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This is an enlarged, updated, color-illustrated new edition of the definitive clinical reference on in vitro fertilization and assisted reproduction. It contains 37 chapters by top-ranked specialists from around the world covering every aspect of investigation and therapeutic options as taught and practiced at the world-famous Bourn Hall Clinic. Large format, double-column pages. Includes bibliographic references, procedures, protocols and information sheets, and index.
Groundbreaking, comprehensive, and developed by a panel of leading international experts in the field, Textbook of Assisted Reproduction provides a multidisciplinary overview of the diagnosis and management of infertility, which affects 15% of all couples around the world. The book aims to cover all aspects of assisted reproduction. Particular attention is given to topics such as the assessment of infertile couples; assisted reproductive techniques (ARTs) including ovulation induction, intra uterine insemination (IUI), in vitro fertilization (IVF) and intracytoplasmic sperm injection (clinical and laboratory aspects); reproductive genetics; and obstetric and perinatal outcomes.
Now in its revised and expanded second edition - including over 20 new chapters - this comprehensive textbook remains a unique and accessible description of the current and developing diagnostic and treatment techniques and technologies comprising in vitro fertilization (IVF). Arranged thematically in sections, each chapter covers a key topic in IVF in a sensible presentation. Parts one and two describe the planning, design and organization of an ART unit and IVF laboratory and equipment and systems, respectively. The sections that follow provide detailed descriptions of IVF techniques, embryo culture methods, sperm processing and selection, insemination procedures, micromanipulation, embryo evaluation, cryopreservation, and embryo transfer. Concluding sections address issues of management and regulation of ART labs across the globe, as well as special topics and emerging techniques and devices. Chapter authors, all experts in the field, contribute their expertise from around the world. With the addition of learning key points and review questions at the beginning and end of each chapter, this new edition of In Vitro Fertilization is a readily accessible, high quality instructional resource for reproductive medicine trainees at all levels. Practicing reproductive endocrinologists, urologists, and embryologists also will find value in the book, as will infertility researchers.
Assisted reproduction techniques have led to the birth of 4 million babies worldwide Assisted reproduction techniques (ART), in particular in-vitro fertilization and intra-cytoplasmic sperm injection, are the most advanced forms of infertility treatment. They involve numerous counseling, medical, surgical and laboratory-based steps. At each step various problems and complications could be encountered that challenge even the most experienced ART practitioners. Moreover, patients with complex medical disorders may require ART, presenting further challenges. Assisted Reproduction Techniques will stimulate resourceful thinking in the ART practitioner when faced with these challenges. It outlines various management options, the reasoning behind them, and the evidence on which they are based to enable the practitioner to choose the most suitable solution for the needs of each patient. Written by 122 internationally renowned experts, Assisted Reproduction Techniques follows the patient's journey throughout the whole ART process, with chapters on: Counseling and preparation Ovarian stimulation Oocyte retrieval Embryo transfer The luteal phase The ART laboratory The male patient The ART pregnancy Each of the 100 concise chapters includes clinical cases, background, evidence-based practical management options, preventive measures and key-point summaries of the important details. Assisted Reproduction Techniques gives a wide-ranging practical guide to all those wishing to support couples who cannot conceive naturally.
