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With over 100 illustrations, Volume 1 addresses the core disciplines of pharmaceutics (absorption, PK, excipients, tablet dosage forms, and packaging), and explores the challenges and paradigms of pharmaceutics.Key topics in Volume 1 include: principles of drug absorption, chemical kinetics, and drug stability pharmacokinetics the effect of rout
Handbook of Modern Pharmaceutical Analysis, Second Edition, synthesizes the complex research and recent changes in the field, while covering the techniques and technology required for today's laboratories. The work integrates strategy, case studies, methodologies, and implications of new regulatory structures, providing complete coverage of quality assurance from the point of discovery to the point of use. - Treats pharmaceutical analysis (PA) as an integral partner to the drug development process rather than as a service to it - Covers method development, validation, selection, testing, modeling, and simulation studies combined with advanced exploration of assays, impurity testing, biomolecules, and chiral separations - Features detailed coverage of QA, ethics, and regulatory guidance (quality by design, good manufacturing practice), as well as high-tech methodologies and technologies from "lab-on-a-chip" to LC-MS, LC-NMR, and LC-NMR-MS
In the previous few decades, the discipline of pharmaceutics has experienced substantial change. Today, more than ever, a thorough understanding of current pharmaceutics is required as the research pertaining to medication transport and formulation advances. For those studying, teaching, or working in the pharmaceutical sciences, this textbook, "Modern Pharmaceutics," is a vital tool. Gaining a comprehensive grasp of the concepts and applications of contemporary pharmaceutics is the aim of this course. This book offers a comprehensive yet fair review of the subject, covering everything from the fundamentals of drug delivery systems to the most recent developments in pharmaceutical technology. In order to help the reader navigate the complexity of pharmaceutics, the chapters in this book are carefully arranged. The book begins with the fundamental notions and moves on to more complex subjects, providing a thorough and progressive learning experience. Drug delivery methods, pharmaceutical formulations, cutting-edge technology, and ethical and regulatory issues are important areas of study. The emphasis in this work is on applying theoretical knowledge in real-world situations. The integration of case studies, real-world examples, and problem-solving activities serves to augment comprehension and cultivate critical thinking. We are also grateful to the instructors, reviewers, and writers who have helped us with this book by offering insightful comments and insightful ideas.
In the previous few decades, the discipline of pharmaceutics has experienced substantial change. Today, more than ever, a thorough understanding of current pharmaceutics is required as the research pertaining to medication transport and formulation advances. For those studying, teaching, or working in the pharmaceutical sciences, this textbook, "Modern Pharmaceutics," is a vital tool. Gaining a comprehensive grasp of the concepts and applications of contemporary pharmaceutics is the aim of this course. This book offers a comprehensive yet fair review of the subject, covering everything from the fundamentals of drug delivery systems to the most recent developments in pharmaceutical technology. The emphasis in this book is on applying theoretical knowledge in real-world situations. The integration of case studies, real-world examples, and problem-solving activities serves to augment comprehension and cultivate critical thinking. We are also grateful to the instructors, reviewers, and writers who have helped us with this book by offering insightful comments and insightful ideas. Their knowledge and commitment have been crucial in making sure this material satisfies the highest requirements for academic quality. With the aim of equipping, you with the information and abilities required to succeed in the dynamic and constantly changing area of pharmaceutics, we hope that "Modern Pharmaceutics" will be a crucial asset in your academic and professional quest.
The twentieth century has been a great success for modern medicine, and has resulted in the generation of a plethora of drugs to treat most common illnesses. However, in the light of increasing regulatory demands, spiralling costs and diminishing commercial returns, the question of how, when, where and whether to conduct pharmaceutical R&D has profound implications, and not just for those within the pharmaceutical industry. In response to these and other dilemmas, the authors define the processes involved in drug research, and examine the advantages and disadvantages of collaborative methods of drug research, and examine the roles that academia, CROs, small "biotechnology" companies and "research boutiques," and possibly even the "virtual research company" might play as contractors and collaborators.
