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Jenner's famed papers detailing his discovery of the small pox vaccination, which has led to the eradication of the disease from the planet.
The story of the rise and fall of smallpox, one of the most savage killers in the history of mankind, and the only disease ever to be successfully exterminated (30 years ago next year) by a public health campaign.
The once-dreaded scourge of smallpox has been eradicated through barrier immunization. The eminent scientist Edward Jenner (1749-1823) was a pioneer in demonstrating that vaccination was an effective means of preventing smallpox. In the three groundbreaking treatises contained in this volume, originally published between 1798 and 1800, Jenner summarizes his evidence in favor of vaccination and describes individual cases.
In Japan, as late as the mid-nineteenth century, smallpox claimed the lives of an estimated twenty percent of all children born—most of them before the age of five. When the apathetic Tokugawa shogunate failed to respond, Japanese physicians, learned in Western medicine and medical technology, became the primary disseminators of Jennerian vaccination—a new medical technology to prevent smallpox. Tracing its origins from rural England, Jannetta investigates the transmission of Jennerian vaccination to and throughout pre-Meiji Japan. Relying on Dutch, Japanese, Russian, and English sources, the book treats Japanese physicians as leading agents of social and institutional change, showing how they used traditional strategies involving scholarship, marriage, and adoption to forge new local, national, and international networks in the first half of the nineteenth century. The Vaccinators details the appalling cost of Japan's almost 300-year isolation and examines in depth a nation on the cusp of political and social upheaval.
A history of the global spread of vaccination during the Napoleonic Wars, when millions of children were saved from smallpox.
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This book presents the state of art in the field of microbial zoonoses and sapronoses. It could be used as a textbook or manual in microbiology and medical zoology for students of human and veterinary medicine, including Ph.D. students, and for biomedicine scientists and medical practitioners and specialists as well. Surprisingly, severe zoonoses and sapronoses still appear that are either entirely new (e.g., SARS), newly recognized (Lyme borreliosis), resurging (West Nile fever in Europe), increasing in incidence (campylobacterosis), spatially expanding (West Nile fever in the Americas), with a changing range of hosts and/or vectors, with changing clinical manifestations or acquiring antibiotic resistance. The collective term for those diseases is (re)emerging infections, and most of them represent zoonoses and sapronoses (the rest are anthroponoses). The number of known zoonotic and sapronotic pathogens of humans is continually growing − over 800 today. In the introductory part, short characteristics are given of infectious and epidemic process, including the role of environmental factors, possibilities of their epidemiological surveillance, and control. Much emphasis is laid on ecological aspects of these diseases (haematophagous vectors and their life history; vertebrate hosts of zoonoses; habitats of the agents and their geographic distribution; natural focality of diseases). Particular zoonoses and sapronoses are then characterized in the following brief paragraphs: source of human infection; animal disease; transmission mode; human disease; epidemiology; diagnostics; therapy; geographic distribution.