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The 6th Computer Applications in Biotechnology (CAB6) conference was a continuation of 2 series of events: the IFAC symposia on Modelling and Control of Biotechnical Processes and the International Conferences on Computer Applications in Fermentation Technology. This conference provided the opportunity for both sides, leading researchers and industrial practitioners, in this interdisciplinary field to exchange new ideas and technology; concepts and solutions. This postprint volume contains all those papers which were presented at the conference.
The ICANNGA series of Conferences has been organised since 1993 and has a long history of promoting the principles and understanding of computational intelligence paradigms within the scientific community and is a reference for established workers in this area. Starting in Innsbruck, in Austria (1993), then to Ales in Prance (1995), Norwich in England (1997), Portoroz in Slovenia (1999), Prague in the Czech Republic (2001) and finally Roanne, in France (2003), the ICANNGA series has established itself for experienced workers in the field. The series has also been of value to young researchers wishing both to extend their knowledge and experience and also to meet internationally renowned experts. The 2005 Conference, the seventh in the ICANNGA series, will take place at the University of Coimbra in Portugal, drawing on the experience of previous events, and following the same general model, combining technical sessions, including plenary lectures by renowned scientists, with tutorials.
The growth in the Bioinformatics and Computational Biology fields over the last few years has been remarkable and the trend is to increase its pace. In fact, the need for computational techniques that can efficiently handle the huge amounts of data produced by the new experimental techniques in Biology is still increasing driven by new advances in Next Generation Sequencing, several types of the so called omics data and image acquisition, just to name a few. The analysis of the datasets that produces and its integration call for new algorithms and approaches from fields such as Databases, Statistics, Data Mining, Machine Learning, Optimization, Computer Science and Artificial Intelligence. Within this scenario of increasing data availability, Systems Biology has also been emerging as an alternative to the reductionist view that dominated biological research in the last decades. Indeed, Biology is more and more a science of information requiring tools from the computational sciences. In the last few years, we have seen the surge of a new generation of interdisciplinary scientists that have a strong background in the biological and computational sciences. In this context, the interaction of researchers from different scientific fields is, more than ever, of foremost importance boosting the research efforts in the field and contributing to the education of a new generation of Bioinformatics scientists. PACBB‘12 hopes to contribute to this effort promoting this fruitful interaction. PACBB'12 technical program included 32 papers from a submission pool of 61 papers spanning many different sub-fields in Bioinformatics and Computational Biology. Therefore, the conference will certainly have promoted the interaction of scientists from diverse research groups and with a distinct background (computer scientists, mathematicians, biologists). The scientific content will certainly be challenging and will promote the improvement of the work that is being developed by each of the participants.
Computers that `program themselves' has long been an aim of computer scientists. Recently genetic programming (GP) has started to show its promise by automatically evolving programs. Indeed in a small number of problems GP has evolved programs whose performance is similar to or even slightly better than that of programs written by people. The main thrust of GP has been to automatically create functions. While these can be of great use they contain no memory and relatively little work has addressed automatic creation of program code including stored data. This issue is the main focus of Genetic Programming, and Data Structures: Genetic Programming + Data Structures = Automatic Programming!. This book is motivated by the observation from software engineering that data abstraction (e.g., via abstract data types) is essential in programs created by human programmers. This book shows that abstract data types can be similarly beneficial to the automatic production of programs using GP. Genetic Programming and Data Structures: Genetic Programming + Data Structures = Automatic Programming! shows how abstract data types (stacks, queues and lists) can be evolved using genetic programming, demonstrates how GP can evolve general programs which solve the nested brackets problem, recognises a Dyck context free language, and implements a simple four function calculator. In these cases, an appropriate data structure is beneficial compared to simple indexed memory. This book also includes a survey of GP, with a critical review of experiments with evolving memory, and reports investigations of real world electrical network maintenance scheduling problems that demonstrate that Genetic Algorithms can find low cost viable solutions to such problems. Genetic Programming and Data Structures: Genetic Programming + Data Structures = Automatic Programming! should be of direct interest to computer scientists doing research on genetic programming, genetic algorithms, data structures, and artificial intelligence. In addition, this book will be of interest to practitioners working in all of these areas and to those interested in automatic programming.
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