This adaptation of Bentley's Textbook of Pharmaceutics follows the same goals as those of the previous edition, albeit in a new look. The content of the old edition has been updated and expanded and several new chapters, viz. Complexations, Stability Testing as per ICH Guidelines, Parenteral Formulations, New Drug Delivery Systems and Pilot Plant Manufacturing, have been included, with an intention to make the book more informative for the modern pharmacists. The book has six sections: - Section I deals with the physicochemical principles. Two new chapters: Complexations and ICH Guidelines for Stability Testing, have been added to make it more informative. - Section II conveys the information regarding pharmaceutical unit operations and processes. - Section III describes the area of pharmaceutical practice. Extensive recent updates have been included in many chapters of this section. Two new chapters: Parenteral Formulations and New Drug Delivery Systems, have been added. - Section IV contains radioactivity principles and applications. - Section V deals with microbiology and animal products. - Section VI contains the formulation and packaging aspects of pharmaceuticals. Pilot Plant Manufacturing concepts are added as a new chapter, which may be beneficial to readers to understand the art of designing of a plant from the pilot plant model.
In the dynamic field of pharmaceutical sciences, analytical techniques play an indispensable role. The precision and reliability of these methods are crucial for ensuring the quality, safety, and efficacy of pharmaceutical products throughout their development, manufacturing, and regulatory approval stages. Recent decades have seen significant advancements in analytical instrumentation, methodologies, and data analysis, leading to a transformative shift in pharmaceutical analytics. This book is intended as a comprehensive guide to modern pharmaceutical analytical techniques, aiming to bridge the gap between theoretical knowledge and practical application in the evolving pharmaceutical industry. It serves as a valuable resource for students, researchers, and professionals involved in pharmaceutical analysis, providing a systematic overview of the latest analytical tools and strategies used in drug discovery, development, and quality control. Each chapter is carefully designed to offer detailed insights into the theoretical foundations, practical considerations, and recent advancements relevant to each analytical technique. The content is enriched with illustrative examples, case studies, and critical discussions. Special attention is given to emerging trends, such as nanotechnology-enabled analytical platforms, microfluidic-based assays, and in silico predictive modeling, highlighting the transformative potential of these cutting-edge technologies in pharmaceutical analytics. We hope this book will foster interdisciplinary collaboration, drive innovation, and promote best practices in pharmaceutical analytical sciences. We express our sincere gratitude to the contributors for their scholarly efforts and to the readers for their interest and engagement in this work.
Pharmaceutical analysis determines the purity, concentration, active compounds, shelf life, rate of absorption in the body, identity, stability, rate of release etc. of a drug. Testing a pharmaceutical product involves a variety of chemical, physical and microbiological analyses. It is reckoned that over £10 billion is spent annually in the UK alone on pharmaceutical analysis, and the analytical processes described in this book are used in industries as diverse as food, beverages, cosmetics, detergents, metals, paints, water, agrochemicals, biotechnological products and pharmaceuticals. This is the key textbook in pharmaceutical analysis, now revised and updated for its fourth edition. Worked calculation examples Self-assessment Additional problems (self tests) Practical boxes Key points boxes New chapter on electrochemical biosensors. New chapter on the quality control of biotechnologically produced drugs. Extended chapter on molecular emission spectroscopy. Now comes with an e-book on StudentConsult. Self-assessment is interactive in the accompanying online e-book. 65 online animations show concepts such as ionization partitioning of drug molecules etc. ~
This textbook describes a variety of dosage forms and their clinical importance and use. The use and behaviour of dosage forms in different age groups and patient groups will also be considered along with recent developments such as personalised therapies and genomics. It contains relevant examples and clinical case studies.
Building on the strengths of previous editions, the Sixth Edition of Modern Pharmacology with Clinical Applications continues to provide an up-to-date and comprehensive textbook for students of pharmacology. Focusing on the clinical application of drugs within a context of the major principles of pharmacology, this text supplies both students and faculty with an introduction to modern pharmacotherapeutics.