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A new information and communication technology (ICT) has been deployed in the battle against Parkinson’s disease, a neurodegenerative disorder that is both progressive and disabling with significant impact on quality of life. This book explains the experience following from the achieved results in the REMPARK project on Parkinson’s disease management up to the launch of a new medical product to the European market, STAT-ONTM. The new medical device, STAT-ONTM is a real Holter for the motor symptoms associated to PD. It provides objective information about the severity and distribution of PD motor symptoms and their fluctuations in daily life, allowing for an unbiased and correct monitoring of the patient. This real-time remote monitoring solution gives additional information to neurologists, opening up new possibilities for more effective treatment, more accurate control in clinical trials, and for early detection of motor complications. The number of PD patients is continuously rising, adding complexity, especially in the management at the level of public health. It is an incurable disease, with a symptomatic treatment that tries to alleviate the associated symptoms through a correct adjustment of the medication. For this reason, it is also very important to be aware of changes in the manifestation of the symptoms, which may indicate the need for an adjustment or even a change in the therapy strategy. The intensive complementary use of STAT-ONTM by neurologists, health professionals and researchers, will increase the independence and quality of life of patients, improving their disease management, and contributing to a deeper understanding of the nature of the disease.
Advances in Clinical Chemistry, Volume 123, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians, and research scientists. - Provides the most up-to-date technologies in clinical chemistry and clinical laboratory science - Authored by world renowned clinical laboratory scientists, physicians, and research scientists - Presents the international benchmark for novel analytical approaches in the clinical laboratory
This collection of pediatric clinical cases focus on multiple sclerosis, neuromyelitis optica, acute disseminated encephalomyelitis and mimics. Dedicated sections on diseases affecting the brain, brainstem, spinal cord and the optic nerve feature chapters that include the diagnostic work up, therapeutic management and case outcome. Typical and atypical presentations of various pediatric demyelinating diseases also emphasize therapy response and those that breakthrough on treatment. Filling a critical gap in the literature on inflammatory disorders of the central nervous system, all those that treat patients with these rare and challenging disorders will find this book extremely helpful for their daily clinical practice.
Congenital Heart Disease in Pediatric and Adult Patients: Anesthetic and Perioperative Management provides a comprehensive, up-to-date overview of care of the pediatric patient undergoing cardiac surgery and anesthesia. After introductory chapters that encompass pediatric cardiovascular embryology, physiology and pharmacology, diagnostic approaches and preoperative considerations are explained. The intraoperative management of a wide range of specific lesions is then discussed, with full descriptions of anesthesia plans added with descriptions on diagnostic methods and surgical interventions. Postoperative care is also addressed, and a concluding section considers anesthesia outside the cardiac operating room. In the twenty-first century, advances in minimally invasive technology have led to the introduction of a wide array of pediatric cardiac procedures. More traditional surgical procedures have also been transformed by new devices and surgical approaches. The cardiac anesthesiologist is faced with an ever-increasing role in the perioperative care of pediatric patients undergoing cardiologic procedures in operating rooms, as well as less conventional locations. In this book, accomplished experts from around the world in the fields of pediatric anesthesia, cardiology, and cardiac surgery describe the multiple facets of caring for this very unique patient population.
A new information and communication technology (ICT) has been deployed in the battle against Parkinson's disease, a neurodegenerative disorder that is both progressive and disabling with significant impact on quality of life. This book explains the experience following from the achieved results in the REMPARK project on Parkinson's disease management up to the launch of a new medical product to the European market, STAT-ON(tm). The new medical device, STAT-ON(tm) is a real Holter for the motor symptoms associated to PD. It provides objective information about the severity and distribution of PD motor symptoms and their fluctuations in daily life, allowing for an unbiased and correct monitoring of the patient. This real-time remote monitoring solution gives additional information to neurologists, opening up new possibilities for more effective treatment, more accurate control in clinical trials, and for early detection of motor complications. The number of PD patients is continuously rising, adding complexity, especially in the management at the level of public health. It is an incurable disease, with a symptomatic treatment that tries to alleviate the associated symptoms through a correct adjustment of the medication. For this reason, it is also very important to be aware of changes in the manifestation of the symptoms, which may indicate the need for an adjustment or even a change in the therapy strategy. The intensive complementary use of STAT-ON(tm) by neurologists, health professionals and researchers, will increase the independence and quality of life of patients, improving their disease management, and contributing to a deeper understanding of the nature of the disease. The Open Access version of this book, available at http://www.taylorfrancis.com, has been made available under a Creative Commons [Attribution-Non-Commercial (CC-BY-NC)] 4.0 license.
