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Recent years have seen a greater industrial emphasis in undergraduate and postgraduate courses in the pharmaceutical and chemical sciences. However, textbooks have been slow to adapt, leaving the field without a text/reference that is both instructional and practical in the industrial setting – until now. A Handbook of Bioanalysis and Drug Metabolismis a stimulating new text that examines the techniques, methodology, and theory of bioanalysis, pharmacokinetics, and metabolism from the perspective of scientists with extensive professional experience in drug discovery and development. These three areas of research help drug developers to optimize the active component within potential drugs thereby increasing their effectiveness, and to provide safety and efficacy information required by regulators when granting a drug license. Professionals with extensive experience in drug discovery and development as well as specialized knowledge of the individual topics contributed to each chapter to create a current and well-credentialed text. It covers topics such as high performance liquid chromatography, protein binding, pharmacokinetics and drug–drug interactions. The unique industrial perspective helps to reinforce theory and develop valuable analytical and interpreting skills. This text is an invaluable guide to students in courses such as pharmaceutical science, pharmacology, chemistry, physiology and toxicology, as well as professionals in the biotechnology industry.
'Fundamental Toxicology' offers a comprehensive introduction to the subject specifically for chemists. The book has been approved by the International Union of Pure and Applied Chemists.
This popular and practical book is a comprehensive guide to diagnosing joint conditions and the benefits, and potential pitfalls, of steroid injections, an important tool in managing these problems used by an increasing range of practitioners. It considers all the practical aspects of injection as well as providing general information, discussing medico-legal issues and highlighting clinical errors to avoid. This sixth edition has been completely revised and expanded. Key features include: two new chapters on the evidence base and inflammatory arthropathy updated physiotherapy assessment and treatment options now incorporated within the chapters on joint injections full-colour photographs and additional explanatory illustrations The book describes, step-by-step, the required skills for each procedure, providing every practitioner with the knowledge needed to inject with confidence.
The Side Effects of Drugs Annual was first published in 1977. It has been continually published since then as a yearly update to the voluminous encyclopedia, Meyler's Side Effects of Drugs. Each new Annual continues to provide clinicians and medical investigators with a reliable and critical yearly survey of new data and trends in the area of adverse drug reactions and interactions. An international team of specialists has contributed to the informative Annual by critically interpreting it and by pointing to whatever is misleading. - Provides a critical yearly survey of new data and trends - Special reviews in this Annual include, among other topics, epidemiology of the use of ecstasy, paracetamol and the risk of asthma, combination vaccines/multiple immunizations, interactions of herbal medicines with warfarin, and tyrosine kinase inhibitors
Adverse events in patients caused by medical management are a serious and grossly underreported public health problem. One patient in ten entering hospital will suffer an adverse event of impairment, disability or death. This book is a major comprehensive examination of the incidence and causes of adverse events. Using data obtained from hospitals within the United Kingdom, United States and other developed countries, it examines the risk factors leading to errors, the human and financial costs, and the scope to reduce errors. In particular, it focuses on the need for a critical reappraisal of undergraduate teaching and clinical tuition. All healthcare professionals throughout primary and secondary care, including clinicians, managers and policy makers, and patient and carer groups, can benefit from reading this book. It identifies possible solutions and how adverse events and medication errors can be reduced, resulting in improved patient care.
Clinical skills procedures are a fundamental aspect of nursing care. The Royal Marsden Hospital Manual of Clinical Nursing Procedures Student Edition has been specially compiled for pre-registration students to include the essential procedures they need to know. The manual provides the underlying theory and evidence for procedures related to every aspect of a person's care. Procedures are based on the latest research findings and expert clinical advice, to enable student nurses to deliver clinically effective patient-focused care. Compact and portable –can be taken anywhere Includes the key evidence-based procedures students need to know Includes multiple-choice questions to help students test their knowledge Clear, user friendly and easy to understand All procedures include the rationale for each action and rate the validity of the supporting evidence Visit royalmarsdenmanual.com to‘Ask the editor’ Accompanying Lecturer companion site with Multiple choice questions & Powerpoint slides of all illustrations Accompanying Student companion site with Multiple choice questions
Nationally recognised as the definitive guide to clinical nursing skills, The Royal Marsden Manual of Clinical Nursing Procedures has provided essential nursing knowledge and up-to-date information on nursing skills and procedures for over 30 years. Now in its 9th edition, this full-colour manual provides the underlying theory and evidence for procedures enabling nurses to gain the confidence they need to become fully informed, skilled practitioners. Written with the qualified nurse in mind, this manual provides up–to–date, detailed, evidence–based guidelines for over 200 procedures related to every aspect of a person′s care including key information on equipment, the procedure and post-procedure guidance, along with full colour illustrations and photos. Following extensive market research, this ninth edition: contains the procedures and changes in practice that reflect modern acute nursing care includes thoroughly reviewed and updated evidence underpinning all procedures is organised and structured to represent the needs of a patient along their care pathway integrates risk-management into relevant chapters to ensure it is central to care contains revised procedures following ‘hands-on’ testing by staff and students at Kingston University is also available as an online edition
Kucers’ The Use of Antibiotics is the definitive, internationally-authored reference, providing everything that the infectious diseases specialist and prescriber needs to know about antimicrobials in this vast and rapidly developing field. The much-expanded Seventh Edition comprises 4800 pages in 3 volumes in order to cover all new and existing therapies, and emerging drugs not yet fully licensed. Concentrating on the treatment of infectious diseases, the content is divided into four sections - antibiotics, anti-fungal drugs, anti-parasitic drugs, and anti-viral drugs - and is highly structured for ease of reference. Each chapter is organized in a consistent format, covering susceptibility, formulations and dosing (adult and pediatric), pharmacokinetics and pharmacodynamics, toxicity, and drug distribution, with detailed discussion regarding clinical uses - a feature unique to this title. Compiled by an expanded team of internationally renowned and respected editors, with expert contributors representing Europe, Africa, Asia, Australia, South America, the US, and Canada, the Seventh Edition adopts a truly global approach. It remains invaluable for anyone using antimicrobial agents in their clinical practice and provides, in a systematic and concise manner, all the information required when prescribing an antimicrobial to treat infection.
Near death experiences fascinate everyone, from theologians to sociologists and neuroscientists. This groundbreaking book introduces the phenomenon of NDEs, their personal impact and the dominant scientific explanations. Taking a strikingly original cross-cultural approach and incorporating new medical research, it combines new theories of mind and body with contemporary research into how the brain functions. Ornella Corazza analyses dualist models of mind and body, discussing the main features of NDEs as reported by many people who have experienced them. She studies the use of ketamine to reveal how characteristics of NDEs can be chemically induced without being close to death. This evidence challenges the conventional ‘survivalist hypothesis’, according to which the near death experience is a proof of the existence of an afterlife. This remarkable book concludes that we need to move towards a more integrated view of embodiment, in order to understand what human life is and also what it can be. Ornella Corazza is a NDE researcher at the School of Oriental and African Studies (SOAS), University of London. In 2004-5 she was a Member of the 21st Century Centre of Excellence (COE) ‘Program on the Construction of Death and Life Studies’ at the University of Tokyo.