Delivers current knowledge from global experts at the forefront of fertility and ART healthcare The first publication of its kind, this book on fertility and assisted reproductive technology (ART) is a globally focused, authoritative guide to state-of-the-art information about modern fertility and ART healthcare. Written for clinicians, public health officials, women’s health experts, scientists, students, scholars, and other interested individuals, the book encompasses theoretical, research, policy, and clinical practice aspects of fertility and ART healthcare. The book features the diverse contributions of multidisciplinary researchers, scholars, and clinicians from eight countries who explore contemporary health care perspectives regarding individuals and families dealing with infertility and fertility challenges including such advanced technologies as in-vitro fertilization, intrauterine insemination, and oocyte preservation. The book addresses theoretical underpinnings of fertility and ART healthcare including new ways of conceptualizing research and theoretical concepts. Practical aspects involved with administering and treating the many women and men whose lives are affected by fertility challenges are illuminated. Complex policy concerns resulting from the rapid advances in fertility and ART are considered. The health care needs of those seeking fertility evaluation and treatment including access to care locally and globally are examined in depth. The book also includes discussions about novel approaches and emerging populations in fertility and ART healthcare that expand the scope of care. Thought-provoking case examples from contemporary care practices will help the reader to synthesize information. Key Features: Delivers thought provoking ART research and practice issues for health care clinicians, scholars, and scientists Synthesizes evolving theory, research, clinical practice, and public policy concerns Addresses complex considerations within the practice and delivery of fertility and ART services Written by international thought leaders and emerging scholars on the forefront of ART technologies and other issues Includes case study exemplars to stimulate critical thinking and transform discussion about modern fertility and ART care
This fully updated new edition of a successful and popular practical guide is an indispensable account of modern in-vitro fertilization practice. Initial chapters cover theoretical aspects of gametogenesis and embryo development at the cellular and molecular level, while the latter half of the book describes the requisites for a successful IVF laboratory and the basic technologies in ART. Advanced techniques, including pre-implantation genetic diagnosis, vitrification and stem-cell technology, are comprehensively covered, providing up-to-date analyses of these groundbreaking technologies. This edition includes: • New practical techniques, including preservation of fertility for cancer patients, stem-cell biology/technology, vitrification and in-vitro maturation • A 'refresher' study review of fundamental principles of cell and molecular biology • The latest information available from animal and human research in reproductive biology Packed with a wealth of practical and scientific detail, this is a must for all IVF practitioners.
Personnel working in assisted reproductive technology often lack the opportunities for dedicated training in the specialized techniques and technologies required for the procedures. As such, success in the form of live birth rates can range from over 50% to less than 10% per treatment cycle. This comprehensive introductory textbook is an essential resource for trainee embryologists, medical students and nurses. The recent revolutions in biotechnology and molecular biology involved in delivering assisted reproductive services are thoroughly discussed. Basic knowledge such as the development and physiology of both male and female reproductive systems is covered, with practical aspects of IVF including gamete and embryo manipulation, cryopreservation and genetic testing explained in detail. A full description of the optimal structure and management of the IVF laboratory is given, helping ensure procedures are safe and effective. Extensive and highly detailed colour illustrations bring the content to life and aids readers in their understanding.
A comprehensive text on the process of human fertilization and reproduction and the technique of in-vitro fertilization and embryo transfer. Includes coverage of assisted fertilization and the potential applicability of genetic diagnosis of the pre-implantation embryo.
The scourge of infertility defeated doctors and scientists down the ages. But since the breakthrough with in vitro fertilization (IVF) and other assisted reproductive technologies (ARTs) after 1980, almost every patient who hopes to have children can be helped. This book is the amazing story of how IVF came to America. It is told by Howard W. Jones, Jr., M.D. who, with his late wife Georgeanna Jones, M.D., was the American pioneer of 'test-tube babies.' For them, it was a 'retirement job' after finishing careers at Johns Hopkins University where he was an internationally-acclaimed reproductive surgeon and Georgeanna was the first director of gynecological endocrinology. That they succeeded so well against the odds late in their careers and in the teeth of opposition from right-to-life groups depended on a number of chance opportunities and the building of a 'dream-team.' Following the lead of Patrick Steptoe and Robert Edwards (Nobel Prize, 2010) and the birth of Louise Brown in Great Britain, they achieved the first test-tube baby in the Americas - Elizabeth Carr, born in Norfolk in 1981. IVF clinics have subsequently sprouted across the globe, and now account for over 60,000 births annually in the USA, and more than five million babies have been born worldwide. The rapid social acceptance of IVF owes a great deal to these doctors, and Howard Jones, now well past his hundredth year, still inspires researchers to improve treatment options, and debates the ethics of ARTs. When IVF was still in its infancy, the Joneses were invited to join a panel at the Vatican City to advise Pope John Paul II about IVF. They were unable to persuade that pontiff, although Howard harbors a hope that Pope Francis will eventually open his arms to the new treatment. No one has been more influential than him in propelling IVF forward in the USA, and this memoir is Howard's account of how the controversial research he steered became one of the great medical victories of our time.
Offers a comprehensive guide to assisted reproductive technology surveillance, describing its history, global variations, and best practices.