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Healthcare decision makers in search of reliable information that compares health interventions increasingly turn to systematic reviews for the best summary of the evidence. Systematic reviews identify, select, assess, and synthesize the findings of similar but separate studies, and can help clarify what is known and not known about the potential benefits and harms of drugs, devices, and other healthcare services. Systematic reviews can be helpful for clinicians who want to integrate research findings into their daily practices, for patients to make well-informed choices about their own care, for professional medical societies and other organizations that develop clinical practice guidelines. Too often systematic reviews are of uncertain or poor quality. There are no universally accepted standards for developing systematic reviews leading to variability in how conflicts of interest and biases are handled, how evidence is appraised, and the overall scientific rigor of the process. In Finding What Works in Health Care the Institute of Medicine (IOM) recommends 21 standards for developing high-quality systematic reviews of comparative effectiveness research. The standards address the entire systematic review process from the initial steps of formulating the topic and building the review team to producing a detailed final report that synthesizes what the evidence shows and where knowledge gaps remain. Finding What Works in Health Care also proposes a framework for improving the quality of the science underpinning systematic reviews. This book will serve as a vital resource for both sponsors and producers of systematic reviews of comparative effectiveness research.
The Bulletin of the Atomic Scientists is the premier public resource on scientific and technological developments that impact global security. Founded by Manhattan Project Scientists, the Bulletin's iconic "Doomsday Clock" stimulates solutions for a safer world.
In Atlas of Nuclear Cardiology, Doctors Dilsizian and Narula have worked together with over a dozen leading authorities to capture the most up-to-date and pertinent information in the field of nuclear cardiology. This atlas is a modern and complete visual library of up-to-date information on the most current cardiovascular nuclear procedures in the clinical practice of cardiology. Together with detailed legends and extensive reference listings, the over 600 illustrations deliver comprehensive information. Diagnostic algorithms and schematic diagrams integrated with nuclear cardiology procedures are generously interspersed with color images to emphasize key concepts in cardiovascular physiology and metabolism. This vital reference provides a detailed and accurate insight into the noninvasive evaluation and quantification of myocardial perfusion, function, and metabolism.
The 19 chapters which comprise this text cover all aspects of heart failure, and are extremely readable and well-organized. The references selected for each chapter are highly sufficient and there is excellent coverage of all the pharmaceutical treatments, which have proven effective in the management of heart failure; moreover, there are chapters on the non-pharmacological management as well. The book instructs the physician in how to use the newer drugs, either singly or in combination and the clinical trials chapter gives the reader a balanced view of what is happening in research.
"A comprehensive, multifaceted book of astounding scope."--Bulletin of the History of Medicine