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Musculoskeletal diseases are rapidly becoming a major health concern. The incidence of osteoarthritis, the most common arthritic disorder, is increasing steadily due to the graying of the world population. This disease is responsible of human life, a time in for significant morbidity, particularly in the second half which the quality of life is of primary importance. The aim of this publication is to bring to physicians and scientists a comprehensive overview of the field, from molecules to men. The direct costs related to osteoarthritis have been increasing steadily over the years and will soon be comparable to those of other major illnesses, such as cardiovascular diseases. This, of course, does not take into account all of the other costs related to the disease which often cannot be simply calculated in dollars and cents. There has been a great deal of renewed interest in osteoarthritis in the last few decades. This has been brought on by the need to improve our knowledge of all aspects of the disease, especially with regard to its etiopathogenesis and treatment. The most recent findings and developments on the structural, bio chemical, biomechanical and molecular changes observed in clinical and ex perimental osteoarthritis are presented in this book.
This book is published open access under a CC BY 4.0 license. White Paper on Joint Replacement This White Paper details the status of hip and knee arthroplasty care in Germany. Hip and knee replacements are amongst the most frequently performed procedures and usually become necessarily due to age-related wear of the joint, osteoarthritis and fractures of the femoral neck. In light of demographic change, demands with regard to standards of care and the procedures are likely to rise. Contents • This White Paper contains information on indications, procedures, health economic aspects and the healthcare system stakeholders involved. • It portrays current developments with regard to the prevalence of hip and knee arthroplasty, the healthcare situation and quality of care within the chain of medical care. • This book is complemented by a chapter assessing the current situation from an expert perspective with contributions from renowned experts in the fields of science, medical technology and medical practice. This book addresses people involved in shaping and representing the healthcare system from a variety of fields including medical professions, health insurances and health sciences as well as journalists and patient representatives.
This comprehensive reference on total knee arthroplasty describes all surgical techniques and prosthetic designs for primary and revision arthroplasty, discusses every aspect of patient selection, preoperative planning, and intraoperative and postoperative care.
This perennial bestseller is an ideal introductions to epidemiology in health care. The fifith editon retains the book's simplicity and brevity, at the same time providing the reader with the core elements of epidemiology needed in health care practice and research. The text has been revised throughout, with new examples introduced to bring the book right up to date.
An authoritative investigation of the sources andtreatment of osteoarthritic joint pain Millions of people throughout the world suffer from osteoarthritis (OA)—a medical condition causing its sufferers excruciating pain that is often disabling. This is the first book to offer clinicians an in-depth understanding of the biological sources of osteoarthritic pain and how they can be treated. Here, a team of leading international authorities has contributed state-of-the-art information on: The Neuroscience of Articular Pain—spinal and peripheral mechanisms of joint pain; experimental models for the study of osteoarthritic pain; inflammatory mediators and nociception in arthritis; phantoms in rheumatology; and more Osteoarthritis and Pain—joint mechanisms and neuromuscular aspects of OA; bone pain and pressure in OA joints; structural correlates of OA pain; and more Treatment of Osteoarthritic Pain—general approaches to treatment; treatments targeting pain receptors; treatments targeting biomechanical abnormalities; and treatments targeting inflammation Whether you're a medical professional, researcher, student, or a generalist or specialist focusing on pain or arthritis, this is your one-stop reference for understanding and treating joint pain in osteoarthritis.
Written by the foremost experts, this text is a comprehensive clinical reference on osteoarthritis. Chapters review current information on the epidemiology, etiopathogenesis, and pathology of osteoarthritis, the biochemistry and molecular and cell biology of articular cartilage, and experimental models of osteoarthritis. Major sections focus on clinical presentations, roentgenologic and laboratory diagnosis, and treatment, including pharmacologic treatment, intra-articular therapy, surgery, arthroscopy, and complementary and alternative medicine. The authors discuss the indications, outcomes, and complications of various orthopaedic procedures. Chapters present orthopaedic approaches to osteoarthritis of various joints—the shoulder, hand, wrist, elbow, hip, knee, foot, ankle, and cervical, thoracic, and lumbar spine.
This brand new textbook of rheumatoid arthritis (RA) is an important addition to the Oxford Textbooks in Rheumatology series, and provides a comprehensive overview of both the scientific and clinical aspects of the disease. Divided into eight sections - from the history, diagnosis, and epidemiology of the disease, through the pathogenesis, clinical presentation, and assessment to treatments and management strategies, both drug- and non-drug based - each chapter is written by leading clinicians and scientists in the field to deliver a contemporary view of RA. During the past two decades there have been revolutionary changes in the understanding and management of rheumatoid arthritis, in particular the development of biological treatments. This has had wide-ranging effects on almost all aspects of treatment, from effectiveness and intensity to the nature and the cost. Providing a comprehensive account of the modern ideas about the disease, the Oxford Textbook of Rheumatoid Arthritis is a key new addition to the literature, with each chapter providing a detailed background, key recent advances, and areas of doubt and future developments. Featuring over 170 photographs, radiological images, and clinical charts to aid both diagnosis and illustrate the rationale behind key scientific studies, this new title will prove an indispensable resource for specialist rheumatologists, trainees in rheumatology, and other members of the multi-disciplinary team.
WHY DO YOUR KNEES HURT? WHAT CAN YOU DO ABOUT IT? Going beyond quick fixes, a leading orthopedic surgeon shows you how to stop damaging and start saving your knees, the body's hardest-working and most complex joint. Once you understand the source of your pain, whether from sports or overuse injuries, osteoarthritis, tendinitis, heredity, or a host of other causes -- then you can choose the best up-to-the-minute treatments that are right for you. You'll learn everything you need to know about: •Getting the right diagnosis •Differences between men's and women's knees •Treating the athlete's knee •Simple exercises to reduce pain •Medication •Physical therapy •Complementary and alternative remedies •Arthroscopy and other surgical options •Knee replacement ...and much more. You'll also find everyday wisdom for protecting your knees from wear and tear, and practical advice on lifestyle changes that can turn back the clock on your knee pain.
This comprehensive text examines the physical and mental repercussions of pain among the elderly, finding theoretical bases in such fields as dynamic psychology, psychophysics, behavior modification, pharmacology, and nutrition. The book covers the basic topics of biobehaviorism, psychosocial and psychodynamic aspects, and clinical techniques as they pertain to treatment of elderly patients. The authors of the book's 17 chapters are all esteemed specialists on particular aspects of pain and aging, and all provide state-of-the-science solutions to quality-of-life problems associated with the elderly.