Pocket Emergency Medicine, Fourth Edition, provides accurate, actionable, and easily accessible information for clinicians on the front lines of emergency care. Designed to be used at the bedside, it’s an outstanding go-to source for the essential information you need to care for patients in life-threatening situations. This volume in the popular Pocket Notebook series provides a concise and focused review of the entire field of emergency medicine — from history and physical exam to differential diagnosis testing to therapeutics to disposition – all in one easy-to-navigate looseleaf notebook.
This book provides in-depth insights into use cases implementing artificial intelligence (AI) applications at the edge. It covers new ideas, concepts, research, and innovation to enable the development and deployment of AI, the industrial internet of things (IIoT), edge computing, and digital twin technologies in industrial environments. The work is based on the research results and activities of the AI4DI project, including an overview of industrial use cases, research, technological innovation, validation, and deployment. This book’s sections build on the research, development, and innovative ideas elaborated for applications in five industries: automotive, semiconductor, industrial machinery, food and beverage, and transportation. The articles included under each of these five industrial sectors discuss AI-based methods, techniques, models, algorithms, and supporting technologies, such as IIoT, edge computing, digital twins, collaborative robots, silicon-born AI circuit concepts, neuromorphic architectures, and augmented intelligence, that are anticipating the development of Industry 5.0. Automotive applications cover use cases addressing AI-based solutions for inbound logistics and assembly process optimisation, autonomous reconfigurable battery systems, virtual AI training platforms for robot learning, autonomous mobile robotic agents, and predictive maintenance for machines on the level of a digital twin. AI-based technologies and applications in the semiconductor manufacturing industry address use cases related to AI-based failure modes and effects analysis assistants, neural networks for predicting critical 3D dimensions in MEMS inertial sensors, machine vision systems developed in the wafer inspection production line, semiconductor wafer fault classifications, automatic inspection of scanning electron microscope cross-section images for technology verification, anomaly detection on wire bond process trace data, and optical inspection. The use cases presented for machinery and industrial equipment industry applications cover topics related to wood machinery, with the perception of the surrounding environment and intelligent robot applications. AI, IIoT, and robotics solutions are highlighted for the food and beverage industry, presenting use cases addressing novel AI-based environmental monitoring; autonomous environment-aware, quality control systems for Champagne production; and production process optimisation and predictive maintenance for soybeans manufacturing. For the transportation sector, the use cases presented cover the mobility-as-a-service development of AI-based fleet management for supporting multimodal transport. This book highlights the significant technological challenges that AI application developments in industrial sectors are facing, presenting several research challenges and open issues that should guide future development for evolution towards an environment-friendly Industry 5.0. The challenges presented for AI-based applications in industrial environments include issues related to complexity, multidisciplinary and heterogeneity, convergence of AI with other technologies, energy consumption and efficiency, knowledge acquisition, reasoning with limited data, fusion of heterogeneous data, availability of reliable data sets, verification, validation, and testing for decision-making processes.
For years lipids have fascinated cell biologists and biochemists due to their profound effects on cell function. "Cellular Lipid Metabolism" highlights new concepts and recent findings, but also reviews important discoveries made in the past. Outstanding international experts contribute 13 chapters on the genetics, molecular and cell biology of lipids. Presenting analyses at the molecular level they reveal the principles by which cellular lipid metabolism functions. Further, numerous intriguing observations that cannot yet be explained are identified, stimulating the readers to future studies. This book provides an invaluable source of information for biomedical researchers in energy metabolism, vascular biology, endocrinology and lipidology.
Written by Jerome Sarris and Jon Wardle, Clinical Naturopathy: An evidence-based guide to practice articulates evidence-based clinical practice. It details the principles, treatment protocols and interventions at the forefront of naturopathic practice in the 21st century. Clinical Naturopathy equips you to critically evaluate your patients, analyse treatment protocols, and provide evidence-based prescriptions. - A rigorously researched update of common clinical conditions and their naturopathic treatment according to evidence-based guidelines - Treatment decision trees - Outline of core principles of naturopathic practice - Herb–drug interactions table - Laboratory reference values - Food sources of nutrients - Cancer medication interactions - Includes an Enhanced eBook version with purchase. The enhanced eBook allows the end user to access all of the text, figures, and references from the book on a variety of devices.