settings offers detailed information—sizes, action, indications, contraindications, application, and removal information—so that your choices stay informed and accurate.
Natural Polymers in Wound Healing and Repair: From Basic Concepts to Emerging Trends presents comprehensive coverage on the development and application of natural polymers in wound healing and repair, including fundamental concepts, traditional approaches, cutting-edge methods and emerging trends. The application of natural polymers has evolved from their use in the simplest wound management material, to drug eluting matrices, to cell-laden constructs, and to 3D bio-printed skin equivalents. This book reflects the remarkable progress that has been made in recent years in this innovative field. This is an essential resource for researchers, scientists, and advanced students across polymer science, biomaterials, bio-based and sustainable materials, biomedicine, biomedical engineering, pharmaceuticals, and materials science and engineering. It will also be valuable to R&D professionals, scientists, technologists and all those working in a medical setting who are interested in the latest developments in advanced materials for wound management, healing and repair. - Provides up-to-date coverage of natural polymer-based biomaterials in wound healing and repair, covering sources, processing and properties - Describes cellular and molecular events in wound healing - Introduces conventional and advanced methodologies for wound management - Offers a comprehensive understanding of state-of-the-art and emerging concepts in wound healing, including drug-eluting matrices, cell-laden systems and personalized bio-fabrication strategies
Wound repair is an important and growing sector of the medical industry with increasingly sophisticated biomaterials and strategies being developed to treat wounds. Advanced wound repair therapies provides readers with up-to-date information on current and emerging biomaterials and advanced therapies concerned with healing surgical and chronic wounds.Part one provides an introduction to chronic wounds, with chapters covering dysfunctional wound healing, scarring and scarless wound healing and monitoring of wounds. Part two covers biomaterial therapies for chronic wounds, including chapters on functional requirements of wound repair biomaterials, polymeric materials for wound dressings and interfacial phenomena in wound healing. In part three, molecular therapies for chronic wounds are discussed, with chapters on topics such as drug delivery, molecular and gene therapies and antimicrobial dressings. Part four focuses on biologically-derived and cell-based therapies for chronic wounds, including engineered tissues, biologically-derived scaffolds and stem cell therapies for wound repair. Finally, part five covers physical stimulation therapies for chronic wounds, including electrical stimulation, negative pressure therapy and mechanical debriding devices.With its distinguished editor and international team of contributors, Advanced wound repair therapies is an essential reference for researchers and materials scientists in the wound repair industry, as well as clinicians and those with an academic research interest in the subject. - Provides readers with up-to-date information on current and emerging biomaterials and advanced therapies concerned with healing surgical and chronic wounds - Chapters include the role of micro-organisms and biofilms in dysfunctional wound healing, tissue-biomaterial interaction and electrical stimulation for wound healing - Covers biologically-derived and cell-based therapies for chronic wounds, including engineered tissues, biologically-derived scaffolds and stem cell therapies for wound repair
Hydrogels Based on Natural Polymers presents the latest research on natural polymer-based hydrogels, covering fundamentals, preparation methods, synthetic pathways, advanced properties, major application areas, and novel characterization techniques. The advantages and disadvantages of each natural polymer-based hydrogel are also discussed, enabling preparation tactics for specific properties and applications. Sections cover fundamentals, development, characteristics, structures and properties. Additional chapters cover presentation methods and properties based on natural polymers, including physical and chemical properties, stimuli-responsive properties, self-healing properties, and biological properties. The final section presents major applications areas, including the biomedical field, agriculture, water treatments, and the food industry. This is a highly valuable resource for academic researchers, scientists and advanced students working with hydrogels and natural polymers, as well as across the fields of polymer science, polymer chemistry, plastics engineering, biopolymers and biomaterials. The detailed information will also be of great interest to scientists and R&D professionals, product designers, technicians and engineers across industries. Provides systematic coverage of all aspects of hydrogels based on natural polymers, including fundamentals, preparation methods, properties and characterization Offers a balanced assessment of the specific properties and possibilities offered by different natural polymer-based hydrogels, drawing on innovative research Examines cutting-edge applications across biomedicine, agriculture, water treatments, and the food industry