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What happens to "orphan" diseases that aren't big enough profit centers for the pharmaceutical industry or get caught in the web of government funding and academic research? Augie Nieto found out in the spring of 2005: At forty-seven years old he was diagnosed with ALS. Devastated, Augie struggled with depression and attempted suicide. When he awoke from a coma, with friends and family surrounding him, his sense of faith and mission were renewed. Fast-forward one year: Augie and his wife, Lynne, were profiled as "Real Heroes" on the Today show. Their determination to beat the disease had already led to major overhauls in the way ALS research was conducted. In partnership with the Muscular Dystrophy Association, Augie had set up a foundation and lab to coordinate and oversee ALS research and testing across the globe. By centralizing operations and championing an entrepreneurial approach to medical research, Augie and his team accomplished remarkable results in less than two years. Part inspiration, part business innovation, Augie's Quest illustrates how one person can make a meaningful difference. Praise for Augie Nieto: George H. W. Bush, former U.S. president: "Your contributions to the fitness industry are well known, and your dedication an inspiration." Lance Armstrong, seven-time "Le Tour de France" champion: "I think it says a lot about Augie, the fact that everybody came together regardless of whether or not it's for competing gyms or competing companies that make equipment. They all say, this is one of our own; this is a guy who's committed his life to our industry and has been dealt a serious blow. We're going to be there for him, we're going to say, we're here for you and we're part of the Quest." Arnold Schwarzenegger, governor of California: "Your success has been incredible. But you are so much more than just a successful businessman. You are the greatest husband, a great father, and a terrific friend. So,
Supported by case studies and testimonials from entrepreneurs using these best practice systems, former US SBA of the Year Clay Clark shares the specific action steps for successful business systems, hilarious stories from situations that every entrepreneur faces, and entrepreneurship factoids that are guaranteed to blow your mind.
In celebration of Princeton University's 250th anniversary, the mathematics department held a conference entitled "Prospects in Mathematics". The purpose of the conference was to speculate on future directions of research in mathematics. This collection of articles provides a rich panorama of current mathematical activity in many research areas. From Gromov's lecture on quantitative differential topology to Witten's discussion of string theory, new ideas and techniques transfixed the audience of international mathematicians. The volume contains 11 articles by leading mathematicians, including historical presentations by J. Milnor and D. Spencer. It provides a guide to some of the most significant mathematical work of the past decade.
Abraham Lincoln practiced law for nearly twenty-five years, five times longer than he served as president. Nonetheless, this aspect of his life was known only in the broadest outlines until the Lincoln Legal Papers project set to work gathering the surviving documentation of more than 5,600 of his cases. One of the first scholars to work in this vast collection, Mark E. Steiner goes beyond the hasty sketches of previous biographers to paint a detailed portrait of Lincoln the lawyer. This portrait not only depicts Lincoln's work for the railroads and the infamous case in which he defended the claims of a slaveholder; it also illustrates his more typical cases involving debt and neighborly disputes. Steiner describes Lincoln's legal education, the economics of the law office, and the changes in legal practice that Lincoln himself experienced as the nation became an industrial, capitalist society. Most important, Steiner highlights Lincoln's guiding principles as a lawyer. In contrast to the popular caricature of the lawyer as a scoundrel, Lincoln followed his personal resolve to be "honest at all events," thus earning the nickname "Honest Abe." For him, honesty meant representing clients to the best of his ability, regardless of his own beliefs about the justice of their cause. Lincoln also embraced a professional ideal that cast the lawyer as a guardian of order. He was as willing to mediate a dispute outside the courtroom in the interest of maintaining peace as he was eager to win cases before a jury. Over the course of his legal career, however, Lincoln's dedication to the community and his clients' personal interests became outmoded. As a result of the rise of powerful, faceless corporate clients and the national debate over slavery, Lincoln the lawyer found himself in an increasingly impersonal, morally ambiguous world.