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This book concisely reviews important advances in radiation oncology, providing practicing radiation oncologists with a fundamental understanding of each topic and an appreciation of its significance for the future of radiation oncology. It explores in detail the impact of newer imaging modalities, such as multiparametric magnetic resonance imaging (MRI) and positron emission tomography (PET) using fluorodeoxyglucose (FDG) and other novel agents, which deliver improved visualization of the physiologic and phenotypic features of a given cancer, helping oncologists to provide more targeted radiotherapy and assess the response. Due consideration is also given to how advanced technologies for radiation therapy delivery have created new treatment options for patients with localized and metastatic disease, highlighting the increasingly important role of image-guided radiotherapy in treating systemic and oligometastatic disease. Further topics include the potential value of radiotherapy in enhancing immunotherapy thanks to the broader immune-stimulatory effects, how cancer stem cells and the tumor microenvironment influence response, and the application of mathematical and systems biology methods to radiotherapy.
Radiation Technology for Advanced Materials presents a range of radiation technology applications for advanced materials. The book aims to bridge the gap between researchers and industry, describing current uses and future prospects. It describes the mature radiation processing technology used in preparing heat shrinkable materials and in wire and cable materials, giving commercial cases. In addition, the book illustrates future applications, including high-performance fibers, special self-lubricating materials, special ultra-fine powder materials, civil fibers, natural polymeric materials, battery separator membranes, special filtration materials and metallic nanomaterials. Chapters cover radiation technology in high-performance fiber and functional textiles, radiation crosslinking and typical applications, radiation crosslinking for polymer foaming material, radiation degradation and application, radiation emulsion polymerization, radiation effects of ionic liquids, radiation technology in advanced new materials, and future prospects. - Presents a range of radiation technology applications and their application to advanced materials - Covers the mature radiation processing technology used to prepare heat shrinkable materials and wire cable materials, describing real-world commercial applications - Shows the promising application of radiation technology in preparing high-performance Si and carbon fibers - Describes the radiation degradation/radiation effect used to prepare fine powder materials - Discusses radiation modification and radiation grafting techniques used to synthesize materials, such as civil fibers, natural polymeric materials and others
This book, now in its second edition, provides a comprehensive overview of current re-irradiation strategies, with detailed discussion of re-irradiation methods, technical aspects, the role of combined therapy with anticancer drugs and hyperthermia, and normal tissue tolerance. In addition, disease specific chapters document recent clinical results and future research directions. All chapters from the first edition have been revised and updated to take account of the latest developments and research findings, including those from prospective studies. Due attention is paid to the exciting developments in the fields of proton irradiation and frameless image-guided ablative radiotherapy. The book documents fully how refined combined modality approaches and significant technical advances in radiation treatment planning and delivery have facilitated the re-irradiation of previously exposed volumes, allowing both palliative and curative approaches to be pursued at various disease sites. Professionals involved in radiation treatment planning and multimodal oncology treatment will find it to be an invaluable aid in understanding the benefits and limitations of re-irradiation and in designing prospective trials.
Developments in radiation oncology have been key to the tremendous progress made in the field in recent years. The combination of optimal systemic treatment and local therapy has resulted in continuing improved outcomes of cancer therapy. This progress forms the basis for current pre-clinical and clinical research which will strengthen the position of radiation oncology as an essential component of oncological care. This book summarizes recent advances in radiotherapy research and clinical patient care. Topics include radiobiology, radiotherapy technology, and particle therapy. Chapters cover a summary and analysis of recent developments in the search for biomarkers for precision radiotherapy, novel imaging possibilities and treatment planning, and advances in understanding the differences between photon and particle radiotherapy. Advances in Radiation Therapy is an invaluable source of information for scientists and clinicians working in the field of radiation oncology. It is also a relevant resource for those interested in the broad topic of radiotherapy in general.
"The IAEA officer responsible for this publication was M. Haji-Saeid"--Foreword.
This text examines the effect of radiation on polymers and the versatility of its industrial applications. By helping readers understand and solve problems associated with radiation processing of polymers, it serves as an important reference and fills a gap in the literature. Radiation processing can significantly improve important properties of polymers, however, there are still misconceptions about processing polymers by using ionizing radiation. This book explains the radiation processing of polymeric materials used in many industrial products including cars, airplanes, computers, and TVs. It even addresses emerging "green" issues like biomaterials and hydrogels.
This is the second, completely updated edition of a comprehensive book in which many of the world’s leading lung cancer specialists discuss the recent advances in the radiation oncology of lung cancer and reflect on the latest research findings. The first three sections cover the basic science of lung cancer, clinical investigations, including histology and staging, and a wide range of fundamental treatment considerations. Current treatment strategies for small cell and non-small cell lung cancer are then explained and evaluated in detail, with due attention to novel approaches that promise further improvements in outcome. The various types of treatment-related toxicity are discussed, and quality of life studies and prognostic factors are also considered. After evaluating the latest technological and biological advances, including IMRT, IMAT, cyber knife treatment, and tomotherapy, the book concludes by thorough consideration of specific aspects of clinical research in lung cancer.
Deals with radiation processing as a whole using a chemical perspective. Offers basic information on the procedures taking place and covers radiation dosimetry plus a wide range of actual and potential applications. Provides excellent coverage of radiation processing literature with bibliographies pertaining to key areas of radiation chemistry.
This book is a comprehensive guide to breast toxicity. Adjuvant radiation remains standard for a majority of women who undergo breast-conserving surgery for breast cancer, and indications for post-mastectomy and regional lymph node irradiation have also broadened with recent publications. At the same time, locoregional recurrence has declined and survival has improved in recent decades. In the current era of excellent breast cancer outcomes, then, considering the balance between toxicity and outcomes becomes paramount. Several recent editorials recommend considering toxicity against the potential benefit of adjuvant radiation in tailoring radiation decisions for individual patients. Thus, a clear understanding of the potential toxicities of adjuvant radiation for breast cancer is critical to optimizing outcomes in modern breast cancer management. Here, authors have collected recent data focused on toxicity of treatment that provide an opportunity for improving this optimization. Chapters cover both acute and late toxicity of radiation for breast cancer, including tailored risk assessment for each of these potential toxicities, considerations for including risk of toxicity in management decisions, and toxicity management strategies. This is an ideal guide for radiation oncologists, residents, and oncologists seeking to optimize care for their patients.
Images from CT, MRI, PET, and other medical instrumentation have become central to the radiotherapy process in the past two decades, thus requiring medical physicists, clinicians, dosimetrists, radiation therapists, and trainees to integrate and segment these images efficiently and accurately in a clinical environment. Image Processing in Radiation