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Up-to-Date Details on Using Ultrasound Imaging to Help Diagnose Various DiseasesDue to improvements in image quality and the reduced cost of advanced features, ultrasound imaging is playing a greater role in the diagnosis and image-guided intervention of a wide range of diseases. Ultrasound Imaging and Therapy highlights the latest advances in usin
The first resource of its kind, this book covers cutting-edge research on the use of nanoparticles for in vivo diagnostic medical imaging and therapy. It discusses a variety of nanoparticles, including quantum dots, carbon nanotubes, dendrimers, gold nanoshells, metal nanorods, micelles, liposomes, polymers, MRI iron oxide particles, and microbubbl
Comparative Diagnostic Pharmacology: Clinical and Research Applications in Living-System Models is the first evidence-based reference text devoted exclusively to the subject of applying pharmaceutical and biopharmaceutical agents as diagnostic probes in clinical medicine and investigative research.This unique and groundbreaking book is a versatile guide for clinicians and researchers interested in using pharmacologic agents to: Diagnose disease Assess physiological processes Identify the appropriateness of a therapeutic agent Determine appropriate dosing for therapeutic use. Extensively referenced and organized by major body systems, individual topics are listed in an evidence-based format according to specific disease processes or physiological processes of interest. Each entry also includes information on the mechanism of action, administration, and diagnostic interpretation. Descriptions have been provided for the application of diagnostic pharmaceuticals to assess a wide spectrum of diseases and physiological processes relevant to the fields of veterinary and human medicine. Comparative Diagnostic Pharmacology is useful not merely for pharmaceutical-oriented research investigations, but it will also prove invaluable for the monitoring and evaluation of physiological responses and disease processes in animal models.
The manipulation of cells and microparticles within microfluidic systems using external forces is valuable for many microscale analytical and bioanalytical applications. Acoustofluidics is the ultrasound-based external forcing of microparticles with microfluidic systems. It has gained much interest because it allows for the simple label-free separation of microparticles based on their mechanical properties without affecting the microparticles themselves. Microscale Acoustofluidics provides an introduction to the field providing the background to the fundamental physics including chapters on governing equations in microfluidics and perturbation theory and ultrasound resonances, acoustic radiation force on small particles, continuum mechanics for ultrasonic particle manipulation, and piezoelectricity and application to the excitation of acoustic fields for ultrasonic particle manipulation. The book also provides information on the design and characterization of ultrasonic particle manipulation devices as well as applications in acoustic trapping and immunoassays. Written by leading experts in the field, the book will appeal to postgraduate students and researchers interested in microfluidics and lab-on-a-chip applications.
The book provides a single volume covering detailed descriptions about various delivery systems, their principles and how these are put in use for the treatment of multiple diseases. It is divided into four sections where the first section deals with the introduction and importance of novel drug delivery system. The second section deals with the most advanced drug delivery systems like microbubbles, dendrimers, lipid-based nanoparticles, nanofibers, microemulsions etc., describing the major principles and techniques of the preparations of the drug delivery systems. The third section elaborates on the treatments of diverse diseases like cancer, topical diseases, tuberculosis etc. The fourth and final section provides a brief informative description about the regulatory aspects of novel drug delivery system that is followed in various countries.
This book will familiarize the reader with recent advances in echo imaging technology with special emphasis on echo enhancing agents. Several important strides have been made in this field during the past few years, especially in the contrast enhancement of conventional and color Doppler images. The book begins with chapters on the history of contrast echocardiography, the principles of contrast echo and descriptions of new contrast agents capable of transpulmonary passage following intravenous injection. Safety issues in contrast echocardiography are also discussed. The second section of the book deals with clinical uses of echo contrast agents. Their usefulness in the identification of cardiac structures and assessment of pathological lesions using both transthoracic and transesophageal echocardiography are fully discussed. Technical and practical considerations in the use of various contrast agents are also described. The use of contrast echo in the identification of cardiac sources of embolism as well as possible mechanisms and clinical significance of spontaneous contrast echoes are also covered. Six chapters fully discuss the basics of contrast enhancement of conventional and color Doppler images and its clinical utility in the noninvasive assessment of pulmonary artery pressure, regurgitant and stenotic lesions and in the delineation of coronary arteries. Another chapter describes the non-cardiac applications of the echo contrast enhancement technique. The final section of the book investigates the role of echo contrast enhancement in quantitative cardiovascular analysis.
Microbubbles and nanobubbles have several characteristics that are comparable with millimeter- and centimeter-sized bubbles. These characteristics are their small size, which results in large surface area and high bioactivity, low rising velocity, decreased friction drag, high internal pressure, large gas dissolution capacity, negatively charged surface, and ability to be crushed and form free radicals. Microbubbles and nanobubbles have found applications in a variety of fields such as engineering, agriculture, environment, food, and medicine. Microbubbles have been successfully used in aquacultures of oysters in Hiroshima, scallops in Hokkaido, and pearls in Mie Prefecture, Japan. This field has shown a strong potential for growth. This book comprehensively discusses microbubbles and nanobubbles and their application in aquaculture, environment, engineering, medicine, stock raising, agriculture, and marine industry. It presents their potential as a new technology that can be utilized globally.