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Nearly all our safety data collection and reporting systems are backwardlooking: incident reports; dashboards; compliance monitoring systems; and so on. This book shows how we can use safety data in a forward-looking, predictive sense. Predictive Safety Analytics: Reducing Risk through Modeling and Machine Learning contains real use cases where organizations have reduced incidents by employing predictive analytics to foresee and mitigate future risks. It discusses how Predictive Safety Analytics is an opportunity to break through the plateau problem where safety rate improvements have stagnated in many organizations. The book presents how the use of data, coupled with advanced analytical techniques, including machine learning, has become a proven and successful innovation. Emphasis is placed on how the book can “meet you where you are” by illuminating a path to get there, starting with simple data the organization likely already has. Highlights of the book are the real examples and case studies that will assist in generating thoughts and ideas for what might work for individual readers and how they can adapt the information to their particular situations. This book is written for professionals and researchers in system reliability, risk and safety assessment, quality control, operational managers in selected industries, data scientists, and ML engineers. Students taking courses in these areas will also find this book of interest to them.
Nearly all our safety data collection and reporting systems are backwardlooking: incident reports; dashboards; compliance monitoring systems; and so on. This book shows how we can use safety data in a forward-looking, predictive sense. Predictive Safety Analytics: Reducing Risk through Modeling and Machine Learning contains real use cases where organizations have reduced incidents by employing predictive analytics to foresee and mitigate future risks. It discusses how Predictive Safety Analytics is an opportunity to break through the plateau problem where safety rate improvements have stagnated in many organizations. The book presents how the use of data, coupled with advanced analytical techniques, including machine learning, has become a proven and successful innovation. Emphasis is placed on how the book can “meet you where you are” by illuminating a path to get there, starting with simple data the organization likely already has. Highlights of the book are the real examples and case studies that will assist in generating thoughts and ideas for what might work for individual readers and how they can adapt the information to their particular situations. This book is written for professionals and researchers in system reliability, risk and safety assessment, quality control, operational managers in selected industries, data scientists, and ML engineers. Students taking courses in these areas will also find this book of interest to them.
Applied Predictive Modeling covers the overall predictive modeling process, beginning with the crucial steps of data preprocessing, data splitting and foundations of model tuning. The text then provides intuitive explanations of numerous common and modern regression and classification techniques, always with an emphasis on illustrating and solving real data problems. The text illustrates all parts of the modeling process through many hands-on, real-life examples, and every chapter contains extensive R code for each step of the process. This multi-purpose text can be used as an introduction to predictive models and the overall modeling process, a practitioner’s reference handbook, or as a text for advanced undergraduate or graduate level predictive modeling courses. To that end, each chapter contains problem sets to help solidify the covered concepts and uses data available in the book’s R package. This text is intended for a broad audience as both an introduction to predictive models as well as a guide to applying them. Non-mathematical readers will appreciate the intuitive explanations of the techniques while an emphasis on problem-solving with real data across a wide variety of applications will aid practitioners who wish to extend their expertise. Readers should have knowledge of basic statistical ideas, such as correlation and linear regression analysis. While the text is biased against complex equations, a mathematical background is needed for advanced topics.
The goal of this research was to integrate a previously validated and reliable safety model, called Continuous Hazard Tracking and Failure Prediction Methodology (CHTFPM), into a software application. This led to the development of a safety management information system (PSMIS). This means that the theory or principles of the CHTFPM were incorporated in a software package; hence, the PSMIS is referred to as CHTFPM management information system (CHTFPM MIS). The purpose of the PSMIS is to reduce the time and manpower required to perform predictive studies as well as to facilitate the handling of enormous quantities of information in this type of studies. The CHTFPM theory encompasses the philosophy of looking at the concept of safety engineering from a new perspective: from a proactive, than a reactive, viewpoint. That is, corrective measures are taken before a problem instead of after it happened. That is why the CHTFPM is a predictive safety because it foresees or anticipates accidents, system failures and unacceptable risks; therefore, corrective action can be taken in order to prevent all these unwanted issues. Consequently, safety and reliability of systems or processes can be further improved by taking proactive and timely corrective actions. Quintana, Rolando Kennedy Space Center NAG10-331
A. N. WORDEN, D. V. PARKE AND J. MARKS THE BACKGROUND There is nothing new about the fact that chemical substances derived either from natural products or by synthetic means .. can give rise to toxicity in animals and human beings, and that they must be subjected to controls. The earliest writings speak of such toxicity and, from the times of ancient Egypt and in the Old Tes tament, controls have existed[l]. In the Middle Ages Paracelsus (1493-1541) noted that "All things are poisons, for there is nothing without poisonous qualities. It is only the dose which makes a thing a poison", and hence he stressed the importance of dose relative to toxic reactions [ 2] . Most of the early controls concentrated on substances that were to be deliberately administered to the human subject in the form of medicines. Legislation for many centuries was mainly con cerned with regulating the activities of apothecaries and physicians. The Royal College of Physicians, for example, was originally established to control the activities of physicians within London. Among the controls which it exerted was that over the use of medicinal substances. Such controls were, however, poor, based as they were on hearsay evidence of toxicity. For many centuries no means existed for the accurate determination of toxicity.
The process of developing predictive models includes many stages. Most resources focus on the modeling algorithms but neglect other critical aspects of the modeling process. This book describes techniques for finding the best representations of predictors for modeling and for nding the best subset of predictors for improving model performance. A variety of example data sets are used to illustrate the techniques along with R programs for reproducing the results.
Personalized Predictive Modeling in Diabetes features state-of-the-art methodologies and algorithmic approaches which have been applied to predictive modeling of glucose concentration, ranging from simple autoregressive models of the CGM time series to multivariate nonlinear regression techniques of machine learning. Developments in the field have been analyzed with respect to: (i) feature set (univariate or multivariate), (ii) regression technique (linear or non-linear), (iii) learning mechanism (batch or sequential), (iv) development and testing procedure and (v) scaling properties. In addition, simulation models of meal-derived glucose absorption and insulin dynamics and kinetics are covered, as an integral part of glucose predictive models. This book will help engineers and clinicians to: select a regression technique which can capture both linear and non-linear dynamics in glucose metabolism in diabetes, and which exhibits good generalization performance under stationary and non-stationary conditions; ensure the scalability of the optimization algorithm (learning mechanism) with respect to the size of the dataset, provided that multiple days of patient monitoring are needed to obtain a reliable predictive model; select a features set which efficiently represents both spatial and temporal dependencies between the input variables and the glucose concentration; select simulation models of subcutaneous insulin absorption and meal absorption; identify an appropriate validation procedure, and identify realistic performance measures. Describes fundamentals of modeling techniques as applied to glucose control Covers model selection process and model validation Offers computer code on a companion website to show implementation of models and algorithms Features the latest developments in the field of diabetes predictive modeling